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Researchers challenge the genetic paradigm of cancer

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18th in the open-access journal PLOS Biology.

19 Mar 2025

Frequently asked questions about BioAFM

Do you have a question about BioAFM? This article will tell you everything you need to know.

From Bruker BioAFM 17 Mar 2025

Breakthrough peptide inhibitor effective against multiple SARS-CoV-2 variants

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors.

14 Mar 2025

What can you do with a BioAFM instrument?

Even more answers to help understand how BioAFM can be used!

From Bruker BioAFM 14 Mar 2025

3D imaging sheds light on how nerves and blood vessels in the skull decline with age

As the body ages, bones undergo changes that can hinder their ability to regenerate and heal. While previous studies have concentrated on the structural shifts in bone tissue itself, the role of nerves and blood vessels—critical players in bone health—has remained relatively unexplored.

11 Mar 2025

PlasticHeal project sheds light on hidden health effects of nanoplastics

Microplastics and nanoplastics, two of the smallest and most invisible forms of plastic pollution, may pose risks to human health.

11 Mar 2025

Compound found in rosemary shows promise for Alzheimer's treatment

The herb rosemary has long been linked with memory: "There's rosemary, that's for remembrance," says Ophelia in Shakespeare's Hamlet. So it is fitting that researchers would study a compound found in rosemary and sage-carnosic acid-for its impact on Alzheimer's disease.

10 Mar 2025

Study uncovers how transposons use telomeres for survival in bacteria

Transposons, or "jumping genes" – DNA segments that can move from one part of the genome to another – are key to bacterial evolution and the development of antibiotic resistance.

7 Mar 2025

How tobacco and cannabis affect male fertility and genetic integrity

A study reveals cannabis and tobacco use harm sperm quality and DNA integrity, with cannabis causing greater damage, raising concerns for reproductive health.

6 Mar 2025

Scientists uncover structure of key enzyme to block cancer cell energy supply

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other resources, including a group of enzymes that help normal cells maintain a balance of energy.

6 Mar 2025

Breakthrough study sheds light on Pol-theta’s role in DNA repair and cancer

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these proteins-called polymerase theta (Pol-theta)-for their own survival.

4 Mar 2025

Engineered TIMPs show promise in fighting glioblastoma invasion

A new research paper was published in Oncotarget, Volume 16, on February 28, 2025, titled "Effect of TIMPs and their minimally engineered variants in blocking invasion and migration of brain cancer cells."

3 Mar 2025

Scientists identify Blastocystis spp. in nearly 10% of edible plants worldwide, highlighting food safety concerns

A new study finds that 9.4% of edible plants worldwide are contaminated with Blastocystis spp., highlighting food safety concerns and the need for improved agricultural hygiene.

3 Mar 2025

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

Researchers explored L-arginine-loaded lipid nanoparticles from fenugreek seed oil, finding they enhance drug stability and bioavailability, showing promise for diabetes treatment.

2 Mar 2025

AI detects colorectal cancer with high accuracy

A new AI-based tool for identifying colorectal cancer from tissue sample analysis has been developed at the University of Jyväskylä. The new artificial neural network model has surpassed all its predecessors in classification performance. The tool has also been made freely available.

28 Feb 2025

Scientists uncover how a sugar shield in brain blood vessels protects against aging and disease

Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain barrier, leading to increased permeability, neuroinflammation, and cognitive decline in aging and neurodegenerative diseases.

27 Feb 2025

Microphysiological systems in drug discovery

NewsMedical speaks with CN Bio about the translatability between in vitro organ-on-a-chip (OOC) models, microphysiological systems, and their in vivo counterparts.

From CN Bio 26 Feb 2025

New AI model revolutionizes cell structure segmentation in microscopy

Identifying and delineating cell structures in microscopy images is crucial for understanding the complex processes of life.

26 Feb 2025

Researchers discover key signaling pathway involved in atherosclerotic plaques

CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway - with therapeutic potential.

25 Feb 2025

Using bioengineered materials to treat chemotherapy-induced oral lesions

A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled "Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters' model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane."

25 Feb 2025