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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

The generation of SARS-CoV-2 virus-like particles in insect cells

Researchers have reported the development of a promising COVID-19 vaccine candidate which is based on SARS-CoV-2 VLPs, derived from the co-expression of the spike, membrane, and envelope structural proteins in the baculovirus expression system.

2 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Studies identify two groups of first-year residents who may be at risk of developing mental health issues

The first year of medical training after medical school brings intense stress, long work hours, irregular sleep schedules, and a risk of new or worsened symptoms of depression.

29 Apr 2022

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.

29 Apr 2022

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

All humans carry genetic variations in their DNA, called Single Nucleotide Polymorphisms (SNPs) that can underlie susceptibility to diseases such as diabetes and cancer.

28 Apr 2022

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond to the environment and integrate the signals from outside with endogenous developmental programs.

28 Apr 2022

Specific genes that play important role in schizophrenia identified

Schizophrenia is a serious psychiatric disorder that starts in late adolescence or early adulthood and affects around 1 in 300 people worldwide, according to the World Health Organization.

28 Apr 2022

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

Researchers at Ural Federal University have proposed the use of polyoxometallate nanoclusters as a carrier for chemotherapy drug. It will help to deliver medications precisely to the focus of a pathological process, such as a cancerous tumor, without toxic effects on healthy cells.

28 Apr 2022

New insights into how NANOG protein facilitates the activation of human cell pluripotency

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function.

28 Apr 2022

Introducing Tecan’s MagicPrep™ NGS – the walkaway solution for your NGS library prep needs

Tecan has launched the MagicPrep NGS, an automated benchtop library preparation system that transforms time-consuming and error-prone procedures into a simple, robust experience.

From Tecan 28 Apr 2022

Study shows how DNA changes in Barrett's esophagus cells may predict esophageal cancer

More and more mutations clutter up our DNA as we age. Mostly, these don't cause problems. But sometimes, a switch will flip, and a mutated cell turns cancerous. Can we see this shift in time to prevent or treat cancer before it starts?

28 Apr 2022

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

New insights could lead to better treatments for Dravet syndrome and related conditions

Children with Dravet syndrome, a severe form of epilepsy that begins in infancy, experience seizures, usually for their entire life.

27 Apr 2022

Misexpression of non-cardiac genes may lead to congenital heart disease

Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

27 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Researchers revealed that native FokI relaxation might be induced, resulting in FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids.

27 Apr 2022

DNA News and Research

Further Reading

The generation of SARS-CoV-2 virus-like particles in insect cells

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Studies identify two groups of first-year residents who may be at risk of developing mental health issues

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

Specific genes that play important role in schizophrenia identified

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

New insights into how NANOG protein facilitates the activation of human cell pluripotency

Introducing Tecan’s MagicPrep™ NGS – the walkaway solution for your NGS library prep needs

Study shows how DNA changes in Barrett's esophagus cells may predict esophageal cancer

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

New insights could lead to better treatments for Dravet syndrome and related conditions

Misexpression of non-cardiac genes may lead to congenital heart disease

Penn scientists discover how one inflammatory disorder increases susceptibility to another

Genetic cause of lupus identified

Eukaryotes emerged in a no-oxygen environment in the ocean, research suggests

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Understanding the DNA Damage Response in Innate Immunity eBook

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