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Clinical study seeks to examine new combination therapy for treating AML patients

A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.

7 Mar 2017

Study assesses effect of combining exercise, dietary supplements on muscle mass and function

Although progressive muscle loss is a natural part of ageing, sarcopenia is generally identified when muscle mass and muscle function falls below defined thresholds.

7 Mar 2017

Nanomaterial-based bone regeneration technology could help people suffering from severe injuries

Advanced materials are revolutionizing our daily lives — from clothing to clinics to … cattle? A nanomaterial-based bone regeneration technology developed at the University of Arkansas at Little Rock helped save a valuable animal's life. In the future, this technology could help people suffering from a variety of severe injuries and ailments.

7 Mar 2017

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

Two weeks of voluntary wheel running induces higher expression of irisin--a fat-burning hormone that is released during exercise--in bone tissue in mice.

3 Mar 2017

FDA approves new nasal spray for adults who overproduce urine at night

The U.S. Food and Drug Administration today approved Noctiva (desmopressin acetate) nasal spray for adults who awaken at least two times per night to urinate due to a condition known as nocturnal polyuria (overproduction of urine during the night).

3 Mar 2017

New treatment option could provide effective therapy for patients with dermatologic conditions

Alopecia areata, atopic dermatitis and vitiligo are highly visible dermatologic conditions that can have a negative effect on patients' quality of life and overall health. An emerging treatment option, however, could provide effective therapy for patients with these conditions.

3 Mar 2017

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Ninety percent of cancer deaths are from cancer spread. Breast cancer patients, for example, typically do not die because cancer returns in their breast, they die because it spreads to other parts of their body. The most dangerous of which is the brain.

2 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Study shows how ‘secondhand sugar’ can pass from mother to infant through breast milk

Add breast milk to the list of foods and beverages that contain fructose, a sweetener linked to health issues ranging from obesity to diabetes.

2 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Chemotherapy treatment targets and kills cancer cells in the body. However, even after treatment, some cancer cells may remain in the patient's system undetected.

2 Mar 2017

Study explores consequences of poor shoe choice on health of elderly individuals

As people get older, they experience changes in their foot morphology. If they do not change their shoe size along with these transformations, older people - most of whom choose the wrong shoes - suffer, among other things, anxiety, apathy, loss of balance and falls, according to a study by the University of A Coruña.

1 Mar 2017

Commonly-prescribed drug for treating weak bone condition linked to increased risk of 'micro-cracks'

A type of drug used to treat weak bones is associated with an increased risk of 'micro-cracks' in bone, according to new research.

1 Mar 2017

Study identifies potential therapeutic target for bone repair in adults with severe injury or disease

Irish scientists are developing an advanced technology to speed up bone repair in adults who have suffered severe fractures and bone degeneration.

1 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

TUM experts decipher secrets of Achilles' heel

Walking, running, sprinting -- every movement of the foot stretches the Achilles' tendon. When jumping, the loads can approach ten times the body weight.

28 Feb 2017

Researchers justify alternative theory about cause of type 1 diabetes

An international team of researchers led by City of Hope's Bart Roep, Ph.D., the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and professor/founding chair of the Department of Diabetes Immunology, has been able to justify an alternative theory about the cause of type 1 diabetes (T1D) through experimental work.

28 Feb 2017

Fat stem cells may be preferred type for use in therapeutic applications, study shows

An international team of researchers, funded by Morris Animal Foundation, has shown that adipose (fat) stem cells might be the preferred stem cell type for use in canine therapeutic applications, including orthopedic diseases and injury.

27 Feb 2017

Fred Hutch scientists make important step in identifying specific T cells to fight against cancer

A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best suited to fight cancer.

25 Feb 2017

Bone News and Research

Clinical study seeks to examine new combination therapy for treating AML patients

Study assesses effect of combining exercise, dietary supplements on muscle mass and function

Nanomaterial-based bone regeneration technology could help people suffering from severe injuries

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

FDA approves new nasal spray for adults who overproduce urine at night

New treatment option could provide effective therapy for patients with dermatologic conditions

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

City of Hope researchers find how HER2-positive breast cancer patients develop brain metastases

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Study shows how ‘secondhand sugar’ can pass from mother to infant through breast milk

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Study explores consequences of poor shoe choice on health of elderly individuals

Commonly-prescribed drug for treating weak bone condition linked to increased risk of 'micro-cracks'

Study identifies potential therapeutic target for bone repair in adults with severe injury or disease

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

TUM experts decipher secrets of Achilles' heel

Researchers justify alternative theory about cause of type 1 diabetes

Fat stem cells may be preferred type for use in therapeutic applications, study shows

Fred Hutch scientists make important step in identifying specific T cells to fight against cancer

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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