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Clinical trial launched to analyze bovine-derived immunoglobulins for preventing COVID-19 side effects

The Hospital del Mar Medical Research Institute (IMIM), Hospital del Mar, the University of California-Davis and the University of Texas have launched a clinical trial to analyze how useful a food supplement can be for preventing the worst side effects of COVID-19.

18 Feb 2021

Clinical trial shows five-year outcomes of CAR T-cell therapy for non-Hodgkin lymphomas

A significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical trial continue to be in remission five years after receiving the chimeric antigen receptor (CAR) T cell therapy Kymriah, researchers in Penn's Abramson Cancer Center reported today in the New England Journal of Medicine.

18 Feb 2021

Sensor-based asthma inhalers can benefit pediatric asthma patients

Sensor-based inhalers integrated into health care providers' clinical workflows may help improve medication adherence and support children with asthma - and their families - to more effectively manage this condition, according to a new Northwestern and Lurie Children's study published in Pediatrics.

17 Feb 2021

$1.3 million grant funds clinical trial to test psilocybin for treating patients with phantom limb pain

The Psychedelics and Health Research Initiative at UC San Diego has received a $1.3 million grant from the Steven & Alexandra Cohen Foundation to fund a clinical trial investigating the therapeutic potential of psilocybin in treating phantom limb pain.

17 Feb 2021

Mathematical model reveals how cell turnover determines the success of adaptive therapy

One of the most challenging issues in cancer therapy is the development of drug resistance and subsequent disease progression.

17 Feb 2021

Understanding stroke and heart disease in women remains a major research priority

Understanding the sex differences in cardiovascular disease presentation and outcomes remains a major research priority demonstrated by the record number of submissions for this year's Go Red for Women® special issue of the American Heart Association's flagship journal Circulation, published online today.

17 Feb 2021

Study: Radioactive bone cement is a safer alternative for treating bone tumors

A radioactive bone cement that's injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a study led by University of California, Irvine researchers.

16 Feb 2021

Changes to gut microbiome help melanoma patients respond to immunotherapy

Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients' gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.

16 Feb 2021

New model to better predict risk of abdominal aortic aneurysms

An abdominal aortic aneurysm (AAA) can be a ticking time bomb if undiscovered in time. However, researchers at the University of Pittsburgh are developing a new model to better predict at-risk patients. And the tools they are using apply mechanical testing to the human body - which is itself a complex machine.

16 Feb 2021

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

The National Cancer Institute has granted a $2.5 million, five-year R37 MERIT Award to Dr. Bryan Burt, associate professor of surgery and chief of the Division of General Thoracic Surgery, for his research project titled, "Proteomic Determinants of Response to Checkpoint Blockade in Malignant Pleural Mesothelioma."

16 Feb 2021

Study: Targeted therapy prolongs survival in patients with advanced bladder cancer

In a new study led by researchers at Yale Cancer Center, the drug enfortumab vedotin (EV) significantly prolonged survival as compared with standard chemotherapy in patients with locally advanced or metastatic urothelial carcinoma or bladder cancer, who had previously received platinum-based treatment and a PD-1–PD-L1 inhibitor.

15 Feb 2021

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

In a new study out of University of California San Diego School of Medicine, researchers found a drug used for heart failure improves symptoms associated with postural orthostatic tachycardia syndrome, otherwise known as POTS.

15 Feb 2021

Researchers develop protocols for rapid serological surveys of SARS-CoV-2 infection

A new study by researchers from Emory and Yale Universities in the USA discusses a design for quickly launching serological surveys to assess the prevalence of this infection in a given population.

15 Feb 2021

Vaccine candidate containing tetanus toxoid potentially protective against SARS-CoV-2

Researchers from Cuba, China, and France have demonstrated the potential of coupling a viral antigen with the tetanus toxoid protein as a vaccination approach to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Feb 2021

Targeted drug combined with immunotherapy prolongs survival in patients with advanced kidney cancer

Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug, said an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

13 Feb 2021

New type of drug significantly increases survival of bladder cancer patients

A new type of drug that helps target chemotherapy directly to cancer cells has been found to significantly increase survival of patients with the most common form of bladder cancer, according to results from a phase III clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust.

13 Feb 2021

Clinical Trial News and Research

Clinical trial launched to analyze bovine-derived immunoglobulins for preventing COVID-19 side effects

Clinical trial shows five-year outcomes of CAR T-cell therapy for non-Hodgkin lymphomas

Sensor-based asthma inhalers can benefit pediatric asthma patients

$1.3 million grant funds clinical trial to test psilocybin for treating patients with phantom limb pain

Mathematical model reveals how cell turnover determines the success of adaptive therapy

Understanding stroke and heart disease in women remains a major research priority

Study: Radioactive bone cement is a safer alternative for treating bone tumors

Changes to gut microbiome help melanoma patients respond to immunotherapy

New model to better predict risk of abdominal aortic aneurysms

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

Study: Targeted therapy prolongs survival in patients with advanced bladder cancer

Existing heart failure drug may be effective in treating postural orthostatic tachycardia syndrome

Researchers develop protocols for rapid serological surveys of SARS-CoV-2 infection

Vaccine candidate containing tetanus toxoid potentially protective against SARS-CoV-2

Targeted drug combined with immunotherapy prolongs survival in patients with advanced kidney cancer

New type of drug significantly increases survival of bladder cancer patients

Star-shaped brain cells may play a key role in stuttering

Study reveals detailed map of glioblastoma in genetic, molecular detail

People previously infected with COVID-19 respond strongly to one dose of Pfizer vaccine

Echocardiographic screening for early detection of rheumatic heart disease in schools

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