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New genetic risk test estimates inherited risk for cardiovascular conditions

Researchers at Mass General Brigham Heart and Vascular Institute and collaborators have developed and validated a new genetic risk test that can estimate a person's inherited risk for eight common cardiovascular conditions, offering a more comprehensive approach to prevention.

29 Apr 2026

AI tool estimates biological age from photos to predict cancer outcomes

The Mass General Brigham research team behind FaceAge, an artificial intelligence (AI) tool that can estimate a person's biological age from a single photo, is reporting in a new study that estimating biological age from multiple photos taken over time can provide even more information about how well a person with cancer will do with treatment.

28 Apr 2026

Noninvasive brain monitoring reveals hidden oxygen deprivation in ICU patients

In neurological intensive care, it is quickly learned that the brain cannot wait. As the most sensitive organ in the human body, it can sustain irreversible damage after just a few minutes of severe hypoxia.

27 Apr 2026

Apixaban reduces complications, helps older adults spend more time at home after blood clots

Older adults recovering from serious blood clots often face long periods of hospitalization or rehabilitation due to a higher rate of recurrence.

27 Apr 2026

Study reveals high use of complementary health approaches in seniors

Researchers say the finding highlights the need for more evidence and better conversations about risks and benefits of mindfulness, yoga, tai chi, acupuncture, and other complementary health approaches.

25 Apr 2026

New gene therapy improves hearing in patients with rare genetic deafness

A new international study co-led by investigators from Mass General Brigham and the Eye & ENT Hospital of Fudan University shows that a gene therapy for a rare form of genetic deafness successfully restored hearing in most participants, with results lasting up to 2.5 years.

23 Apr 2026

Study finds no benefit of stronger antibiotics for sinusitis

Acute sinusitis leads to more antibiotic prescriptions for U.S. adults than any other condition, but there is no consensus on which antibiotic is preferred for uncomplicated cases.

20 Apr 2026

Generative AI falls short in diagnostic reasoning despite accuracy

Despite increasing use of artificial intelligence (AI) in health care, a new study led by Mass General Brigham researchers from the MESH Incubator shows that generative AI models continue to fall short at their clinical reasoning capabilities.

13 Apr 2026

Mezagitamab shows promise in treating immune thrombocytopenia patients

Results from a phase 2 clinical trial designed and overseen by researchers at Mass General Brigham Cancer Institute show that the investigational medication mezagitamab can effectively boost platelet counts in patients with immune thrombocytopenia (ITP), an autoimmune disease characterized by elevated platelet destruction and reduced platelet production that increases bleeding risk and compromises quality of life.

11 Apr 2026

Long-term excess weight is a stronger predictor of cardiovascular risk

Obesity is a known risk factor for cardiovascular disease, but people's weights can shift over time, and little is known about the cumulative impact of excess weight.

8 Apr 2026

Smartphone app HabitWorks improves anxiety and depression symptoms

In an effort to increase access to evidence-based interventions to help manage anxiety and depression, Mass General Brigham investigators have developed and tested a novel digital intervention called HabitWorks.

2 Apr 2026

Targeted therapy pralsetinib improves outcomes in RET fusion-positive NSCLCs

In some non-small cell lung cancers (NSCLCs), changes to the RET gene (known as RET fusions) can drive tumor growth.

1 Apr 2026

AI scribes modestly reduce clinician documentation time and EHR use

Documenting a patient visit in the electronic health record (EHR) is essential to healthcare delivery, but also a major contributor to clinician burnout.

1 Apr 2026

Trump’s one big beautiful bill act darkens outlook for government-backed clinics

Bluestem Health, a clinic that serves low-income and uninsured patients in Lincoln, Nebraska, has lost money for the last two years.

1 Apr 2026

Red blood cell exchange transfusion may provide benefits for patients with severe babesiosis

A new study led by investigators from Mass General Brigham and Yale School of Public Health reveals that red blood cell exchange transfusion (ET) may provide critical benefits for patients hospitalized with severe babesiosis.

30 Mar 2026

Intensive cholesterol‑lowering therapy reduces first major cardiac event in high‑risk patients with diabetes

Mass General Brigham researchers found that the intensive cholesterol‑lowering therapy evolocumab reduced the risk of a first major cardiovascular event in high‑risk patients who did not have known atherosclerosis (the build-up of plaque inside artery walls) but did have diabetes.

28 Mar 2026