Immune System News and Research

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Stem-like T cells within certain lymph nodes could be natural cancer fighters, study shows

In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters.

3 Sep 2021

Simple and rapid method measures T-cell immune response to SARS-CoV-2 virus

Researchers from Duke-NUS Medical School, together with collaborators from the National Centre for Infectious Diseases (NCID) and Singapore General Hospital (SGH), have discovered a simple and rapid method to measure the T-cell immune response to the SARS-CoV-2 virus, which causes COVID-19.

3 Sep 2021

CAR T cells expressing a natural RNA can activate the body’s own T cells against solid tumors

Chimeric antigen receptor (CAR) T cell therapy, which uses engineered T cells to treat certain types of cancers, has often been a challenging approach to treating solid tumors. CAR T cells need to recognize a specific target on cancer cells to kill them.

2 Sep 2021

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

New research has uncovered a precision medicine test using blood proteins to identify a novel patient subgroup of idiopathic multicentric Castleman disease (iMCD), a rare blood disorder, who are more likely to respond to siltuximab, the only FDA approved treatment for the disease.

2 Sep 2021

World renowned immunologist named chief of Feinberg's Division of Allergy and Immunology

Stephanie Eisenbarth, MD, PhD, has been named chief of Feinberg's Division of Allergy and Immunology in the Department of Medicine, and director of the newly formed Center for Human Immunobiology.

2 Sep 2021

Climate and COVID-19 spread

A new study examines whether the number of infections and the mortality due to the virus is related to the temperature, rainfall, sunlight, and ultraviolet index (UVI).

2 Sep 2021

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

St. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and launch a multi-faceted innate immune response to infections with live viruses and bacteria. The discovery appears today in Nature.

2 Sep 2021

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Sepsis is the leading cause of death in Brazil's intensive care units (ICUs). Among patients who progress to the severe form of the disease, 40% die, and the survivors often suffer from cardiovascular and neurological complications, as well as a significant decline in immunity lasting for years after they are discharged from hospital.

2 Sep 2021

Immune cells present in tumors from head and neck cancer patients, study reports

A new study from scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University reports that the immune cells that are the major targets of immune checkpoint inhibitors are present in tumors from head and neck cancer patients.

2 Sep 2021

Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia

A new study by researchers at Winship Cancer Institute of Emory University finds that cancer-associated mutations originate in blood progenitor cells, leading to distinct changes in both cancer and non-cancer immune cells in Waldenstrom macroglobulinemia (WM), a type of non-Hodgkin lymphoma and its precursor IgM monoclonal gammopathy of undetermined significance (MGUS).

2 Sep 2021

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine.

1 Sep 2021

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body.

1 Sep 2021

Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge

A recent US study, currently available on bioRxiv* preprint server, implies that vaccination with bacille Calmette-Guérin (BCG) can limit the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by targeting innate immune pathways and could thus be used as a platform for pinpointing early immunologic events affecting the outcome of coronavirus disease (COVID-19).

1 Sep 2021

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

More than a year after the start of the COVID-19 pandemic, several vaccines have been authorized thanks to unprecedented worldwide research efforts. These first-generation vaccines bring great hope and are a mainstay in fighting the virus.

1 Sep 2021

Innovative AI and simulation tools used to reveal the inner workings of Sar-CoV-2 virus

Argonne, industry and academia collaborate to bring innovative AI and simulation tools to the COVID-19 battlefront.

1 Sep 2021

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

After over a century of development, cancer immunotherapy (CIT) has risen to become a promising approach for treating cancer. Unlike conventional methods that try to kill cancer cells directly, CIT involves modifying or stimulating the immune system's natural ability to fight the disease. So far, various CIT treatments have shown remarkable results in terms of survival rates, and many new and combination strategies are currently under study.

1 Sep 2021

Immune System News and Research

Stem-like T cells within certain lymph nodes could be natural cancer fighters, study shows

Simple and rapid method measures T-cell immune response to SARS-CoV-2 virus

CAR T cells expressing a natural RNA can activate the body’s own T cells against solid tumors

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

World renowned immunologist named chief of Feinberg's Division of Allergy and Immunology

Climate and COVID-19 spread

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Immune cells present in tumors from head and neck cancer patients, study reports

Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

Innovative AI and simulation tools used to reveal the inner workings of Sar-CoV-2 virus

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Researchers identify biomarkers for rare, serious complication in children with COVID-19

Indoor air is an important source of exposure to harmful forever chemicals, study shows

Research highlights the importance of meninges for brain development and pathology

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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