Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Scientists provide new insights into molecular regulation of stem cell differentiation

The findings of the scientists of the Institute of Diabetes and Regeneration Research (IDR) at Helmholtz Zentrum München (HMGU) provide new insights into the molecular regulation of stem cell differentiation.

25 Jan 2014

Diabetic British Muslims may avoid attending GP surgeries to discuss fasting during Ramadan

British Muslims with diabetes may avoid attending GP surgeries to discuss fasting during the holy month of Ramadan - with potentially serious consequences for their future health, new research by the universities of Manchester and Keele shows.

From The University of Manchester 24 Jan 2014

Statistical methods improve biological single-cell analyses

Each cell in our body is unique. Even cells of the same tissue type that look identical under the microscope differ slightly from each other.

24 Jan 2014

Study: Lingonberries completely prevented weight gain in mice fed high-fat diet

Lingonberries almost completely prevented weight gain in mice fed a high-fat diet, a study at Lund University in Sweden has found - whereas the 'super berry' açai led to increased weight gain. The Scandinavian berries also produced lower blood sugar levels and cholesterol.

24 Jan 2014

Mylan Pharmaceuticals launches Repaglinide Tablets, 0.5 mg, 1 mg and 2 mg

Mylan Inc. today announced that its U.S.-based subsidiary Mylan Pharmaceuticals Inc. has launched Repaglinide Tablets, 0.5 mg, 1 mg and 2 mg. This product is the generic version of Novo Nordisk's Prandin, which is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

24 Jan 2014

Researchers identify five new genes associated with increased waist-to-hip ratio

Excess abdominal fat can be a precursor to diseases such as cardiovascular disease, type 2 diabetes and cancer. A person's measure of belly fat is reflected in the ratio of waist circumference to hip circumference, and it is estimated that genetics account for about 30-60 percent of waist-to-hip ratio.

23 Jan 2014

Research under way to develop new techniques for detecting diabetic retinopathy

Research is under way to develop new techniques for detecting diabetic retinopathy at early onset with the hope of improving prevention and treatment of this major cause of blindness.

22 Jan 2014

UT Southwestern' faculty receives Stanley J. Korsmeyer Award for contributions to understanding of autophagy

Dr. Beth Levine, a Howard Hughes Medical Institute Investigator and Director of the Center for Autophagy Research at UT Southwestern Medical Center, has received the 2014 Stanley J. Korsmeyer Award from the American Society for Clinical Investigation.

22 Jan 2014

Trials, and a few unexpected triumphs, for insurance exchanges

A procurement document posted on a federal website gives the newest Obamacare contractor until mid-March to build the back end of healthcare.gov, predicting dire consequences if the work is not completed on time. Other media outlets report exchange developments from Maryland, Massachusetts, Missouri, North Carolina, Oregon, Wisconsin, Georgia and Minnesota.

22 Jan 2014

Novo Nordisk launches insulin delivery device NovoPen Echo in the U.S.

Novo Nordisk, a world leader in diabetes care, today announced the launch of the insulin delivery device NovoPen Echo in the United States. This is the first and only pen device available in the U.S. with half-unit dosing and a memory function that records the dose and time passed since the last injection.

From Novo Nordisk 21 Jan 2014

Home blood pressure best guide to metabolic risk

Home blood pressure is a good guide to which patients are likely to have the metabolic syndrome, say researchers.

20 Jan 2014

Eating high levels of flavonoids found in berries, tea, and chocolate offer protection from type 2 diabetes

Eating high levels of flavonoids including anthocyanins and other compounds (found in berries, tea, and chocolate) could offer protection from type 2 diabetes - according to research from the University of East Anglia (UEA) and King's College London.

20 Jan 2014

U of T researchers find no evidence to support 'blood-type' diet theory

Researchers from the University of Toronto have found that the theory behind the popular blood type diet--which claims an individual's nutritional needs vary by blood type--is not valid. The findings are published this week in PLoS One.

17 Jan 2014

Researchers managed to replicate human pancreatic beta cells in mouse model

Klaus Kaestner, PhD, professor of Genetics and postdoctoral fellow Dana Avrahami, PhD, from the Perelman School of Medicine, University of Pennsylvania, published a study this week in the Journal of Clinical Investigation, with colleague Benjamin Glaser, MD, from the Hadassah-Hebrew University Medical Center, Jerusalem, and colleagues. In this study, they were able to replicate human pancreatic beta cells - the cells in our body that produce the critical hormone insulin - in a mouse model in which donor cells were transplanted. The newly replicated cells retained features of mature beta cells and showed a physiological response to glucose.

17 Jan 2014

Research shows biological link between paternal diet and health of offspring

Research involving rats suggests that there is a biological link between paternal diet, bodyweight and health at the time of conception and the health of his offspring. In a new research report published online in The FASEB Journal, scientists show that if male rats ate a high fat diet, had diabetes and were obese, their offspring had altered gene expression in two important metabolic tissues--pancreas and fat (even though they were not yet obese).

16 Jan 2014

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

A Montr-al research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in today's printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk.

15 Jan 2014

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

AstraZeneca and Bristol-Myers Squibb Company announced the U.S. Food and Drug Administration approved Farxiga™ [far-SEE-ga] (dapagliflozin), a once-daily oral treatment indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

13 Jan 2014

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.

13 Jan 2014

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Researchers at Joslin Diabetes Center have discovered that a hormone long associated with weight loss and improved glucose metabolism is linked to activation of calorie-burning brown fat.

10 Jan 2014

Insulin News and Research

Further Reading

Scientists provide new insights into molecular regulation of stem cell differentiation

Diabetic British Muslims may avoid attending GP surgeries to discuss fasting during Ramadan

Statistical methods improve biological single-cell analyses

Study: Lingonberries completely prevented weight gain in mice fed high-fat diet

Mylan Pharmaceuticals launches Repaglinide Tablets, 0.5 mg, 1 mg and 2 mg

Researchers identify five new genes associated with increased waist-to-hip ratio

Research under way to develop new techniques for detecting diabetic retinopathy

UT Southwestern' faculty receives Stanley J. Korsmeyer Award for contributions to understanding of autophagy

Trials, and a few unexpected triumphs, for insurance exchanges

Novo Nordisk launches insulin delivery device NovoPen Echo in the U.S.

Home blood pressure best guide to metabolic risk

Eating high levels of flavonoids found in berries, tea, and chocolate offer protection from type 2 diabetes

U of T researchers find no evidence to support 'blood-type' diet theory

Researchers managed to replicate human pancreatic beta cells in mouse model

Research shows biological link between paternal diet and health of offspring

New study examines factors that may lead to end stage renal disease

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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