Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

AAN, ABF and MDA offer new two-year clinical training fellowship in muscular dystrophy

The American Academy of Neurology, the American Brain Foundation and the Muscular Dystrophy Association have announced a new Clinical Research Training Fellowship in muscular dystrophy for 2017.

10 Jul 2016

AAN announces winners of 2016 Neuro Film Festival

The American Academy of Neurology is pleased to announce the winning entries to the 2016 Neuro Film Festival.

10 Jul 2016

New methods to examine the brain and spinal fluid could lead to early detection of Alzheimer's disease

New methods to examine the brain and spinal fluid heighten the chance of early diagnosis of Alzheimer's disease. Results from a large European study, led by researchers at the Karolinska Institutet, are now published in the medical journal BRAIN.

8 Jul 2016

Athletes may experience long-term brain changes after sports-related concussion

New research finds white matter changes in the brains of athletes six months after a concussion. The study will be presented at the Sports Concussion Conference in Chicago, July 8-10, hosted by the American Academy of Neurology, the world's leading authority on the diagnosis and management of sports-related concussion.

8 Jul 2016

Genetic risk score may help detect Alzheimer's disease risk in healthy young adults

New research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even possibly in healthy young adults, according to a study published in the July 6, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Jul 2016

New approach for testing safety in older adult drivers at risk of dementia

Driving is possibly one of the most complex procedures humans engage in on a regular basis.

6 Jul 2016

Rapid number naming test can detect cognitively impaired people with AD

For the first time, researchers have determined that a brief, simple number naming test can differentiate between cognitively healthy elderly individuals and cognitively impaired people with Alzheimer's disease (AD), including those with mild cognitive impairment (MCI), as well as those with AD dementia.

6 Jul 2016

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer's disease (AD).

6 Jul 2016

MorphoSys receives clinical milestone for start of Phase 1 trial in prevention of thrombosis with novel antibody

MorphoSys AG announced that it has received a milestone payment from Novartis in connection with the initiation of a clinical phase 1 trial with a novel HuCAL antibody. The antibody will be tested in the field of prevention of thrombosis. This is the twelfth therapeutic antibody based on MorphoSys's technologies that Novartis is evaluating in clinical trials. Financial details were not disclosed.

6 Jul 2016

New mouse model reveals how Alzheimer's causes dementia

Using a novel, newly developed mouse model that mimics the development of Alzheimer's disease in humans, Johns Hopkins researchers say they have been able to determine that a one-two punch of major biological "insults" must occur in the brain to cause the dementia that is the hallmark of the disease.

4 Jul 2016

Brain vessel diseases may contribute to Alzheimer's dementia

While strokes are known to increase risk for dementia, much less is known about diseases of large and small blood vessels in the brain, separate from stroke, and how they relate to dementia.

4 Jul 2016

Researchers uncover how dysfunction of brain circuit may contribute to memory loss

Two interconnected brain areas - the hippocampus and the entorhinal cortex - help us to know where we are and to remember it later.

30 Jun 2016

UTHealth researchers receive $11 million grant to study prion diseases

Led by Claudio Soto, Ph.D., researchers from McGovern Medical School at The University of Texas Health Science Center at Houston have been awarded $11 million from the National Institute of Allergy and Infectious Diseases to study the pathogenesis, transmission and detection of prion diseases - such as chronic wasting disease in deer - that can potentially spread to humans.

30 Jun 2016

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

For a promising pathway to treating Alzheimer's patients, "aim here." That's what National Institute of Standards of Technology researchers advised collaborators hunting for molecules that, by linking to a normally occurring enzyme, rev up the brain's capacity for clearing cholesterol--a boost associated with improvements in memory and other benefits in animal studies.

29 Jun 2016

Study pinpoints how PSEN1 gene mutations can cause early onset Alzheimer's disease

A University of Adelaide analysis of genetic mutations which cause early-onset Alzheimer's disease suggests a new focus for research into the causes of the disease.

27 Jun 2016

Older adults with high LDL-C live longer than peers with low levels of same cholesterol, say experts

A University of South Florida professor and an international team of experts have found that older people with high levels of a certain type of cholesterol, known as low-density lipoprotein (LDL-C), live as long, and often longer, than their peers with low levels of this same cholesterol.

27 Jun 2016

Novel combination therapy may help provide clinically successful treatment for AD

Resveratrol is a naturally occurring polyphenolic phytochemical produced in several plants, especially grapes skin and seeds. One epidemiological study reported a positive association between moderate red wine consumption and a low incidence of cardiovascular disease, known as the "French Paradox."

25 Jun 2016

Alzheimer's Disease News and Research

Further Reading

AAN, ABF and MDA offer new two-year clinical training fellowship in muscular dystrophy

AAN announces winners of 2016 Neuro Film Festival

New methods to examine the brain and spinal fluid could lead to early detection of Alzheimer's disease

Athletes may experience long-term brain changes after sports-related concussion

Genetic risk score may help detect Alzheimer's disease risk in healthy young adults

New approach for testing safety in older adult drivers at risk of dementia

Rapid number naming test can detect cognitively impaired people with AD

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

MorphoSys receives clinical milestone for start of Phase 1 trial in prevention of thrombosis with novel antibody

New mouse model reveals how Alzheimer's causes dementia

Brain vessel diseases may contribute to Alzheimer's dementia

Researchers uncover how dysfunction of brain circuit may contribute to memory loss

UTHealth researchers receive $11 million grant to study prion diseases

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

Study pinpoints how PSEN1 gene mutations can cause early onset Alzheimer's disease

Older adults with high LDL-C live longer than peers with low levels of same cholesterol, say experts

Novel combination therapy may help provide clinically successful treatment for AD

Study to assess effects of early dementia screening on families of older adults

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

Long-term suppression of neurotransmitter acetylcholine may lead to dementia-like changes in the brain

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