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Rockefeller scientists describe the genetics of severe SARS-CoV-2 infection in children

One of the most terrifying aspects of the COVID pandemic has been its unpredictably severe impact on some children.

10 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Is gut microbiome lipid metabolism a determinant of human health?

Researchers highlighted the role of lipids, especially bacteria-derived lipids in the gut microbiome, in mammalian physiology in the context of immunity and metabolism. Note that commensal fungal species also produce lipid metabolites.

10 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Recently, scientists have reviewed the existing literature to elucidate the root cause of metabolic syndrome and type 2 diabetes.

10 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

Biochemist Jon Jacobs has analyzed the blood of patients with diseases and conditions such as Ebola, cancer, tuberculosis, hepatitis, diabetes, Lyme disease, brain injury and influenza.

9 Feb 2023

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found.

9 Feb 2023

Inhalable powder could protect lungs and airways from viral invasion

Researchers have developed an inhalable powder that could protect lungs and airways from viral invasion by reinforcing the body's own mucosal layer.

9 Feb 2023

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

A researchers emphasized the need to reconsider mRNA COVID-19 vaccination strategies in the future,

9 Feb 2023

A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

Study reveals how a subset of lung T regulatory cells protects against deadly pneumococcal disease

A new study by University of Liverpool researchers reveals how resistance to bacteraemic pneumonia is provided by a unique subset of lung T regulatory cells.

8 Feb 2023

Could adhering to a healthy lifestyle decrease the risk of post–COVID-19 condition?

Researchers performed a prospective cohort study among 1981 female nurses to investigate whether maintaining a healthy lifestyle decreases the risk of post–coronavirus disease 2019 (COVID-19) condition (PCC) following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

8 Feb 2023

Researchers report two unusual COVID-19-related arrhythmic cases in children

Researchers explored the association between cardiac arrhythmias in children and COVID-19 infection.

8 Feb 2023

Researchers highlight the dysregulation of hepatokines in people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is an important risk factor for type 2 diabetes and cardiovascular diseases.

7 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Inflammation News and Research

Rockefeller scientists describe the genetics of severe SARS-CoV-2 infection in children

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Is gut microbiome lipid metabolism a determinant of human health?

Casein-based diet found to protect diabetic mice against autoimmunity

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

Inhalable powder could protect lungs and airways from viral invasion

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

A microbiota-driven mechanism underlies severity of leishmaniasis infection

Study reveals how a subset of lung T regulatory cells protects against deadly pneumococcal disease

Could adhering to a healthy lifestyle decrease the risk of post–COVID-19 condition?

Researchers report two unusual COVID-19-related arrhythmic cases in children

Researchers highlight the dysregulation of hepatokines in people with NAFLD

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

Understanding the relationship between SARS-CoV-2 infection and periodontitis

Mucus-based bioactive gel could replace the clinical gold standard of autografting

The safety profile and the actual known adverse effects of COVID-19 vaccines in at-risk and healthy individuals

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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