Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Antidepressant treatment leads to impaired empathy regarding perception of pain

Antidepressant treatment, not only depression per se, can lead to reductions in behavioral and neural responses to pain empathy

18 Jun 2019

Weighing risks and benefits of antidepressant medication for older adults

Depression is a common and serious problem for older adults. Some 15 to 20 percent of people aged 65 and older who live independently deal with symptoms of major depressive disorder.

12 Jun 2019

FDA overlooked red flags in drugmaker’s testing of new depression medicine

Ketamine is a darling of combat medics and clubgoers, an anesthetic that can quiet your pain without suppressing breathing and a hallucinogenic that can get you high with little risk of a fatal overdose.

11 Jun 2019

NIH funds clinical trials to assess applicability of genomics for treating chronic diseases

The National Institutes of Health will fund clinical trials to assess the benefits, applicability and efficacy of applying genomic medicine interventions to improve management of diseases such as high blood pressure, depression and chronic pain.

6 Jun 2019

Diabetes drug reduces anxiety-like behaviors in mice

The antidiabetic medication metformin reduces anxiety-like behaviors in male mice by increasing serotonin availability in the brain, according to a study published in JNeurosci.

From Society for Neuroscience 4 Jun 2019

Is it a feminist right to want more sex? One company thinks a pill is the answer

Studies have never defined a "normal" level of sexual desire. Despite that, there's a website and an online quiz to help you decide if you've got a problem. Called "Right to Desire," it brands libido as a feminist "right," and its home page offers the defiant, in-your-face prompt: "Yes, I want my desire back."

11 May 2019

Finnish researchers discover gene mutation that reduces fear, anxiety and increases social interaction

Finnish researchers at the University of Eastern Finland and the University of Oulu have discovered of a new type of gene mutation that reduces fear and anxiety, and increases social interaction.

3 May 2019

Researchers find potential link between autism and antidepressant use during pregnancy

An international team led by Duke-NUS Medical School has found a potential link between autistic-like behavior in adult mice and exposure to a common antidepressant in the womb.

30 Apr 2019

Researchers use nitrous oxide to unravel rapid function of antidepressant mechanisms

Ketamine is commonly used in emergency medicine as an anesthetic drug. Later it was discovered to have rapid-acting antidepressant effects, but the mechanisms by which ketamine alleviates depression are still unknown.

29 Apr 2019

Scientists develop maps of two melatonin receptors vital for sleep, other biological processes

An international team of researchers used an X-ray laser at the Department of Energy’s SLAC National Accelerator Laboratory to create the first detailed maps of two melatonin receptors that tell our bodies when to go to sleep or wake up and guide other biological processes.

26 Apr 2019

Researchers identify ketamine-induced neural changes responsible for remission of depression

Researchers have identified ketamine-induced brain-related changes that are responsible for maintaining the remission of behaviors related to depression in mice -- findings that may help researchers develop interventions that promote lasting remission of depression in humans.

12 Apr 2019

Workings of ketamine in depressive illness decoded

Researchers have now found the exact mechanism of how the drug works in the brains of individuals with depression and can keep the symptoms down for more than a week.

12 Apr 2019

Study sheds new light on long-term treatment with antidepressant drugs

A new study published in the current issue of Psychotherapy and Psychosomatics sheds new light on long-term studies with antidepressant drugs.

11 Apr 2019

Anti-inflammatory medicine can be effective in treating people with depression

The World Health Organization calls depression one of the most serious mental disorders, and researchers around the world are trying to improve treatment of the disease.

8 Apr 2019

People with treatment-resistant depression at higher risk of developing substance use syndrome

People suffering from treatment resistant depression are at a higher risk of developing substance use disorders than other patients with depression, reports a study by researchers at Karolinska Institutet in Sweden published in the journal Addiction.

2 Apr 2019

Research uncovers crucial receptor involved in response to fast-acting antidepressants

Effective treatment of clinical depression remains a major mental health issue, with roughly 30 percent of patients who do not respond to any of the available treatments.

29 Mar 2019

Prescriptions for antidepressants have doubled over the last decade says NHS report

NHS figures reveal that over the last ten years, the number of prescriptions for antidepressants has doubled. There has also been a rise in the drugs prescribed for conditions resulting from unhealthy lifestyle behaviours.

29 Mar 2019

Symptomatic pharmacotherapy of elderly people should be regularly monitored

The prevalence of using antidepressants and proton pump inhibitors increases after the diagnosis of Alzheimer’s disease, according to a doctoral dissertation from the University of Eastern Finland.

26 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019

Study provides new understanding of how the brain recovers from damage caused by stroke

Each year, approximately 265,000 Americans have a stroke that causes visual impairment. New research, which appears in the journal Proceedings of the Royal Society B, sheds light on how the damage in the brain caused by a stroke can lead to permanent vision impairment.

21 Mar 2019