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New AGA report details effectiveness and safety of fecal microbiota transplantation

Today, the American Gastroenterological Association released the first results from the NIH-funded AGA Fecal Microbiota Transplantation National Registry, the largest real-world study on the safety and effectiveness of FMT.

1 Oct 2020

Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

In many patients with Crohn's disease, abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to "creep" through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery.

1 Oct 2020

New commitments from governments and organizations support a unified approach to end pandemic

New commitments from governments, international organizations and the private sector support unified approach to end pandemic, backing a response of unprecedented scale, scope and speed - through the Access to COVID-19 Tools Accelerator - as pandemic claims more than 1 million lives

1 Oct 2020

Researchers identify a promising method to treat multiple sclerosis

Seema Tiwari-Woodruff, a professor of biomedical sciences in the School of Medicine at the University of California, Riverside, and her colleagues have received a grant of $373,000 from the National Multiple Sclerosis Society for a project in which her lab will select the five best candidate compounds to speed up nerve impulses, a promising new avenue to treat multiple sclerosis.

1 Oct 2020

NIH awards grants for using bioengineered models to improve clinical trial design

Clinical Trials on a Chip researchers plan to build and test common and rare disease models to help improve the clinical trial process.

30 Sep 2020

New trial to evaluate anti-TNF drug as a treatment for COVID-19 patients begins

Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes.

30 Sep 2020

Discovery of high affinity binders for SARS-CoV-2 spike protein

An exciting, 'tour-de-force' paper by researchers from the Massachusetts Institute of Technology describes de novo discovery of high-affinity peptide binders for SARS-CoV-2 spike glycoprotein, which opens the door for the development of rapid viral identification or conjugates for virus-directed delivery of therapeutics.

30 Sep 2020

Researchers develop research model to understand the impact of coronavirus on lungs

Scientists at Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the Center for Regenerative Medicine (CReM) joined forces to develop the most relevant research model possible for understanding how the coronavirus virus impacts the lungs, by engineering living, "breathing" human lung cells from stem cells for the task.

30 Sep 2020

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology.

30 Sep 2020

Dartmouth launches new initiative for innovations in cancer care

Five Dartmouth College alumni and health care investors have committed a total of $1.4 million in gifts to launch the Dartmouth Innovations Accelerator for Cancer.

29 Sep 2020

Researchers use fruit fly to develop a novel disease model for Pitt-Hopkins syndrome

The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a novel disease model for Pitt-Hopkins syndrome (PTHS).

29 Sep 2020

A special issue on the emerging COVID-19 infection

Acta Pharmaceutica Sinica B publishes special issue on 'Research on Emerging COVID-19 (Target, Mechanism, and Therapeutics)' edited by Hai-Bin Luo, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China; Shilin Chen, Institute of Chinese Materia Medica, Beijing, China and Peiqing Liu, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.

29 Sep 2020

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

A set of agreements to make available, for low and middle-income countries, affordable, high-quality COVID-19 antigen rapid tests were today announced by the Access to COVID-19 Tools (ACT) Accelerator.

28 Sep 2020

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

A team of scientists at the University of Groningen, in the Netherlands, demonstrates that a natural plant product, resveratrol, and its structural analog, pterostilbene, have long-lasting antiviral effects against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Study finds new treatment approach for patients with salt sensitive hypertension

High blood pressure (hypertension) affects one in two U.S. adults and can cause hardening and thickening of the arteries (atherosclerosis), which can lead to heart attacks, strokes or other complications including chronic kidney disease.

28 Sep 2020

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

An international team of researchers has found that selpercatinib, a drug that precisely targets cancers driven by mutations or alterations in the gene RET, was effective at shrinking tumours in patients with nonsmall cell lung cancer (NSCLC), with a majority of patients living for more than a year without disease progression.

28 Sep 2020

Study identifies potential drug target for dangerous E. coli infections

Escherichia coli, known as E. coli, are bacteria which many people associate with causing mild food poisoning, but some types of E. coli can be fatal.

25 Sep 2020

Researchers advance novel compounds to help treat C. difficile infection

Clostridioides difficile, or C. diff, is the leading cause of health care-associated infection in the U.S.

25 Sep 2020

Therapeutics News and Research

New AGA report details effectiveness and safety of fecal microbiota transplantation

Scientists map genetic networks that control the biology of regulatory T cells

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

New commitments from governments and organizations support a unified approach to end pandemic

Researchers identify a promising method to treat multiple sclerosis

NIH awards grants for using bioengineered models to improve clinical trial design

New trial to evaluate anti-TNF drug as a treatment for COVID-19 patients begins

Discovery of high affinity binders for SARS-CoV-2 spike protein

Researchers develop research model to understand the impact of coronavirus on lungs

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Dartmouth launches new initiative for innovations in cancer care

Researchers use fruit fly to develop a novel disease model for Pitt-Hopkins syndrome

A special issue on the emerging COVID-19 infection

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Study finds new treatment approach for patients with salt sensitive hypertension

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

Study identifies potential drug target for dangerous E. coli infections

Researchers advance novel compounds to help treat C. difficile infection

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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