Precision Medicine News and Research

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Scaling 3D biology: Automation, imaging, and the future of high-throughput research

Discover how 3D biology, automation, and AI are revolutionizing drug discovery, improving predictive accuracy, and accelerating research.

From Molecular Devices UK Ltd 12 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

Brain-computer interfaces signal a new era in neurosurgery and neurorehabilitation

Brain-computer interface (BCI) technology is opening an unprecedented chapter in human-machine integration by establishing direct communication between the brain and external devices.

10 Jun 2025

AI agent shows promise to support oncologists in everyday clinical practice

Clinical decision-making in oncology is challenging and requires the analysis of various data types – from medical imaging and genetic information to patient records and treatment guidelines.

6 Jun 2025

Y chromosome loss linked to poor cancer outcomes

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

4 Jun 2025

Ochsner Health shares roadmap for pharmacogenomics integration into clinical practice

In a report recently published in the American Journal of Health-System Pharmacy, the Ochsner Health system delves into the multifaceted implementation of pharmacogenomics-a rapidly evolving field that examines how genetics influence individual responses to medication.

3 Jun 2025

Clairity BREAST receives FDA authorization for AI-based breast cancer risk prediction

Clairity, Inc., a digital health innovator advancing AI-driven healthcare solutions, has received U.S. Food and Drug Administration (FDA) De Novo authorization for CLAIRITY BREAST, a novel, image-based prognostic platform designed to predict five-year breast cancer risk from a routine screening mammogram.

3 Jun 2025

US funding freeze halts malaria prevention and genomic research

The “catastrophic” freeze on US funding for malaria has halted prevention programmes across Africa and also threatens to stall advances in genomic research, says Jane Carlton, director of the Johns Hopkins Malaria Research Institute.

1 Jun 2025

Treatment switching guided by liquid biopsy results improves outcomes in advanced breast cancer

A large prospective, randomized clinical trial in patients with advanced breast cancer has found that the use of liquid biopsy blood tests for early detection of a treatment-resistance mutation, followed by a switch to a new type of treatment, substantially extends the period of tumor control compared to standard care.

1 Jun 2025

Gene expression study reveals clues to asbestos-linked mesothelioma

Gene expression leading to alterations in the DNA caused by asbestos exposure may explain the development of Malignant Pleural Mesothelioma (MPM), a rare and aggressive cancer.

31 May 2025

TTF1 identified as key biomarker for advanced KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was predictive of survival outcomes for patients with advanced KRAS G12C-mutated non-small cell lung cancer (NSCLC), following treatment with the KRAS targeted therapy sotorasib.

30 May 2025

What drives insulin resistance? Proteomics reveals key pathways in human skeletal muscle

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes therapies based on molecular profiles.

30 May 2025

Alcohol abuse drug may mitigate trauma-induced damage, especially in females

Runaway cell death and inflammation triggered by severe trauma may be interrupted by a drug used to prevent alcohol abuse – and it may be particularly effective in females, according to new research led by University of Pittsburgh School of Medicine surgeon-scientists and published today in Science Translational Medicine.

28 May 2025

Maternal warmth in early childhood shapes health through social safety

Parental warmth and affection in early childhood can have life-long physical and mental health benefits for children, and new UCLA Health research points to an important underlying process: children's sense of social safety.

28 May 2025

Firmicutes bacteria can help maintain bone mass, study suggests

A recent study involving 684 Chinese adults has uncovered a significant connection between gut microbiota, aging, and bone health, particularly in relation to osteoporosis, a condition that weakens bones and increases the risk of fractures.

27 May 2025

Scientists discover unique molecular fingerprints of insulin resistance

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

27 May 2025

Metagenomic next-generation sequencing improves pulmonary infection diagnosis

A recent study on the application of Metagenomic next-generation sequencing (mNGS) found that mNGS can achieve early detection of pathogens and accelerate the development of targeted anti-infection treatment plans, thereby improving treatment outcomes and patient prognosis.

23 May 2025

Experimental ALS drug shows unprecedented recovery in some patients

When Columbia neurologist and scientist Neil Shneider speaks to his ALS patients who volunteer for experimental therapies, he's unwaveringly honest.