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New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis.

1 Mar 2023

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Dementia with Lewy bodies (DLB), one of the most common forms of dementia, has no cure. Previous studies suggested that gut bacteria, the microorganisms that live in the human digestive tract, play a role in Parkinson's disease, another neurodegenerative disorder, but the bacteria involved in DLB had not been identified.

28 Feb 2023

Microglia may be the culprit behind concentration and memory problems after chemotherapy

Immune cells that keep the brain free of debris but also contribute to inflammation are the likely culprits behind the concentration and memory problems that sometimes follow one type of chemotherapy, a new study in mice suggests.

28 Feb 2023

Study reveals new mechanism in the arms race between bacteria and viruses

UT Southwestern biochemist Zhijian "James" Chen, Ph.D., famously identified the cGAS enzyme pathway that alerts the human immune system to disease-causing invaders like viruses.

28 Feb 2023

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

SARS-CoV-2 infection does not appear to influence pneumococcal colonization in the upper respiratory tract.

28 Feb 2023

An overview of the anti-inflammatory effects of nuts

Researchers summarize existing literature on the effects of consuming nuts on biomarkers of inflammation and oxidative stress.

28 Feb 2023

Maternal obesity alters the structure of placenta more than gestational diabetes mellitus

Maternal obesity alters the structure of the placenta (a vital organ that nourishes the baby during pregnancy) more than gestational diabetes mellitus (GDM; a condition is diagnosed by poor glucose control in pregnancy).

28 Feb 2023

New method to improve diagnosis of Primary Ciliary Dyskinesia in preschool age children

University of Southampton researchers have recommended a method to help diagnose preschool age children with Primary Ciliary Dyskinesia (PCD).

27 Feb 2023

Cutting just one food from the diet rather than six may help treat eosinophilic esophagitis

Eliminating animal milk alone from the diet of adults with eosinophilic esophagitis, or EoE, is as effective at treating the disease as eliminating animal milk plus five other common foods, a clinical trial funded by the National Institutes of Health has found.

27 Feb 2023

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

27 Feb 2023

Large cell therapy trial in patients with chronic heart failure shows promising results

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

27 Feb 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

More frequent cannabis use associated with higher risk of coronary artery disease

People who used marijuana daily were found to be about one-third more likely to develop coronary artery disease (CAD) compared with people who have never used the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

Head injuries may contribute to the development of glioma

Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.

24 Feb 2023

Discovery of a T cell subset points to new treatment for COPD exacerbations

Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one of the most common diagnoses for hospital admissions.

24 Feb 2023

Novel fatty liver organoid models could aid in drug discovery and testing

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.

23 Feb 2023

Skipping meals can trigger a negative effect on immune cells

Fasting may be detrimental to fighting off infection, and could lead to an increased risk of heart disease, according to a new study by the Icahn School of Medicine at Mount Sinai.

23 Feb 2023

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer's disease and to lower cholesterol.

23 Feb 2023

Long COVID more than doubles a person's risk of developing cardiovascular issues

Experiencing lasting symptoms months after catching COVID-19, also known as long COVID, was found to more than double a person's likelihood of developing cardiovascular issues, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Inflammation News and Research

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Microglia may be the culprit behind concentration and memory problems after chemotherapy

Study reveals new mechanism in the arms race between bacteria and viruses

COVID-19 does not increase the risk of Streptococcus pneumoniae infection

An overview of the anti-inflammatory effects of nuts

Maternal obesity alters the structure of placenta more than gestational diabetes mellitus

New method to improve diagnosis of Primary Ciliary Dyskinesia in preschool age children

Cutting just one food from the diet rather than six may help treat eosinophilic esophagitis

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Large cell therapy trial in patients with chronic heart failure shows promising results

Researchers explore potential new target for cancer immunotherapy

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

More frequent cannabis use associated with higher risk of coronary artery disease

Head injuries may contribute to the development of glioma

Discovery of a T cell subset points to new treatment for COPD exacerbations

Novel fatty liver organoid models could aid in drug discovery and testing

Skipping meals can trigger a negative effect on immune cells

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Long COVID more than doubles a person's risk of developing cardiovascular issues

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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