Immune System News and Research

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Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

30 Nov 2021

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Immunotherapies have shown striking clinical benefit in the treatment of many cancers, especially when used in combination with chemotherapy.

30 Nov 2021

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Ever since the first barcode appeared on a pack of chewing gum in 1974, the now-ubiquitous system has enabled manufacturers, retailers and consumers to quickly and effectively identify, characterize, locate and track products and materials.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

In mice with high-risk neuroblastoma, tumors disappeared in response to a new combination treatment with precision medicines, a recent study from University of Gothenburg researchers shows.

30 Nov 2021

New strategy for antibodies to distort viruses discovered

It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells.

30 Nov 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

Scientists identify a new therapeutic target for HIV

Scientists in Montreal and London have identified the key role played by transcription factorRORC2 in HIV infection: the molecule attaches itself to parts of the virus's genome yet doesn't prevent it from replicating.

30 Nov 2021

Johannes Gutenberg University Mainz participates in new Collaborative Research Center

The German Research Foundation has approved the establishment of a new Collaborative Research Center in the field of materials science, in which Johannes Gutenberg University Mainz is participating with a pioneering subproject. In addition, an existing CRC coordinated by JGU was approved for a further funding period of four years.

30 Nov 2021

Virginia Tech researchers discover potential target for diagnosing and treating Lyme disease

You don't have to go far to find ticks. Just step outside and look for some grass. Look to the top of the shiny, green blade – usually ankle high. A tick might be there, waiting.

30 Nov 2021

COVID-19 infections in the fully vaccinated are rare but are common in people with weak immune systems

A real-world retrospective cohort study involving nearly 1.2 million people shows COVID-19 infections in the 'fully' vaccinated are rare but are more common and severe in people with weaker immune systems.

30 Nov 2021

Improving access to health care is key to reducing HIV incidence

Many patients living with HIV in rural Africa are not receiving regular treatment, despite recent efforts to increase access to health care across the continent.

30 Nov 2021

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

A research team at the University of Córdoba is studying the alterations that occur in the immune system's T lymphocytes with respect to age and in relation to the cytomegalovirus herpesvirus.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

SARS-CoV-2 can directly invade human kidney cells, research shows

Up to 25% of patients' COVID-19 cases involve acute kidney injury—the kidneys' equivalent of a heart attack.

29 Nov 2021

Identifying the spread of novel B.1.1.523 SARS-CoV-2

In their recent study, researchers from Lithuania have reported the emergence of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant lineage B.1.1.523 containing a set of mutations associated with immune escape, including deletion 156_158del, substitution E484K and S494P in Spike (S) protein.

28 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field.

25 Nov 2021

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

25 Nov 2021

Immune System News and Research

Novel anti-inflammatory drug target identified by CRISPR

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

New strategy for antibodies to distort viruses discovered

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

Scientists identify a new therapeutic target for HIV

Johannes Gutenberg University Mainz participates in new Collaborative Research Center

Virginia Tech researchers discover potential target for diagnosing and treating Lyme disease

COVID-19 infections in the fully vaccinated are rare but are common in people with weak immune systems

Improving access to health care is key to reducing HIV incidence

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

SARS-CoV-2 can directly invade human kidney cells, research shows

Identifying the spread of novel B.1.1.523 SARS-CoV-2

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

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