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Rare Disease Day: Illumina shines a spotlight on people living with rare diseases

With a mission of empowering the rare disease community, Illumina has today partnered with medical researchers and families to highlight the importance of genomic sequencing and to shine the spotlight on the 300 million people worldwide living with a rare disease.

8 Mar 2021

Multidrug-resistant S. aureus strains may be spreading between pigs, farmworkers in North Carolina

DNA sequencing of bacteria found in pigs and humans in rural eastern North Carolina, an area with concentrated industrial-scale pig-farming, suggests that multidrug-resistant Staphylococcus aureus strains are spreading between pigs, farmworkers, their families and community residents, and represents an emerging public health threat, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

5 Mar 2021

Researchers decipher how interspecies interactions arise, evolve and are maintained

Interspecies interactions are the foundation of ecosystems, from soil to ocean to the human gut. Among the many different types of interactions, syntrophy is a particularly important and mutually beneficial interspecies interaction where one partner provides a chemical or nutrient that is consumed by the other in exchange for a reward.

5 Mar 2021

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

New research led by Thushan I. de Silva from the University of Sheffield proposes that increases in subgenomic RNA (sgRNA) expression cause increased viral transmissibility and subsequent infection. They suggest the ORF9 protein, found in high amounts of sgRNA, could be regulating interferon responses.

4 Mar 2021

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Researchers in the United States and South Africa report that the NVX-CoV2373 vaccine from Novavax has proved effective at preventing coronavirus disease (COVID-19) caused by the B.1.351 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently emerged in South Africa.

4 Mar 2021

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Researchers found a small molecule that inhibits different virus proteins and significantly reduces infection in cells. Combined with the antiviral remdesivir, its potency increases significantly, suggesting it may be a potential antiviral candidate for the treatment of COVID-19.

4 Mar 2021

Multiple COVID-19 variants of concern have reached Houston, Texas

New research by a team at Houston Methodist Hospital in the United States has modeled the aggressive genomic sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) observed in the United Kingdom to document viral community spread in Houston, Texas.

4 Mar 2021

Robotics platform could revolutionize how labs track the spread of COVID-19, other pathogens

A robotics platform designed by Toronto researchers to screen thousands of COVID-19 samples at once has the potential to revolutionize how labs track the spread of viruses and other pathogens, according to new findings.

4 Mar 2021

Evolutionary forces account for gender imbalance in the occurrence of autism, other health conditions

Evolutionary forces drive a glaring gender imbalance in the occurrence of many health conditions, including autism, a team of genetics researchers has concluded.

4 Mar 2021

SARS-CoV-2 variants do not substantially affect CD4+ and CD8+ T cell responses, study shows

Researchers from California in the United States have conducted a study showing that important adaptive immune responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not affected by four recently emerged variants of the virus.

3 Mar 2021

Researchers lay out bioinformatics bottlenecks that are hindering response to COVID-19 pandemic

A global group of researchers is calling for better integration of viral genetics, bioinformatics, and public health to enable better pandemic response now and better pandemic preparedness in the future.

3 Mar 2021

Researchers explore mutational signatures associated with exposure to microplastic pollutants

According to the World Health Organization, plastic products and their chemical derivatives present in the environment present public health concerns on a global scale and more exploration on the potential impact to human health is needed.

3 Mar 2021

Genomic surveillance can help identify how SARS-CoV-2 spreads in care homes

Care homes are at high risk of experiencing outbreaks of COVID-19, the disease caused by SARS-CoV-2. Older people and those affected by heart disease, respiratory disease and type 2 diabetes - all of which increase with age - are at greatest risk of severe disease and even death, making the care home population especially vulnerable.

3 Mar 2021

New transcriptome‐based aging clock reads the biological age of an organism

Using the model organism Caenorhabditis elegans, researchers at the University of Cologne have developed an 'aging clock' that reads the biological age of an organism directly from its gene expression, the transcriptome.

3 Mar 2021

Pharmacists discover active substances that block SARS-CoV-2 replication

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease.

3 Mar 2021

Vaccine candidate shows promise to protect against dozen-plus flu strains

Ask Eric Weaver about pandemics, and he's quick to remind you of a fact that illustrates the fleeting nature of human memory and the proximal nature of human attention: The first pandemic of the 21st century struck not in 2019, but 2009.

3 Mar 2021

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Researchers have investigated the effectiveness of a bioengineered miniprotein in protecting against SARS-CoV-2 infection in vivo. The researchers evaluated the miniprotein, LCB1, against SARS-CoV-2-mediated lung disease in human ACE2-expressing transgenic mice.

3 Mar 2021

Beckman Coulter Life Sciences Debuts Biomek NGeniuS Workstation at AGBT

Celebrating more than 85 years of innovation, Beckman Coulter Life Sciences announces its newest automated liquid handler, the Biomek NGeniuS workstation, at the virtual Advances in Genome Biology and Technology (AGBT) General Meeting.

From Beckman Coulter Life Sciences - Flow Cytometry 3 Mar 2021

COVID-19 disrupts heart muscle contraction, may lead to heart failure

Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced ability to pump blood and abnormal heart rhythms.

3 Mar 2021

Genome News and Research

Rare Disease Day: Illumina shines a spotlight on people living with rare diseases

Multidrug-resistant S. aureus strains may be spreading between pigs, farmworkers in North Carolina

Researchers decipher how interspecies interactions arise, evolve and are maintained

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Multiple COVID-19 variants of concern have reached Houston, Texas

Robotics platform could revolutionize how labs track the spread of COVID-19, other pathogens

Evolutionary forces account for gender imbalance in the occurrence of autism, other health conditions

SARS-CoV-2 variants do not substantially affect CD4+ and CD8+ T cell responses, study shows

Researchers lay out bioinformatics bottlenecks that are hindering response to COVID-19 pandemic

Researchers explore mutational signatures associated with exposure to microplastic pollutants

Genomic surveillance can help identify how SARS-CoV-2 spreads in care homes

New transcriptome‐based aging clock reads the biological age of an organism

Pharmacists discover active substances that block SARS-CoV-2 replication

Vaccine candidate shows promise to protect against dozen-plus flu strains

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Beckman Coulter Life Sciences Debuts Biomek NGeniuS Workstation at AGBT

COVID-19 disrupts heart muscle contraction, may lead to heart failure

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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