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Discovery reveals why newer PD-1 targeted therapies sometimes fail

Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies.

23 Oct 2019

Healthy behavior must be established earlier in life to improve health in old age

Reduced food intake helps both animals and humans to improve health in old age and can prolong life.

23 Oct 2019

Half the drugs in use damage gut bacteria, says new study

A startling presentation at UEG Week 2019, in Barcelona, reveals that the gut microbiome is at high risk for damage each time we use a drug from one or more of 18 commonly used groups. The effects may range from changes in the relative proportions of different beneficial and potentially harmful species to alterations in the cellular metabolism of the bacteria themselves.

23 Oct 2019

ASTRO and ACR release updated practice parameters for radiation therapy

The American Society for Radiation Oncology and the American College of Radiology recently released seven updated practice parameters for medical providers who use radiation therapy to treat patients with cancer.

22 Oct 2019

High glucose impairs circadian clock function, may increase cardiovascular risk

High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk of cardiovascular disease, scientists say.

22 Oct 2019

Researchers develop simple, low-cost way to predict preeclampsia

Australian researchers have developed a way to predict the onset of a deadly pregnancy condition that kills 76,000 women and half a million babies each year, mostly in developing countries.

22 Oct 2019

Neutrophil extracellular traps could cause organ damage in malaria

Malaria is one of the world's deadliest infectious diseases: a small mosquito bite delivers numerous malaria parasites into the bloodstream. The human body defends itself valiantly against the parasite, which usually results in periodic flu-like symptoms and severe fever. Severe cases of the disease are accompanied by tissue damage and result in potentially fatal organ failure.

21 Oct 2019

Binghamton biomedical professor receives $1.2 million in grants toward diabetes cure

A biomedical engineering professor at Binghamton University, State University of New York is trying to find a cure for diabetes from several different angles, and three federal grants totaling nearly $1.2 million will aid her and her research team in that quest.

21 Oct 2019

Systematic review: Medical marijuana shows early promise to lessen opioid use

Medical marijuana shows early promise to lessen opioid use and potential abuse, suggests a systematic review of published studies being presented at the ANESTHESIOLOGY 2019 annual meeting.

20 Oct 2019

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according to new UCLA research.

18 Oct 2019

Research could lead to new ways to fight against schistosomiasis

Scientists at the Morgridge Institute for Research have isolated a natural chemical that acts as a potent kryptonite against schistosomes, the parasitic worms that burrow through human skin and cause devastating health problems.

17 Oct 2019

Substance use disorder can complicate postoperative valvular heart disease, shows study

Patients who suffer from infective endocarditis (IE) and struggle with substance use disorder (SUD) have a 240% increased risk of dying within 6 months to 5 years after valve surgery compared to other IE patients, according to a study published online today in The Annals of Thoracic Surgery.

17 Oct 2019

Study shows why fatty liver disease contributes to increase in liver cancer

Fatty liver disease is contributing to an increase in liver cancer and basic scientists at The University of Texas Health Science at Houston have new insight as to why.

16 Oct 2019

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

Researchers identify circuit that links cigarette smoking and risk of developing diabetes

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a circuit in rats that links cigarette smoking and the risk of developing type 2 diabetes, according to a study featured on the cover of the October 17 issue of Nature.

16 Oct 2019

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

The National Institutes of Health has awarded a Michigan State University researcher a $2.1 million, five-year grant to search vast databases of existing drugs.

16 Oct 2019

New discovery paves way for better treatment of diabetes

Insulin, a hormone essential for regulating blood sugar and lipids, is normally produced by pancreatic β cells. In many people with diabetes, however, pancreatic cells are not (or no longer) functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections.

16 Oct 2019

UTEP awarded $19.2 million NIH grant to study cancer affecting Mexican-American population

The University of Texas at El Paso's Border Biomedical Research Center will accelerate its quest to understand and identify the reasons for Hispanic cancer health disparities and its ultimate impact on the people of the Paso del Norte region thanks to a five-year, $19.2 million grant from the National Institutes of Health.

16 Oct 2019

Machine learning system may offer warnings about negative side effects of drug-drug interactions

The more medications a patient takes, the greater the likelihood that interactions between those drugs could trigger negative side effects, including long-term organ damage and even death.

15 Oct 2019

Drug-light combination could offer better control over CAR T-cell treatments

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control.

15 Oct 2019

Liver News and Research

Discovery reveals why newer PD-1 targeted therapies sometimes fail

Healthy behavior must be established earlier in life to improve health in old age

Half the drugs in use damage gut bacteria, says new study

ASTRO and ACR release updated practice parameters for radiation therapy

High glucose impairs circadian clock function, may increase cardiovascular risk

Researchers develop simple, low-cost way to predict preeclampsia

Neutrophil extracellular traps could cause organ damage in malaria

Binghamton biomedical professor receives $1.2 million in grants toward diabetes cure

Systematic review: Medical marijuana shows early promise to lessen opioid use

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Research could lead to new ways to fight against schistosomiasis

Substance use disorder can complicate postoperative valvular heart disease, shows study

Study shows why fatty liver disease contributes to increase in liver cancer

Study reveals new and surprising function of adenine nucleotide translocator

Researchers identify circuit that links cigarette smoking and risk of developing diabetes

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

New discovery paves way for better treatment of diabetes

UTEP awarded $19.2 million NIH grant to study cancer affecting Mexican-American population

Machine learning system may offer warnings about negative side effects of drug-drug interactions

Drug-light combination could offer better control over CAR T-cell treatments

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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