Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Drugs to treat cancer and Alzheimer's disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible "pockets" with a specific, well-defined structure.

6 Jun 2016

NMNAT2 enzyme may help protect against debilitating effects of neurodegenerative disorders

A study led by biomedical researchers at Indiana University has found evidence that an enzyme known as NMNAT2 may help protect against the debilitating effects of certain degenerative brain diseases, including Alzheimer's.

3 Jun 2016

New dietary supplement can prevent, reverse massive brain cell loss

A dietary supplement containing a blend of thirty vitamins and minerals--all natural ingredients widely available in health food stores--has shown remarkable anti-aging properties that can prevent and even reverse massive brain cell loss, according to new research from McMaster University.

3 Jun 2016

Johns Hopkins study highlights added risks of undiagnosed dementia in older adults

A Johns Hopkins study on data from more than 7,000 older Americans has found that those who show signs of probable dementia but are not yet formally diagnosed are nearly twice as likely as those with such a diagnosis to engage in potentially unsafe activities, such as driving, cooking, and managing finances and medications.

2 Jun 2016

GET.ON online training course can effectively reduce depression risk

Inspired by promising tests of web-based health intervention measures, the researchers aimed to find out whether the risk of developing depression could be reduced by a six-week online training course called GET.ON. GET.ON is based on established therapy methods involving systematic problem solving and behavioural activation.

2 Jun 2016

Study finds beer consumption may protect against Aβ aggregation in the brain

While most people will agree that excessive consumption of alcohol can have a detrimental effect on the brain, there is less agreement regarding the effects of light or moderate drinking.

2 Jun 2016

Infection may trigger development of Alzheimer's disease

A growing body of research on Alzheimer's disease suggests an infectious trigger for the development of the disease. According to Brian Balin, PhD, professor of pathology and chair of bio-medical sciences at Philadelphia College of Osteopathic Medicine, this could be the key to stopping the destructive process of Alzheimer's before it even starts.

2 Jun 2016

Study shows women with migraine history have rapid decline in estrogen levels

Researchers have long known that sex hormones such as estrogen play a role in migraine. But there's been little research on how that works. Do women with migraine have higher estrogen levels in general? Higher levels at the peak of the monthly cycle?

2 Jun 2016

New roadmap can help guide researchers to speed up biomarker-based research on Alzheimer's disease

Biomarkers could revolutionise the early detection of and therapy for Alzheimer's disease. However, experts attending the Congress of the European Academy of Neurology in Copenhagen criticized that the big breakthroughs are slow in coming because of a lack of priorities in research.

1 Jun 2016

Brain scan combined with long-term memory test could help early Alzheimer's diagnosis

People with Alzheimer's disease could benefit from earlier diagnosis if a long-term memory test combined with a brain scan were carried out, a study suggests.

1 Jun 2016

Toxic substance acrolein may play role in preventing fibrillation linked to Alzheimer's disease

Scientists from RIKEN in Japan have discovered that acrolein—a toxic substance produced in cells during times of oxidative stress—in fact may play a role in preventing the process of fibrillation, an abnormal clumping of peptides that has been associated with Alzheimer's disease and other neural diseases.

1 Jun 2016

Study provides new insights into molecular basis of CaSR-related human diseases

A study led by researchers at Georgia State University provides new insights into the molecular basis of human diseases resulting from mutations in the calcium-sensing receptor (CaSR), a protein found in cell membranes.

1 Jun 2016

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer.

1 Jun 2016

Need for standardised guidelines to fight Alzheimer's disease

Some 47 million people worldwide suffer from some form of dementia. Scientists are working feverishly to find a cure for the most common form, Alzheimer's. At the Congress of the European Academy of Neurology in Copenhagen, Prof Gunhild Waldemar issued an appeal for researchers to work together and draw up standardised guidelines for early identification and treatment of the disease.

31 May 2016

Researchers detect blood-brain barrier leakage in people with early AD using contrast-enhanced MRI

Researchers using contrast-enhanced MRI have identified leakages in the blood-brain barrier (BBB) of people with early Alzheimer's disease (AD), according to a new study published online in the journal Radiology. The results suggest that increased BBB permeability may represent a key mechanism in the early stages of the disease.

31 May 2016

New tool that simulates user interaction can help develop accessible ICT applications for people with disabilities

A tool developed by researchers from UPM allows us to assess usability during the design and testing process of accessible ICT-based applications.

28 May 2016

Research sheds new light on biological processes underlying neurodegeneration in AD

Progranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal theme shared across several common neurodegenerative diseases.

26 May 2016

Specific immune system genes may determine how long people can live with glioblastoma

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain.

26 May 2016

Alzheimer’s research raises questions on the role of infection

A new study has shown that A-beta (Aβ), the protein that forms β-amyloid plaques in Alzheimer’s disease, is a normal part of the immune system - raising questions about the role infection plays in Alzheimer’s disease and whether current treatment strategies should be changed.

26 May 2016

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

A new study from örebro University, published in Science Signaling today, shows that heart medication reduces the build-up of plaque in the brain's blood vessels in mice. The question is if this is true also in humans? If the answer is yes, it might bring scientists a step closer to developing a medicine against Alzheimer's disease.

25 May 2016

Alzheimer's Disease News and Research

Further Reading

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

NMNAT2 enzyme may help protect against debilitating effects of neurodegenerative disorders

New dietary supplement can prevent, reverse massive brain cell loss

Johns Hopkins study highlights added risks of undiagnosed dementia in older adults

GET.ON online training course can effectively reduce depression risk

Study finds beer consumption may protect against Aβ aggregation in the brain

Infection may trigger development of Alzheimer's disease

Study shows women with migraine history have rapid decline in estrogen levels

New roadmap can help guide researchers to speed up biomarker-based research on Alzheimer's disease

Brain scan combined with long-term memory test could help early Alzheimer's diagnosis

Toxic substance acrolein may play role in preventing fibrillation linked to Alzheimer's disease

Study provides new insights into molecular basis of CaSR-related human diseases

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Need for standardised guidelines to fight Alzheimer's disease

Researchers detect blood-brain barrier leakage in people with early AD using contrast-enhanced MRI

New tool that simulates user interaction can help develop accessible ICT applications for people with disabilities

Research sheds new light on biological processes underlying neurodegeneration in AD

Specific immune system genes may determine how long people can live with glioblastoma

Alzheimer’s research raises questions on the role of infection

Mice study shows heart medication helps reduce build-up of plaque in brain's blood vessels

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