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Case study sheds light on CAR-T therapy-related secondary cancers

A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.

13 Jun 2024

New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

While CAR T cell therapy has revolutionized treatment for many blood cancers, including non-Hodgkin lymphoma (NHL), many patients who receive CAR T cell therapy do not experience a long-term remission.

13 Jun 2024

New psychotherapy shows promise in reducing chronic pain for older veterans

A new study led by UCLA Health and the U.S. Veterans Affairs Office found chronic pain among older adults could be significantly reduced through a newly developed psychotherapy that works by confronting past trauma and stress-related emotions that can exacerbate pain symptoms.

13 Jun 2024

New research finds a way to delay vitamin B6 degradation

A low vitamin B6 level has negative effects on brain performance. A research team from Würzburg University Medicine has now found a way to delay the degradation of the vitamin.

13 Jun 2024

Pre-surgery GLP-1 agonists reduce post-operative risks in extreme obesity

A combination of GLP-1 agonists taken before metabolic and bariatric surgery may help patients with extreme obesity lower the risk of post-operative complications, according to a new study presented today at the American Society for Metabolic and Bariatric Surgery 2024 Annual Scientific Meeting.

13 Jun 2024

MEK inhibitor trametinib shows potential in pediatric JMML treatment

The MEK inhibitor trametinib (Mekinist) was an effective treatment for pediatric patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML) enrolled in a phase II clinical trial, with seven of 10 patients alive after a median of two years.

13 Jun 2024

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

World No Tobacco Day Panel Discussion

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From Bedfont® Scientific Ltd 13 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy - a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers - is low, despite a Food and Drug Administration warning.

12 Jun 2024

‘I try to stay strong’: Mom struggles to get diagnosis for son’s developmental problems

Four-year-old Ahmeir Diaz-Thornton couldn't sit still in class and rarely ate his lunch. While his preschool classmates spoke in perfect sentences, Ahmeir had trouble pronouncing words.

12 Jun 2024

UNF researchers awarded U.S. patent for targeted cancer-fighting compound

Three University of North Florida (UNF) researchers have been awarded a U.S. patent for a targeted cancer-fighting compound, or peptoid, that the team has discovered targets certain breast, colon and lung cancers and stops them from progressing.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

Glioblastoma multiforme (GBM) is among the most aggressive forms of brain tumors, with few effective treatment options and a bleak prognosis.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Natural antioxidants could delay age-related decline in male testosterone production

Natural polyphenolic compounds to enhance testosterone production and prevent age-related hypogonadism in aging males.

12 Jun 2024

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Jun 2024

Therapy News and Research

Case study sheds light on CAR-T therapy-related secondary cancers

New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

New psychotherapy shows promise in reducing chronic pain for older veterans

New research finds a way to delay vitamin B6 degradation

Pre-surgery GLP-1 agonists reduce post-operative risks in extreme obesity

MEK inhibitor trametinib shows potential in pediatric JMML treatment

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

World No Tobacco Day Panel Discussion

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

‘I try to stay strong’: Mom struggles to get diagnosis for son’s developmental problems

UNF researchers awarded U.S. patent for targeted cancer-fighting compound

Enhancing CAR-T cell therapy with biodegradable scaffolds

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Natural antioxidants could delay age-related decline in male testosterone production

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Study reveals unconscious fear of exercise in knee osteoarthritis patients

Attenuated virus helps eliminate cancer in mice

Revolutionary AI tool detects multiple cancers in whole-body PET/CT scans

Innovative blood test boosts accuracy of lung cancer screening

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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