Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study supports clinical utility of DNA-based prenatal blood test in all pregnant women

A DNA-based prenatal blood test used to screen pregnancies for Down syndrome and similar chromosome abnormalities in high-risk women has moved a step closer to use in the general pregnancy population.

From Natera 3 Feb 2017

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

3 Feb 2017

Increased growth factor protects retinal blood vessels in animal models with diabetes

Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have shown that a slight increase in transforming growth factor beta (TGF-β), which is present in preclinical animal models with diabetic eye disease, protects retinal blood vessels from damage that commonly occurs in the early stages of the disease.

2 Feb 2017

Virulence of bacterial infections dependent on presence of cytotoxins, study reports

Beginning in the mid-1980s, an epidemic of severe invasive infections caused by Streptococcus pyogenes (S. pyogenes), also known as group A streptococcus (GAS), occurred in the United States, Europe, and elsewhere.

2 Feb 2017

Shape of prostate and compartments in gland differ in men with cancer, research reveals

Preliminary computerized imaging reveals the shape of the prostate and a compartment within the gland--called the transitional zone--consistently differ in men with prostate cancer than those without the disease, according to new research led by Case Western Reserve University.

1 Feb 2017

Study to investigate effectiveness of novel combination treatment for eradicating HIV

A Case Western Reserve University School of Medicine researcher has received a $2.5 million grant from Gilead Sciences, a California-based biopharmaceutical company, to see if two so-far separately-used AIDS treatments are even more effective when used as a pair.

1 Feb 2017

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment -- before symptoms of memory problems begin to surface.

31 Jan 2017

Research consortium awarded $21 million NIH grant to find ways to prevent epilepsy in patients with TBI

An international consortium of academic research institutions have been awarded a $21 million grant from the National Institutes of Health to develop better ways to prevent epilepsy in patients who have suffered traumatic brain injuries.

30 Jan 2017

Scientists decipher emergence of neuronal diversity in the cerebral cortex

The development of cerebral cortex plays a major role in the evolution of species and in particular for mankind.

30 Jan 2017

ACMG issues new Points to Consider statement on potential clinical application of genome editing

The American College of Medical Genetics and Genomics is weighing in on the genome editing/CRISPR debate with a new Points to Consider statement, "Genome Editing in Clinical Genetics."

29 Jan 2017

GUMC researchers describe lab technique to fill gaps in clinical care and research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

28 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Virginia Tech researchers find new strategy to prevent inflammatory bowel disease, colon cancer

Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein?There is an intimate link between uncontrolled inflammation in the gut associated with inflammatory bowel disease and the eventual development of colon cancer.

27 Jan 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017

Portable DNA sequencing device brought into North Hospitals to fight against anti-microbial resistance

A cutting edge, portable DNA sequencing device is being brought into North Hospitals for the first time by scientists fighting against anti-microbial resistance.

From Oxford Nanopore Technologies 25 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

Pathology News and Research

Further Reading

Study supports clinical utility of DNA-based prenatal blood test in all pregnant women

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

Increased growth factor protects retinal blood vessels in animal models with diabetes

Virulence of bacterial infections dependent on presence of cytotoxins, study reports

Shape of prostate and compartments in gland differ in men with cancer, research reveals

Study to investigate effectiveness of novel combination treatment for eradicating HIV

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

Research consortium awarded $21 million NIH grant to find ways to prevent epilepsy in patients with TBI

Scientists decipher emergence of neuronal diversity in the cerebral cortex

ACMG issues new Points to Consider statement on potential clinical application of genome editing

GUMC researchers describe lab technique to fill gaps in clinical care and research

UAB researchers find how gut fails to prevent HIV-1 infection

Virginia Tech researchers find new strategy to prevent inflammatory bowel disease, colon cancer

Researchers design antibody that recognizes and destroys blood cancer stem cells

Portable DNA sequencing device brought into North Hospitals to fight against anti-microbial resistance

Scientists discover new way to inhibit growth of glioblastoma

Tau pathology underlies deterioration of spatial cognition in Alzheimer's disease

New research exposes cellular responses linked to bird flu vaccine

‘Collateral lethality’ may create new therapeutic options for several cancers

Researchers show how adult learning is impaired in females using mouse models of Rett syndrome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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