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Genetic culprits of idiopathic pulmonary fibrosis

Scientists at Johns Hopkins have identified the genetic culprits that trigger a hereditary form of a fatal lung disease.

30 Mar 2007

Study shows how antibiotic gentamicin affects cystic fibrosis patients with a stop mutation

Genetics tests could help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest.

30 Mar 2007

Brain's immune system plays protective role in early Alzheimer's disease

The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder.

30 Mar 2007

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.

30 Mar 2007

Withdrawal of Pergolide products

The U.S. Food and Drug Administration (FDA) today announced that manufacturers of pergolide drug products, which are used to treat Parkinson's disease, will voluntarily remove these drugs from the market because of the risk of serious damage to patients' heart valves.

29 Mar 2007

Flushing out cancerous tumours

A researcher from the University of Bradford has been awarded a grant to investigate a way of flushing out cancerous tumours in the body with no potentially harmful side-effects.

28 Mar 2007

Researchers identify key protein in immune response to malaria and TB

An international team of researchers has identified a key protein involved in the immune system's response to malaria, tuberculosis (TB) and a number of other infectious diseases. The insights suggest possible new therapies to tackle these major global diseases.

28 Mar 2007

Why better TB care in Africa is in European interests

The recent outbreak of a lethal combination of HIV and TB in southern Africa has prompted Britain to pledge an extra US$ 3.15 million to the World Health Organization's Stop TB partnership.

27 Mar 2007

Immune response to cancer stem cells may dictate cancer's course

Although stem cells hold incredible promise in the fight against certain diseases, in cancer they're anything but helpful. In fact, mounting evidence is showing that a tumor's growth and spread may depend on 'cancer stem cells,' which comprise only a very small subset of the tumor.

27 Mar 2007

Happy schools lead to lower levels of substance abuse and teen pregnancy

Promoting a positive ethos in schools, in which students are more engaged and enjoy good relationships with their teachers, can lead to lower levels of substance abuse and teen pregnancy, according to a study which appears in the British Medical Journal.

25 Mar 2007

Study describes how estradiol helps to maintain bone density

Researchers at the University at Buffalo have described a novel pathway by which estradiol, the primary estrogen in humans, aids in maintaining bone density, a function critical to avoiding osteoporosis.

25 Mar 2007

Drugs should be classified by the amount of harm that they do

A new study published in The Lancet proposes that drugs should be classified by the amount of harm that they do, rather than the sharp A, B, and C divisions in the UK Misuse of Drugs Act.

25 Mar 2007

25 per cent of new cases of schizophrenia in the UK may be due to cannabis

If cannabis causes schizophrenia - and that remains in question - then by 2010 up to 25 per cent of new cases of schizophrenia in the UK may be due to cannabis, according to a new study by Dr Matthew Hickman of the University of Bristol and colleagues, published in Addiction journal.

25 Mar 2007

Researchers look at whether creatine slows progression of Parkinson's disease

Researchers at the University of Rochester Medical Center are leading one of the largest clinical trials ever for Parkinson's disease.

25 Mar 2007

Circadian genes may be involved in bipolar disorder

Disrupt the gene that regulates the biological clocks in mice and they become manic, exhibiting behaviors similar to humans with bipolar disorder, UT Southwestern Medical Center researchers have found.

25 Mar 2007

Controlling HIV/AIDS in India - an immense challenge

Controlling HIV/AIDS in India is an "immense" challenge for the country's National AIDS Control Organization -- which is preparing to launch on April 1 the third phase of its National AIDS Control Program, a new five-year, $2.6 billion program that aims to reduce the number of new HIV cases and improve access to treatment in the country -- NEJM national correspondent Robert Steinbrook writes in a perspective piece.

22 Mar 2007

Some people with HIV/AIDS in Zambia are abandoning their antiretroviral drug regimens for ineffective cures

Some people living with HIV/AIDS in Zambia are abandoning their antiretroviral drug regimens for ineffective drugs that in recent weeks have been promoted in the media as cures for the disease, the Network of Zambian People Living with HIV and AIDS said on Monday, AFP/Independent Online reports.

22 Mar 2007

Global tuberculosis epidemic has levelled off

The global tuberculosis (TB) epidemic has levelled off for the first time since WHO declared TB a public health emergency in 1993. The Global Tuberculosis Control Report released today by WHO finds that the percentage of the world's population struck by TB peaked in 2004 and then held steady in 2005.

22 Mar 2007

Thailand, pharmaceutical companies to continue talks on compulsory drug licenses

Thai public health officials plan to continue discussions with international pharmaceutical companies following recent debates over compulsory licenses issued by the country for some medications, U.S. Chamber of Commerce Senior Vice President Daniel Christman said on Tuesday, Reuters UK reports

22 Mar 2007

Massachusetts health insurance connector board votes to require prescription drug coverage as part of draft minimum coverage requirements

The Massachusetts Commonwealth Health Insurance Connector Authority on Tuesday approved minimum coverage requirements for health insurance plans to comply with the state's universal coverage law, including requiring prescription drug coverage, the New York Times reports.

22 Mar 2007