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Nanoparticles elicit neutralizing antibodies to diverse SARS-CoV-2 variants

Spike-protein-based nanoparticle vaccine candidates were retained longer in follicular dendritic cells and showed higher germinal center reactions in lymph node follicles compared to soluble spike protein vaccine.

30 Mar 2021

GlyNAC could improve many age-associated defects in older humans

A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC - a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione - could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging.

29 Mar 2021

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability.

29 Mar 2021

New recommendations for addressing disparities in cancer care

New recommendations co-developed by Dana-Farber Cancer Institute call for a significant expansion of the National Cancer Institute (NCI) and NCI-designated Comprehensive Cancer Centers to understand the causes of inequities in cancer care and a commitment to building sustained community partnerships to reduce them.

29 Mar 2021

Persistent impact on smell and taste in COVID-19 patients one year later

The presentation of the infection ranges from asymptomatic, through dry cough with fever, anosmia/dysgeusia, to shortness of breath with severe acute respiratory distress syndrome (ARDS). A new preprint research paper posted to the medRxiv* server reports on the clinical progression of anosmia and dysgeusia, in particular, one year after the infection.

29 Mar 2021

AI study on aggressive form of cancer could improve patient outcomes

International genomics research led by the University of Leicester has used artificial intelligence (AI) to study an aggressive form of cancer, which could improve patient outcomes.

26 Mar 2021

Moffitt researchers use mathematical modeling to help explain outcomes of CAR T-cell therapy

Chimeric antigen receptor T-cell therapy, or CAR T, is a relatively new type of therapy approved to treat several types of aggressive B cell leukemias and lymphomas.

25 Mar 2021

Therapeutic bed can help keep premature babies' brain oxygen levels steady during procedures

A medical device that has been shown to manage pain among babies born preterm can also help keep their brain oxygen levels steady during medical procedures, finds new analysis by researchers at UBC.

25 Mar 2021

Vaccine hesitancy could pose a major threat to public health efforts to end COVID-19

Although demand for COVID-19 vaccines currently seems high, vaccine hesitancy could pose a major threat to public health efforts to end the pandemic, according to an editorial published today in the journal Science.

25 Mar 2021

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer.

25 Mar 2021

Stop blaming Tuskegee, critics say. It’s not an ‘excuse’ for current medical racism.

For months, journalists, politicians and health officials — including New York Gov. Andrew Cuomo and Dr. Anthony Fauci — have invoked the infamous Tuskegee syphilis study to explain why Black Americans are more hesitant than white Americans to get the coronavirus vaccine.

25 Mar 2021

Researchers conduct online survey on people’s intentions regarding COVID-19 vaccination

Ahead of the first U.S. emergency use authorization for a COVID-19 vaccine, only half of Americans said they were likely to get vaccinated as soon as possible, according to an in-depth study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

25 Mar 2021

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

A new study suggests that Sargramostim, a medication often used to boost white blood cells after cancer treatments, is also effective in treating and improving memory in people with mild-to-moderate Alzheimer's disease.

24 Mar 2021

Scientists use ultrasound to map arrhythmic sites more accurately

Abnormal heart rhythms - cardiac arrhythmias - are a major worldwide health problem. Now scientists are using ultrasound for more accurate maps of arrhythmic sites in the heart for the improved success of ablation procedures.

24 Mar 2021

Online mindfulness practices may alleviate fear, anxiety and stress associated with COVID-19

The fear, anxiety and stress associated with the COVID-19 pandemic has taken a toll on mental health. But a new study suggests these symptoms may be alleviated through safe and convenient online mindfulness practices.

23 Mar 2021

Nutritional supplement may reduce risk of fatal strokes in patients with rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

23 Mar 2021

IONTAS identifies novel SARS-CoV-2 neutralising antibodies

IONTAS Limited (IONTAS) and FairJourney Biologics S.A (FJB)., leaders in the discovery and optimization of fully human antibodies, have announced the identification of neutralizing antibodies, which bind to multiple emerging SARS-CoV-2 variants.

From FairJourney Biologics 23 Mar 2021

Widening ideological gap in the U.S. may contribute to challenges in medical research

The lightning speed with which scientists developed and tested the COVID-19 vaccine is a true scientific triumph -- one that would not have been possible without the more than 70,000 volunteers who participated in clinical trials of the vaccine.

23 Mar 2021

New research could help predict acute reactions to psychedelic drugs

As psychedelics gain ground as a potential therapy for mental health disorders, there remains a pressing concern that patients in clinical trials may have adverse effects to the drugs.

22 Mar 2021

Anti-androgen drugs may help disarm coronavirus spike protein, stop progression of COVID-19

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

22 Mar 2021

Clinical Trial News and Research

Nanoparticles elicit neutralizing antibodies to diverse SARS-CoV-2 variants

GlyNAC could improve many age-associated defects in older humans

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

New recommendations for addressing disparities in cancer care

Persistent impact on smell and taste in COVID-19 patients one year later

AI study on aggressive form of cancer could improve patient outcomes

Moffitt researchers use mathematical modeling to help explain outcomes of CAR T-cell therapy

Therapeutic bed can help keep premature babies' brain oxygen levels steady during procedures

Vaccine hesitancy could pose a major threat to public health efforts to end COVID-19

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Stop blaming Tuskegee, critics say. It’s not an ‘excuse’ for current medical racism.

Researchers conduct online survey on people’s intentions regarding COVID-19 vaccination

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Scientists use ultrasound to map arrhythmic sites more accurately

Online mindfulness practices may alleviate fear, anxiety and stress associated with COVID-19

Nutritional supplement may reduce risk of fatal strokes in patients with rare genetic disorder

IONTAS identifies novel SARS-CoV-2 neutralising antibodies

Widening ideological gap in the U.S. may contribute to challenges in medical research

New research could help predict acute reactions to psychedelic drugs

Anti-androgen drugs may help disarm coronavirus spike protein, stop progression of COVID-19

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