Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

New imaging method enables rapid assessment of tumor tissue during brain surgery

Brain surgery for removing cancerous tissue is a delicate and high-stakes task. Now researchers funded by the National Institute of Biomedical Imaging and Bioengineering have created a way to improve tumor removal surgery by distinguishing cancerous tissue from healthy tissue faster.

13 Feb 2017

Study reveals new role for cancer drug in tumor immunology

A drug first designed to prevent cancer cells from multiplying has a second effect: it switches immune cells that turn down the body's attack on tumors back into the kind that amplify it. This is the finding of a study led by researchers from NYU Langone Medical Center and published recently in Cancer Immunology Research.

13 Feb 2017

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Only one new drug has become available over the past 50 years for the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus, but new research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target.

10 Feb 2017

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Researchers have identified a gatekeeper protein that prevents pancreatic cancer cells from transitioning into a particularly aggressive cell type and also found therapies capable of thwarting those cells when the gatekeeper is depleted.

9 Feb 2017

Study explores links between genetic susceptibility and heterogeneous phenotypes of lymphedema

Each year, about 1.38 million women worldwide are diagnosed with breast cancer. Advances in diagnosis and treatment have facilitated a 90-percent, five-year survival rate, among those treated.

9 Feb 2017

Loss of Golgi function may contribute to pathology of neurodegenerative diseases

Disabling a part of brain cells that acts as a tap to regulate the flow of proteins has been shown to cause neurodegeneration, a new study from The University of Manchester has found.

From The University of Manchester 9 Feb 2017

Wills Eye expert discusses what patients need to know about Age-Related Macular Degeneration

Carl D. Regillo, MD Chief of the Wills Eye Hospital Retina Service discusses what patients need to know about Age-Related Macular Degeneration.

8 Feb 2017

Study sheds light on role of brain region in social behavior and pathology in autism

Researchers at Rosalind Franklin University of Medicine and Science have induced empathy-like behavior by identifying then manipulating a brain circuit in an experimental model, an indication that new strategies may help people with autism spectrum disorder gain social abilities.

8 Feb 2017

Novel cell therapy may repair heart damage using modified cells from facial muscle

Researchers at the University of Cincinnati have received $2.4 million in federal funding to pursue research on a novel cell therapy that would repair heart damage using modified cells taken from the patient's own facial muscle.

8 Feb 2017

Researchers create first animal model of rare disease linked to problem of adrenal glands

The name of the gene is Armc5, for Armadillo repeat containing 5. Until now, its function was unknown. After 10 years of research, a team at the University of Montreal Hospital Research Centrehas succeeded in deleting this gene in experimental mice and discovered that its loss gives rise to a heretofore unidentified syndrome.

7 Feb 2017

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Scientists find new method for identifying therapeutic targets in cancers lacking tumor suppressor genes

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes.

7 Feb 2017

Neuroscientists clarify role of controversial immune system protein in Alzheimer's disease

Leading neuroscientists have clarified the role of a controversial immune system protein in Alzheimer's disease, showing it has opposing effects in early and late stages of the disease.

7 Feb 2017

New method improves speed and diagnostic efficiency during brain surgery

A new approach to the practice of surgical pathology for brain tumor patients could make for a powerful combination: more accurate, safer and more efficient operations.

7 Feb 2017

TSRI researchers uncover details behind Zika virus's unique ability to cause birth defects

The most frightening aspect of Zika virus has been its ability to produce severe fetal birth defects during pregnancy, especially microcephaly—a small head.

7 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

Scientists identify structure of androgenic receptor essential to fight against prostate cancer

A team led by researchers of the Institute of Biomedicine of the University of Barcelona and the Research Institute of the Hospital de la Santa Creu i Sant Paushows for the first time, the three-dimensional structure of the homodimeric androgen receptor ligand-binding domain, a structure that eluded researchers for years.

6 Feb 2017

WHO's new guidance aims to improve chances of survival for cancer patients

New guidance from WHO, launched ahead of World Cancer Day (4 February), aims to improve the chances of survival for people living with cancer by ensuring that health services can focus on diagnosing and treating the disease earlier.

6 Feb 2017

PENTAX Medical’s HD Stroboscopy system provides premium solution to optimize voice assessment in ENT applications

PENTAX Medical, the leading ENT endoscopic manufacturer, now offers its HD Stroboscopy system for ENT applications across Europe, Middle East and Africa. The HD Strobe system provides a premium solution to optimize voice assessment, affording six times the image detail of standard-definition video to assist in the detection of subtle pathology.

From PENTAX Medical Company 6 Feb 2017

Study provides insights into functions of astrocytes following brain injury or disease

Astrocytes have long been implicated in the pathology of a range of human neurodegenerative diseases or injuries including Alzheimer's, Huntington's Parkinson's disease, brain trauma and spinal cord injury.

3 Feb 2017

Pathology News and Research

Further Reading

New imaging method enables rapid assessment of tumor tissue during brain surgery

Study reveals new role for cancer drug in tumor immunology

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Study explores links between genetic susceptibility and heterogeneous phenotypes of lymphedema

Loss of Golgi function may contribute to pathology of neurodegenerative diseases

Wills Eye expert discusses what patients need to know about Age-Related Macular Degeneration

Study sheds light on role of brain region in social behavior and pathology in autism

Novel cell therapy may repair heart damage using modified cells from facial muscle

Researchers create first animal model of rare disease linked to problem of adrenal glands

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

Scientists find new method for identifying therapeutic targets in cancers lacking tumor suppressor genes

Neuroscientists clarify role of controversial immune system protein in Alzheimer's disease

New method improves speed and diagnostic efficiency during brain surgery

TSRI researchers uncover details behind Zika virus's unique ability to cause birth defects

PERK protein could be target for development of new drugs for progressive supranuclear palsy

Scientists identify structure of androgenic receptor essential to fight against prostate cancer

WHO's new guidance aims to improve chances of survival for cancer patients

PENTAX Medical’s HD Stroboscopy system provides premium solution to optimize voice assessment in ENT applications

Study provides insights into functions of astrocytes following brain injury or disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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