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Scientists enhance the anti-cancer properties of a digitalis, a drug commonly used to treat heart disease

Employing a simple new technique to manipulate the sugars that power many front-line drugs, a team of Wisconsin scientists has enhanced the antic-cancer properties of a digitalis, a drug commonly used to treat heart disease.

9 Aug 2005

U.S. drug makers up in arms over info on FDA "Drug Watch" web page

Pharmaceutical companies in the United States are up in arms over plans by U.S. regulators to release preliminary information, about the potential side effects of drugs.

9 Aug 2005

Testing for the activity of certain genes can predict response to chemotherapy for breast cancer

Breast cancer patients could find out whether they will respond positively to chemotherapy treatment by testing for the activity of certain genes.

9 Aug 2005

DDT resistance in flies carries no cost

For those concerned with the troublesome effects of genetic resistance to drugs and pesticides, the conventional wisdom of evolution offers a reassuring word: In the absence of the original chemical threat, most resistance mutations would cause a disadvantage to their hosts and might be expected to quickly leave the genetic landscape once the use of a drug or insecticide is suspended or withdrawn.

9 Aug 2005

Mosquitoes are most attracted to children infected with malarial parasite

Malaria remains a devastating problem in Africa and understanding the factors affecting its transmission remains a crucial part of the effort to combat the disease.

9 Aug 2005

Resistance to antituberculosis drugs has been rising in Botswana since 1995

Resistance to antituberculosis drugs has been rising in Botswana since 1995, concludes a Research Letter in this weeks issue of The Lancet. Enhanced interventions for TB control are urgently needed in Botswana to prevent further emergence of drug resistance, state the authors.

4 Aug 2005

Australian researchers have found a toxin that plays an important role in the progression of Alzheimer's disease

The research, which is led by two University of New South Wales academics, is significant because drugs that are in the advanced developmental phase for other conditions might be able to be used on Alzheimer's patients, to halt the disease progressing.

4 Aug 2005

Flu medication VIRA 38 inhibits SARS virus

PRB Pharmaceuticals and Lee's Pharmaceuticals have announced that a recent study by Taiwan researchers from the National Health Research Institutes demonstrates TF2b and TF3, two components of v38 AMF-1, inhibit the 3C-like protease encoded by SARS-CoV. v38 AMF-1, a fraction of the flu medication VIRA 38, is best known for its ability to inhibit bird flu virus (H5N1) infections.

4 Aug 2005

Genelabs drug discovery team advances compounds against the hepatitis C virus

Genelabs Technologies today announced that a non-nucleoside compound from its internal Hepatitis C virus (HCV) drug discovery program has advanced into preclinical development.

4 Aug 2005

MDMA/Ectasy could lead to new treatments for Parkinson's disease

Researchers at Duke University have revealed new clues about Parkinson's disease which might one day lead to new treatments.

4 Aug 2005

Scientists have a plan to prevent bird flu pandemic

According to scientists the H5N1 strain of bird flu circulating in Asia which could mutate into a lethal strain and cause a pandemic, could be contained.

4 Aug 2005

Mixing slow-release painkillers with alcohol - potentially deadly

Health Canada has issued a warning that mixing some slow-release painkillers with alcohol could be potentially deadly.

4 Aug 2005

Containment of a Southeast Asian outbreak of avian influenza in humans may be possible

Though quick to caution about the many things that could go wrong, researchers say that it may be possible to contain a Southeast Asian outbreak of avian influenza in humans, buying precious time for the production of a vaccine.

3 Aug 2005

Scientist have found an unexpected effect of the interaction of PTEN and p53 genes in early stage prostate cancer

Prostate cancer, the second leading cause of cancer death for men in the United States, is caused by changes in several tummor suppressor genes including PTEN and p53. Up to 70 percent of men with prostate cancer have lost one copy of the PTEN gene at the time of diagnosis, and p53 is absent in a high number of patients with advanced prostate cancer.

3 Aug 2005

Pfizer adds warning to Celebrex arthritis drug

Pharmaceutical giant Pfizer has adapted the label of its Celebrex arthritis drug and added a prominent warning of possible cardiovascular risks, such as increased risk of heart attacks.

3 Aug 2005

Not enough women take part in heart drug trials

Scientists say because women are under-represented in the clinical trials of heart drugs, doctors are left in the dark as to how treatments may work differently in their bodies.

3 Aug 2005

First evidence that complex genetic interactions account for autism risk

Using a novel analysis of the interactions among related genes, Duke University Medical Center researchers have uncovered some of the first evidence that complex genetic interactions account for autism risk. The Duke team found that the brain mechanism that normally stops or slows nerve impulses contributes to the disease.

3 Aug 2005

Breed and placement affect skin drug delivery

Skin creams and patches might be the easiest way to give your pets medicine but their success also depends on the breed and where it’s applied.

2 Aug 2005

Drug use among Indiana youth sees biggest drop in years

A new report on alcohol, tobacco and other drug use by the Indiana Prevention Resource Center at Indiana University Bloomington demonstrates a significant downward trend in youth drug use and includes the agency's first compilation of data concerning methamphetamine use and gambling by sixth- through 12th-grade students.

2 Aug 2005

HAART reduces AIDS rates by 86%

Highly active antiretroviral therapy (HAART) for HIV-infected individuals has reduced the rate of progression to AIDS or death by 86%, according to new research from Bristol University published in The Lancet.

2 Aug 2005