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First FDA-approved islet transplant at UI Health ends insulin dependence

Doctors at UI Health performed the first islet transplant with Lantidra, the only therapy approved by the U.S. Food and Drug Administration to treat brittle type 1 diabetes.

4 Sep 2025

Faster progression to severe diabetes observed in people with learning disabilities

People with learning disabilities progress faster to severe type 2 diabetes and are at greater risk of dying from their condition than people without these disabilities, suggests research published in the open access journal BMJ Open Diabetes Research & Control.

2 Sep 2025

Drug-coated devices not associated with improved outcomes in patients with peripheral artery disease

Drug-coated stents and balloons were not associated with reduced risk of amputation or improved quality of life compared with uncoated devices in two trials in peripheral artery disease (PAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Study shows brain keeps internal body map intact after amputation

Researchers tracked brain activity before and after arm amputation and found that hand and lip maps in the cortex remained remarkably stable for up to five years. This challenges decades-old assumptions of large-scale remapping and supports the idea of a resilient internal body model.

24 Aug 2025

Study shows the brain’s body map remains stable after limb loss

New research from the University of Pittsburgh School of Medicine and Cambridge University upends a long-standing belief about brain plasticity.

21 Aug 2025

Toe transfer surgery outperforms replantation in hand function recovery

For patients with amputations affecting the hand, toe transfer surgery provides an alternative to replanting the amputated digits and may lead to greater improvement in hand function and other key outcomes, reports a study in the August issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

7 Aug 2025

Apple snail eye regeneration offers new insights into human sight restoration

The eye of the apple snail is unusually similar to a human eye-but, unlike human eyes, it can regrow itself if injured or even amputated.

6 Aug 2025

Hispanic people more likely to develop peripheral neuropathy than white adults

Hispanic people have an increased risk of peripheral neuropathy compared to white people that cannot be explained by many health, lifestyle and social risk factors, according to a study published July 16, 2025, in Neurology, the medical journal of the American Academy of Neurology.

16 Jul 2025

Heart healthy habits boost overall body health and longevity

People who had more heart-healthy habits and factors, as assessed by the American Heart Association's Life's Simple 7 metrics for ideal cardiovascular health, had more positive benefits for whole body health, according to a review of research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

16 Jul 2025

Improving early detection of peripheral artery disease with a new diagnostic method

An alternative diagnostic method could improve early detection and treatment of peripheral artery disease (PAD), according to a new study from the University of Surrey.

10 Jul 2025

AI reveals hidden bias behind higher amputation rates in minority and rural patients

Why do rural adults and racial and ethnic minorities with vascular disease get major leg amputations more often? A new study out today in Epidemiology uses AI to solve the mystery, finding an unaccounted-for factor that researchers think points to implicit bias in the clinical decision-making process.

10 Jul 2025

New guidance aims to improve blood clot prevention in chronic limb-threatening ischemia patients

A new statement from leading heart and blood vessel experts in Europe is providing clinical guidance for treatments to prevent blood clots in patients with a serious condition called chronic limb-threatening ischaemia (CLTI), after they have had procedures to restore blood flow in their lower limbs.

19 Jun 2025

What matters more for diabetes risk: lifestyle or body weight?

A large, multi-ethnic US cohort study found that combining healthy lifestyle factors—non-smoking, regular physical activity, a healthy diet, and moderate alcohol consumption into a Lifestyle Risk Factor Index (LSRI) was linked to a significantly lower risk of type 2 diabetes. However, BMI was a stronger predictor of diabetes risk, and the impact of lifestyle varied across ethnic groups.

18 Jun 2025

Peripheral arterial disease leads to more leg amputations in deprived communities

Leg amputation rates caused by arterial disease are four times as high in the most disadvantaged areas in England.

12 Jun 2025

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025

Study could change the definition of wound closure in diabetes care

In patients with diabetic foot ulcers that looked healed and met the current definition of a closed wound, closed ulcers with functionally defective skin that lost more body water were likely to re-open, according to a new National Institutes of Health (NIH) Diabetic Foot Consortium study, led by researchers at the University of Pittsburgh and published today in Diabetes Care.

31 May 2025

New test can measure performance for lower-limb amputees using bone-anchored prostheses

A test developed at the University of Colorado Anschutz Medical Campus that measures both prosthetic donning time and mobility in lower-limb amputation, shows that a prosthesis anchored to bone goes on faster than a traditional socket-style prosthesis.

23 May 2025

Palliative care for cardiovascular conditions may help relieve symptoms and improve quality of life

Palliative care may help relieve symptoms and improve quality of life for people with cardiovascular disease and ensure that treatment is aligned with the patient's personal beliefs and values throughout all stages of illness, whether they are hospitalized in a cardiac intensive care unit or receiving outpatient care, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

15 May 2025

The Surgeon-Scientist Pioneering Regenerative Engineering

In this interview, Sir Prof. Cato T. Laurencin, the 2025 Coulter Lecturer, discusses how he is addressing today’s medical challenges using the technology of the future.

From Pittcon 5 May 2025

Study finds high rates of undiagnosed and untreated peripheral artery disease

A new Intermountain Health study finds that peripheral artery disease, a condition that affects more than 10 million Americans over the age of 40, is often underdiagnosed and undertreated, with fewer women getting guideline-directed medical therapy than men.

31 Mar 2025