Cellular Biology News and Research

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Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their scientific name and all of them have in common a phosphate part, a sugar part and a nucleobase part.

21 Jul 2014

Study provides evidence for intranasal nerve growth factor for repair of spinal cord injury

Nerve growth factor can be delivered to the brain by intranasal administration without risk for treatment of brain diseases.

21 Jul 2014

Scientists build artificial cells programmed to eat their undesirable neighbors

A team of researchers has devised a Pac-Man-style power pellet that gets normally mild-mannered cells to gobble up their undesirable neighbors. The development may point the way to therapies that enlist patients’ own cells to better fend off infection and even cancer, the researchers say. A description of the work will be published July 15 in the journal Science Signaling.

16 Jul 2014

Scientists develop RNA that binds cGMP

The transmission of signals within cells is dependent on cyclic guanosine monophosphate (cGMP) as an important secondary messenger. German scientists have now developed an RNA that binds cGMP. As reported in the journal Angewandte Chemie, it is possible to suppress the cGMP signal cascade in genetically modified cells that produce this RNA.

10 Jul 2014

Neuroprotective effects of lithium are likely related to gene expressions

Lithium, as a neuroprotective agent, benefits for neuronal survival. Recent cDNA array studies have demonstrated that mood stabilizer lithium exhibits neuroprotective effects through multiple targets.

9 Jul 2014

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Lysosomes are subcellular organelles that are present in most cells, with the major exception of red blood cells.

8 Jul 2014

Researcher describes possible implications of increased gravity effect on immunity

Before you swat away the next fruit fly, consider instead just how similar its biological complexities are to our own.

4 Jul 2014

BINDER ultra low temperature freezer provides high safety for biological samples

In the field of cell biology in particular, a wide variety of samples including nucleic acid or protein samples have to be preserved for longer periods of time. At temperatures down to – 86°C, samples often remain frozen for several weeks up to several years. 100% reliability of the cooling system is essential. Otherwise, any interruption could result in the complete loss of the research results, requiring the results to be recreated, which costs time and money.

From BINDER GmbH 3 Jul 2014

University of Louisville researchers take a step forward in battle against lung cancer

Researchers at the University of Louisville have uncovered a cadre of small molecules that tell certain proteins to kill lung cancer cells. The team, led by Chi Li, Ph.D., assistant professor of medicine, published its finding in the April 2014 issue of Molecular and Cellular Biology.

28 Jun 2014

FEI announces the sale of a complete correlative workflow to the University of Maastricht

FEI (NASDAQ: FEIC) announces the sale of a complete correlative workflow to the University of Maastricht. The systems will be installed at the University’s Institute of Nanoscopy, a new research facility that will use the high-resolution microscopes to understand the working mechanisms of protein complexes in an effort to develop new and improved treatment and prevention for disease, such as cancer and tuberculosis.

23 Jun 2014

Protein-kinase interactions offer a new way to fight antimalarial drug resistance

When it comes to the emergence of antimalarial drug resistance, it's not a question of 'if' but 'when'. In order to keep up with the quickly evolving Plasmodium parasite - the cause of malaria - new ways to treat and control the disease must be found.

9 Jun 2014

Progress in constructing protein nanomachines

A route for constructing protein nanomachines engineered for specific applications may be closer to reality.

6 Jun 2014

Scientists define genetic cause for two types of birth defects in newborn boys

Baylor College of Medicine scientists defined a previously unrecognized genetic cause for two types of birth defects found in newborn boys, described in a report published today in the journal Nature Medicine.

2 Jun 2014

Key to being a better parent is literally all in your head

Good news for Dads: Harvard researchers say the key to being a better parent is - literally - all in your head.

15 May 2014

Biochemists identify protein that can slow down growth of brain tumors in mice

Much like using dimmer switches to brighten or darken rooms, biochemists have identified a protein that can be used to slow down or speed up the growth of brain tumors in mice.

12 May 2014

Molecular imaging and multimodality: an interview with Professor Silvio Aime, University of Turin

Molecular imaging aims at the visualization of molecules or molecular events that occur at the cellular level. Clearly it also allows the possibility of looking inside the biochemical pathway at the cellular level and therefore enables us to look at the onset of diseases well before they are resolved into structural change.

From Bruker BioSpin Group 12 May 2014

Enrichment of highly abundant epigenetic marks from endometrial stromal cells

Chromatrap®, the novel solid-based matrix for chromatin immunoprecipitation (ChIP) assays, available from Porvair Sciences, has been successfully used to isolate high quality chromatin from difficult biopsy material.

From Chromatrap® - Porvair Sciences Ltd 30 Apr 2014

Decker Foundation gift helps Binghamton University to establish lab for improving health outcomes

A gift from the Dr. G. Clifford & Florence B. Decker Foundation will enable Binghamton University biologists and their colleagues to conduct tests and research that will improve health outcomes for patients in Southern Tier hospitals with conditions ranging from ear infections to cancer.

30 Apr 2014

Mother's diet before conception can permanently affect how her child's genes function

A mother's diet before conception can permanently affect how her child's genes function, according to a study published in Nature Communications.

30 Apr 2014

Bitplane present prize to Excellence Awards winner

Bitplane, an Oxford Instruments company and the world leader in 2 to 4D image visualisation, analysis and interpretation, have presented Dr Weimiao Yu with his prize for his winning entry in the inaugural Excellence Awards. Steve Chai, Bitplane, presented Dr Yu with a commemorative certificate and a MacBook Pro. Dr Yu’s winning entry focused on the analysis of cell protrusions during migration; a phenomenon that is not well understood and is thought to play a key role in immune response and metastasis formation, for example.

29 Apr 2014