Immune System News and Research

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Delta and Delta Plus infect lung cells with higher efficiency than the original virus, research shows

The emergence of new SARS-CoV-2 variants that can spread rapidly and undermine vaccine-induced immunity threatens the end of the COVID-19 pandemic. The delta variant (B.1.617.2) emerged in India and subsequently spread globally within a short time period. Also in Germany, almost all recent infections are due to this variant.

18 Oct 2021

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

15 Oct 2021

Study: Statin treatment slightly lowers COVID-19 mortality

Statins are a recommended and common intervention for preventing cardiovascular events by reducing levels of lipoprotein cholesterol in the blood. During the pandemic, it has been debated whether statins influence the risk of death from COVID-19.

15 Oct 2021

Study reveals a detrimental role of the immune system in Lewy body dementias

T-cells respond to buildups of alpha-synuclein, the aggregated protein clumps that are a feature of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease (PD), according to a Northwestern Medicine study published in Science.

14 Oct 2021

Increased transmission in open spike conformations of SARS-CoV-2 variants

Researchers from Yale University and the University of Texas have collaborated to investigate mutations in some VOCs.

14 Oct 2021

COVID-19 booster for immunosuppressed patients with inflammatory bowel disease

Researchers have published correspondence detailing the reasoning behind providing a third booster dose to patients with inflammatory bowel disease that have been treated with drugs that can reduce the response to the COVID-19 vaccines.

14 Oct 2021

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

In a first-in-world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

13 Oct 2021

Non-invasive optical probe reveals the complex changes in tumors after immunotherapy

Johns Hopkins University engineers are the first to use a non-invasive optical probe to understand the complex changes in tumors after immunotherapy, a treatment that harnesses the immune system to fight cancer.

13 Oct 2021

COVID-19 linked to newborn complications

A recent study discusses whether pregnant women with the COVID-19 are at a higher risk for poor outcomes for themselves and their babies.

13 Oct 2021

More than half of COVID-19 survivors experience "long COVID", researchers say

More than half of the 236 million people who have been diagnosed with COVID-19 worldwide since December 2019 will experience post-COVID symptoms - more commonly known as "long COVID" - up to six months after recovering, according to Penn State College of Medicine researchers.

13 Oct 2021

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

IgA antibodies play a key role in keeping the intestinal flora in balance

The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections.

13 Oct 2021

Study finds nearly 42,000 sources of toxic "forever chemicals" that could be polluting water bodies

A new study by Environmental Working Group scientists finds almost 42,000 potential sources of the toxic "forever chemicals" known as PFAS that could be polluting surface water or drinking water in communities across the U.S.

12 Oct 2021

Researchers uncover how cancer cells use sugar residue to evade the immune system

A team of South Dakota State University chemistry researchers uncovered how cancer cells utilize a simple sugar residue to disguise themselves from the immune system. What they learned will help scientists develop more effective cancer therapeutics.

12 Oct 2021

Novel therapy approach could stop tumor growth

The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don't eat me" signal, which tells the immune cells to stand back.

12 Oct 2021

Rapid measurement of SARS-CoV-2 spike T-cells

Researchers measure SARS-CoV-2 T-cell responses in individuals vaccinated or in those who developed immunity from a prior natural infection.

12 Oct 2021

Researchers identify how estrogens can influence the growth of melanoma

The link between estrogens and breast cancer has long been defined, but a Duke-led research team has identified how these hormones can also influence the growth of other cancers, notably melanoma.

12 Oct 2021

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

A recent preprint discusses the antibody response to the nucleic acid vaccines against SARS-CoV-2 when administered to children aged 7-11 years.

12 Oct 2021

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

A new paper shows that human TLR3, TLR7, and TLR8 receptors are activated with naturally occurring RNA, but this is eliminated once modified nucleosides such as m5C, m6A, m5U s2U, or pseudouridine are incorporated.

12 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

Immune System News and Research

Delta and Delta Plus infect lung cells with higher efficiency than the original virus, research shows

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

Study: Statin treatment slightly lowers COVID-19 mortality

Study reveals a detrimental role of the immune system in Lewy body dementias

Increased transmission in open spike conformations of SARS-CoV-2 variants

COVID-19 booster for immunosuppressed patients with inflammatory bowel disease

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

Non-invasive optical probe reveals the complex changes in tumors after immunotherapy

COVID-19 linked to newborn complications

More than half of COVID-19 survivors experience "long COVID", researchers say

Anti-rheumatic drug as a potential candidate for treating COVID-19

IgA antibodies play a key role in keeping the intestinal flora in balance

Study finds nearly 42,000 sources of toxic "forever chemicals" that could be polluting water bodies

Researchers uncover how cancer cells use sugar residue to evade the immune system

Novel therapy approach could stop tumor growth

Rapid measurement of SARS-CoV-2 spike T-cells

Researchers identify how estrogens can influence the growth of melanoma

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

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