Adipocytes News and Research

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Exploring the therapeutic potential of flavonoids in type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired glucose homeostasis.

20 Mar 2025

NKD2 protein discovery opens up new possibilities in the fight against bone loss

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Mar 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Study links intermittent fasting to slower hair growth

Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth - at least in mice.

13 Dec 2024

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.

3 Dec 2024

ARMC5 regulates saturated and unsaturated fatty acid levels in fat cells

Researchers at Osaka University identified a degradation factor for SREBP1 as essential for maintaining the balance of saturated and unsaturated fatty acids in adipose tissue.

2 Dec 2024

Research sheds light on how fat cells safely enlarge to store energy

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Professor Miguel Ángel del Pozo Barriuso, who heads the Mechanoadaptation and Caveolae Biology group at the CNIC, has identified an essential mechanism in fat cells (adipocytes) that enables them to enlarge safely to store energy.

28 Nov 2024

New discovery in the peripheral nervous system could help control obesity

An international team of researchers has discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body.

25 Nov 2024

Memories of obesity can linger in fat cells long after weight loss

Epigenetic changes from obesity persist after weight loss, altering fat cell function and increasing the risk of weight regain, impacting metabolic health.

19 Nov 2024

Adipo Therapeutics shares results of studies on potential obesity treatment

Adipo Therapeutics LLC, a late-stage, preclinical biopharmaceutical company developing a potential treatment for obesity and related metabolic disorders, presented data from two studies at the annual meeting of The Obesity Society in San Antonio.

7 Nov 2024

Microplastics accelerate aging and inflammation in fat tissue, increasing risk of chronic disease

Researchers investigate the effects of microplastic exposure on the normal aging and function of adipose tissue.

16 Oct 2024

Researchers uncover how brown fat cells increase metabolic activity

Special fat cells known as brown adipocytes help maintaining body temperature by converting calory-rich nutrients into heat.

16 Sep 2024

High linoleic acid intake during pregnancy may harm fetal growth and raise obesity risk

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and inflammation in offspring. However, more research is needed to fully understand these effects in humans.

10 Sep 2024

Review explores WNT5B and WNT10B roles in osteosarcoma

A new review was published in Oncotarget's Volume 15 on August 2, 2024, entitled, "Targeting WNT5B and WNT10B in osteosarcoma."

4 Sep 2024

Tirzepatide beats semaglutide in lowering diabetes risk and cardiovascular events in obesity patients

A study published in eClinicalMedicine found that tirzepatide outperforms semaglutide in reducing the risk of type 2 diabetes and major cardiovascular events among individuals with obesity, with or without existing diabetes, while also achieving greater weight loss.

28 Aug 2024