OCT News and Research

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Scalable synthetic biology revolutionizes targeted therapy with logic-gate proteins

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint the exact areas of the body where they're needed - and nowhere they're not - can reduce the medicine dosage and avoid potentially harmful "off target" effects elsewhere in the body.

10 Oct 2025

New gene therapy reverses symptoms of SYNGAP1-related disorders in mice

In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice.

9 Oct 2025

PAHO and OAS launch first Inter-American Mental Health Week

The Pan American Health Organization (PAHO) joins the Organization of American States (OAS) to celebrate the first ever Inter-American Mental Health Week during the second week of October.

9 Oct 2025

Third-sector services prove more effective at helping the long-term unemployed in deprived areas

New research reveals that 'third-sector' services, such as those run by housing associations, are far more effective than government work programmes at helping the long-term unemployed in deprived areas.

9 Oct 2025

Women show peak cognitive performance during ovulation but exercise matters more

Women performed best on cognitive tests during ovulation but physical activity level had a stronger influence on brain function, according to a new study from researchers at UCL.

9 Oct 2025

New blood atlas reveals how diseases leave unique protein signatures

A new study has mapped the distinct molecular "fingerprints" that 59 diseases leave in an individual's blood protein – which would enable blood tests to discern troubling signs from those that are more common.

9 Oct 2025

Cleveland Clinic team uncovers genetic link to osteosarcoma

Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.

9 Oct 2025

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumor growth.

9 Oct 2025

Nanoparticle vaccine shows promise in preventing multiple cancers in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice.

9 Oct 2025

Watching short inspirational videos provides stress relief just like meditation

Watching short inspirational videos may be just as effective at reducing stress as meditation, according to research published by the American Psychological Association.

9 Oct 2025

Quitting smoking after cancer diagnosis significantly extends survival

Around 25% of people with cancer in the U.S. are active smokers when they are diagnosed, and studies have found that many of them continue to smoke during treatment.

9 Oct 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

Study reports the world's first genetically engineered pig-to-human liver xenotransplantation

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient.

9 Oct 2025

Survey reveals strong support for patient involvement in allergy research

A team of researchers from Keio University School of Medicine, the Institute of Medical Science at the University of Tokyo, and the National Center for Child Health and Development has reported the first cross-disease, cross-stakeholder survey on PPIE in Japan.

9 Oct 2025

Research uncovers ASPL's critical role in stress granule life cycle

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked to neurodegenerative diseases.

9 Oct 2025

Researchers quantify forced labor risk in five dietary patterns

Many Americans choose food based on cost and nutrition, but personal values, such as animal welfare and environmental concerns, also shape what ends up on our plates.

9 Oct 2025

Prior incarceration linked to poor health in older adults

A recent analysis reveals that older adults with prior incarceration report worse physical and mental health than their peers, even if they were incarcerated in the distant past. The findings are published in the Journal of the American Geriatrics Society.

9 Oct 2025

Chlorinated compounds from slime mold show strong antibacterial activity

The cellular slime mold Dictyostelium discoideum is a soil microbe that produces diverse natural products with potential antibiotic activity.

9 Oct 2025

Natural sweetener improves hair loss treatment

Androgenetic alopecia is a common form of hair loss in both men and women-also called male pattern baldness and female pattern hair loss.

9 Oct 2025

Study warns of inevitable child mortality rise without unimpeded aid in Gaza

More than 54,600 children in Gaza are estimated to be acutely malnourished, including over 12,800 severely so, with few therapeutic options available to them. With measurements up to the middle of August 2025, the study comprehensively tracks wasting among children during the war, estimates population prevalence, and highlights unprecedented increases in child malnutrition following periods of blockades and severe aid restrictions.

9 Oct 2025