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Interactive web portal details the extent of splicing events in noncoding sequences

An online tool reveals the extent of gene-restructuring events in noncoding sequences.

30 May 2022

Discovery of new prostate cancer subtype opens the door to development of therapies

Researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have identified a previously unrecognized form of hormone therapy-resistant prostate cancer, as well as a set of molecules that drive its growth.

27 May 2022

Diabetes drug can improve the efficiency and efficacy of antibacterial treatments

Old dogs may not learn new tricks, but old drugs can, according to a research team based in China. The collaboration found that Metformin, a small molecule drug that has been used to treat type II diabetes for more than 50 years, can improve the efficiency and efficacy of antibacterial treatments for quick wound-healing in mice.

27 May 2022

New approach could treat brain tumors and also prevent or delay recurrences

Scientists at the University of Michigan Rogel Cancer Center were optimistic when they identified a small molecule that blocked a key pathway in brain tumors.

27 May 2022

Scientists unlock a new approach to kill hard-to-treat cancers

In a paper appearing in Nature today, an international group of scientists have unlocked a new way to kill hard to treat cancers. These tumors resist current immunotherapies, including those using Nobel Prize winning check-point blocking antibodies.

26 May 2022

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Investigators have discovered the mechanisms underlying a T-cell receptor's immunosuppressive function, according to a study published Nature Immunology, findings that may provide insight into the development of novel precision therapeutics for chronic diseases, including cancer.

25 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

25 May 2022

Study shows potential role for MRI with DWI in surveillance protocols after pancreatic cancer resection

According to ARRS' American Journal of Roentgenology, adding diffusion-weighted MRI (DWI) to conventional MRI improves the differentiation of locally recurrent tumor and post-surgical fibrosis after pancreatic ductal adenocarcinoma (PDAC) resection, primarily due to improved sensitivity for recurrence.

25 May 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Novel mechanism to turn on cancer-killing T cells identified

Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body's own immune system to treat disease.

25 May 2022

Case Western Reserve signs license agreement to bring groundbreaking AI for helping cancer patients

When Case Western Reserve University research showed that artificial intelligence (AI) could identify which lung cancer patients would benefit from chemotherapy, a national magazine called the finding one of the "10 Most Incredible Medical Breakthroughs of 2018."

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Study estimates $1.8 billion in Medicare spending on drugs with accelerated approval

The U.S. federal government spent an estimated $1.8 billion in Medicare funds in 2019 on drugs whose clinical benefits have yet to be confirmed by the Food and Drug Administration, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health suggests.

24 May 2022

Tumor News and Research

Interactive web portal details the extent of splicing events in noncoding sequences

Discovery of new prostate cancer subtype opens the door to development of therapies

Diabetes drug can improve the efficiency and efficacy of antibacterial treatments

New approach could treat brain tumors and also prevent or delay recurrences

Scientists unlock a new approach to kill hard-to-treat cancers

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

The role of pyroptosis in COVID-19

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

Study shows potential role for MRI with DWI in surveillance protocols after pancreatic cancer resection

NYU Abu Dhabi research could pave the way for more effective cancer treatments

Novel mechanism to turn on cancer-killing T cells identified

Case Western Reserve signs license agreement to bring groundbreaking AI for helping cancer patients

New imaging approach helps scientists build a complete picture of brain networks

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Study estimates $1.8 billion in Medicare spending on drugs with accelerated approval

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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