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Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

A new study suggests that coronaviruses such as SARS-CoV-2 depend on a furin cleavage site between the S1/S2 subunits to enhance viral infectivity.

20 Jan 2022

The effect of different heterologous vaccination intervention strategies on the winter 2020 COVID-19 wave in the US

Researchers demonstrated the effect of different heterologous vaccine interventions on COVID-19 caseloads, hospitalization, and mortality in the US.

20 Jan 2022

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Eikonoklastes Therapeutics, a preclinical stage biopharmaceutical company, today announced it has completed a license with the University of California San Diego to add a novel gene therapy for the treatment of neurodegenerative diseases.

20 Jan 2022

Variants of SARS-CoV-2 and preventive strategies

A recent review article published in the journal Advanced Science reviewed the features of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants. Using a physical and materials science perspective, the review also summarizes the most significant variants of SARS-CoV-2 encountered to date as well as possible preventive strategies.

19 Jan 2022

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Glioblastoma, an aggressive cancer in the brain or spinal cord, has proven stubbornly resistant to newer immunotherapies. And radiation and chemotherapy, the standard treatment for glioblastoma, result in fewer than 10% of patients surviving longer than five years after diagnosis.

19 Jan 2022

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers at the University of Illinois Chicago.

19 Jan 2022

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

19 Jan 2022

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

A recent review discusses the engineering versatility of polymeric nanoparticles - making a good therapeutic alternative against coronavirus diseases.

19 Jan 2022

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

New therapies for autoimmune rheumatic diseases (AIRDs) that are designed to better regulate lipid (fat) metabolism, could significantly reduce the harmful side-effects caused by conventional treatments, finds a new large-scale review led by UCL researchers.

19 Jan 2022

Antibody combination produces a synergistic response in difficult-to-treat pediatric cancers

A combination of anti-cancer antibodies produced a powerfully synergistic response in two hard-to-treat pediatric cancers, according to a new study, in mice, led by researchers at the Stanford University School of Medicine.

19 Jan 2022

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant.

18 Jan 2022

Study provides insights into how SARS-CoV-2 impacts the brain

Some patients who develop new cognitive symptoms after a mild bout of COVID have abnormalities in their cerebrospinal fluid similar to those found in people with other infectious diseases.

18 Jan 2022

Subcutaneous nanotherapy can make immunomodulation more effective in people with type 1 diabetes

Individuals living with type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence.

18 Jan 2022

COVID-19 during pregnancy may induce fetal immune response even in the absence of placental infection

SARS-CoV-2 infection during pregnancy may cause inflammatory immune responses in the fetus, even if the virus does not infect the placenta, according to a small National Institutes of Health study.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

Transmission of Omicron in a quarantine hotel between two vaccinated individuals across a corridor

A recent study has reported a community outbreak of imported SARS-CoV-2 Beta variant, owing to intra-hotel transmission in a DQH.

17 Jan 2022

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

New method may help make immunomodulation more effective in individuals with Type 1 diabetes

Individuals living with Type 1 diabetes must carefully follow prescribed insulin regimens every day, receiving injections of the hormone via syringe, insulin pump or some other device. And without viable long-term treatments, this course of treatment is a lifelong sentence.

17 Jan 2022

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

In a new study, researchers used a simple phenomenological model to investigate the role of immunocompromised hosts in SARS-CoV-2 antigenic development.

17 Jan 2022

Immune System News and Research

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

The effect of different heterologous vaccination intervention strategies on the winter 2020 COVID-19 wave in the US

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Variants of SARS-CoV-2 and preventive strategies

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

Antibody combination produces a synergistic response in difficult-to-treat pediatric cancers

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Study provides insights into how SARS-CoV-2 impacts the brain

Subcutaneous nanotherapy can make immunomodulation more effective in people with type 1 diabetes

COVID-19 during pregnancy may induce fetal immune response even in the absence of placental infection

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

Transmission of Omicron in a quarantine hotel between two vaccinated individuals across a corridor

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

New method may help make immunomodulation more effective in individuals with Type 1 diabetes

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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