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New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

A new study, published in Nano Letters, describes an effective new COVID-19 vaccine candidate based on a messenger ribonucleic acid (mRNA) platform.

28 May 2021

Researchers identify a novel SARS-CoV-2 variant (with the V1230L mutation) in West Bengal, India

Researchers analyzed 2,000 viral genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – sequences obtained from India and found a new variant that could be more infectious and transmissible.

28 May 2021

IP6 molecules are key to stabilizing and protecting retroviruses

A newly discovered molecule central to the assembly of HIV may provide valuable insight into the development and function of viruses and how to combat them.

28 May 2021

Scientists identify many new gene variants that increase risk for depression

In the largest genetic analysis of depression to date, Veterans Affairs researchers identified many new gene variants that increase the risk for depression. The groundbreaking study helps researchers better understand the biological basis of depression and could lead to better drug treatments.

28 May 2021

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

Aging published "Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial" which reported on a randomized controlled clinical trial conducted among 43 healthy adult males between the ages of 50-72.

28 May 2021

New microbial genes responsible for bile acid conversion is a major step forward for gut health

As the owner of a human body, you're carrying trillions of microbes with you everywhere you go. These microscopic organisms aren't just hitching a ride; many of them perform essential chemical reactions that regulate everything from our digestion to our immune system to our moods.

27 May 2021

Researchers use genomic sequencing technique to detect presence of various microbes

About 12,000 bacteria and viruses collected in a sampling from public transit systems and hospitals around the world from 2015 to 2017 had never before been identified, according to a study by the International MetaSUB Consortium, a global effort at tracking microbes that is led by Weill Cornell Medicine investigators.

27 May 2021

Rapid Novor First to Decode Polyclonal Antibodies Using Only Proteomics

Novel antibody discovery platform REpAb® unlocks direct access to key antibodies through next-generation protein sequencing

From Rapid Novor Inc 27 May 2021

Oligo DNA improves differentiation of skeletal muscles exacerbated by diabetes

Skeletal muscle is the largest organ in the body that accounts for 30 to 40% of body weight and is responsible for multiple functions such as energy metabolism and heat production.

27 May 2021

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Researchers in the UK, including the University of Oxford and Glasgow, as well as the University of Heidelberg, published their analysis of protein-RNA interactions in SARS-CoV-2 and the subsequent significance in the journal Molecular Cell. This research could help to uncover novel antiviral strategies for COVID-19 due to a broader understanding of how the virus works.

27 May 2021

Scientists develop new resources to combat cancer, advance cutting-edge genomics research

University of Virginia School of Medicine scientists have developed important new resources that will aid the battle against cancer and advance cutting-edge genomics research.

27 May 2021

CASdetec: new CRISPR-based SARS-CoV-2 detection platform detects nucleic acids with high sensitivity and specificity

To add to existing CRISPR-based nucleic acid detection protocols, a team of researchers recently established a new SARS-CoV-2 detection protocol based on their previously reported platform - CDetection (Cas12b-mediated DNA detection). They combined nucleic-acid amplification methods and sample treatment protocols with CDetection and established an integrated nucleic acid detection platform called CRISPR-assisted detection or CASdetec. CASdetec has a detection limit of 1×104 copies/mL for SARS-CoV-2 pseudovirus, without any observed cross-reactivity.

26 May 2021

Newly identified genetic variants play a role in bipolar disorder

Researchers from the Danish psychiatry research-project iPSYCH have contributed to identify 33 new genetic variants which, as it turns out, play a role in bipolar disorder.

26 May 2021

Researchers develop a method to detect SARS-CoV-2 and variants simultaneously

Researchers demonstrate a method of detecting the presence and mutations in the SARS-CoV-2 virus using the smaller and cheaper Oxford Nanopore sequencer, a method they believe could make pandemic surveillance faster and cheaper.

26 May 2021

New SARS-CoV-2 variants emerge among children in United States, suggests study

As the coronavirus disease 2019 (COVID-19) pandemic approaches its eighteenth month, new variants of concern (VOCs) of the causative pathogen – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – continue to emerge all over the world. A new study explores the emergence of such VOCs among young children, below 12 years of age, and the potential consequences of this phenomenon.

26 May 2021

Zoonotic and vector-borne emerging tropical diseases pose a constant threat

A recent article published in the journal Frontiers in Tropical Diseases assessed the threat of emerging zoonotic and vector-borne tropical diseases.

26 May 2021

Researchers explore mechanical properties of cellular microenvironment in the body

Cells sense and respond to the mechanical properties of the cellular microenvironment in the body. Changes in these properties, which occur in a number of human pathologies, including cancer, can elicit abnormal responses from cells.

26 May 2021

Person infected with SARS-CoV-2 can transmit infection to three to five other people

What started as the preliminary analysis of routine laboratory data has since evolved into the largest-ever study of viral load levels in patients with SARS-CoV-2.

25 May 2021

New testing protocol for SARS-CoV-2 can process thousands of samples within 48 hours

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

Research looks at viral presence around hospitalized COVID-19 patients

Researchers in Canada aimed to determine the burden of SARS-CoV-2 in the air and on surfaces in the rooms of patients hospitalized with COVID-19.

25 May 2021

Genome News and Research

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

Researchers identify a novel SARS-CoV-2 variant (with the V1230L mutation) in West Bengal, India

IP6 molecules are key to stabilizing and protecting retroviruses

Scientists identify many new gene variants that increase risk for depression

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

New microbial genes responsible for bile acid conversion is a major step forward for gut health

Researchers use genomic sequencing technique to detect presence of various microbes

Rapid Novor First to Decode Polyclonal Antibodies Using Only Proteomics

Oligo DNA improves differentiation of skeletal muscles exacerbated by diabetes

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Scientists develop new resources to combat cancer, advance cutting-edge genomics research

CASdetec: new CRISPR-based SARS-CoV-2 detection platform detects nucleic acids with high sensitivity and specificity

Newly identified genetic variants play a role in bipolar disorder

Researchers develop a method to detect SARS-CoV-2 and variants simultaneously

New SARS-CoV-2 variants emerge among children in United States, suggests study

Zoonotic and vector-borne emerging tropical diseases pose a constant threat

Researchers explore mechanical properties of cellular microenvironment in the body

Person infected with SARS-CoV-2 can transmit infection to three to five other people

New testing protocol for SARS-CoV-2 can process thousands of samples within 48 hours

Research looks at viral presence around hospitalized COVID-19 patients

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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