Immunodeficiency News and Research

RSS

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Plant-based diets could curb climate change and infectious diseases, experts say

A new review in Open Forum Infectious Diseases links animal agriculture to climate change, antimicrobial resistance, and infectious disease spread. The authors urge healthcare providers to promote plant-based diets as a practical step to protect planetary and public health.

28 Oct 2025

Newly discovered perineural pathway enables HIV virus to redistribute throughout the body

Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, researchers have now identified a perineural pathway through which the HIV virus can redistribute throughout the body.

28 Oct 2025

Experimental gene therapy restores immune system function in children with genetic immune disorder

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.

15 Oct 2025

Gene therapy shows long-term success in children with rare immune disorder

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the long-term safety and efficacy of the curative treatment, in a study led by a UCL researcher.

15 Oct 2025

Researchers develop AI system to decode the human immune system

Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved.

9 Oct 2025

Newborn genomic screening may detect hundreds of additional childhood conditions

Adding genomic sequencing to newborn blood screening would detect hundreds of additional childhood conditions, providing much earlier diagnosis and treatment, according to a new study. A baby's genome, which stays with them for life, could also be re-examined if a health issue arises during their lifetime.

9 Oct 2025

New survey reveals Americans' perception of the growing need for plasma-derived medicines

International Plasma Awareness Week (IPAW) takes place globally from October 6-10. The week encourages communities around the world to recognize the vital role of plasma in creating lifesaving medicines and honors those who donate.

6 Oct 2025

New guidelines improve care for respiratory infections in leukemia patients

People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections.

28 Aug 2025

Investigation raises concerns over tooth stem cell banking claims

Parents are spending thousands of pounds to bank stem cells from their children's milk teeth – but the recipient companies' claims about their future medical value are unproven and potentially misleading, reveals an investigation by The BMJ, published today.

21 Aug 2025

HIV trial points to semaglutide as a new anti-aging contender

Once-weekly semaglutide significantly slowed epigenetic aging in adults with HIV-associated lipohypertrophy, as measured by multiple DNA methylation clocks in a randomized controlled trial. These exploratory findings suggest GLP-1 receptor agonists could impact biological aging but require further validation in broader populations.

4 Aug 2025

Virtual memory T cells provide nonspecific immunity for infants early in life

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.

31 Jul 2025

Single injection of gene therapy at birth may offer lasting protection against HIV

A new study in Nature shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.

30 Jul 2025

Researchers classify how specific genetic mutations correspond to rare disorders

The NF-κB signaling pathway plays a pivotal role in how our bodies fight infection, heal, and regulate inflammation. At the heart of this pathway is the NEMO protein, encoded by the IKBKG gene.

30 Jul 2025

Louisiana upholds its HIV exposure law as other states change or repeal theirs

When Robert Smith met his future girlfriend in 2010, he wanted to take things slowly. For Smith, no relationship had been easy in the years since he was diagnosed with the human immunodeficiency virus, or HIV.

21 Jul 2025

Eating habits directly influence vaginal microbiome, research finds

A cross-sectional study of young Italian women found that higher intake of animal protein and alcohol is associated with vaginal microbiota dysbiosis, while linolenic acid (a plant-based omega-3) and dietary fiber support beneficial Lactobacillus communities.

7 Jul 2025

Twice-yearly injection could transform HIV prevention efforts

Preventative therapies for HIV-1 (Human Immunodeficiency Virus type 1) have made leaps and bounds over the past decade. A once-daily pill named PrEP, or pre-exposure prophylaxis, has been a stalwart for HIV prevention-but only if people take it consistently and can routinely access a pharmacy.

3 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Study explores how a familiar spice tackles the toughest cancer cells

Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress colorectal cancer stem-like cells, especially in early adenomas. Curcumin shifts these cells toward differentiation, delays tumor growth in mice, and may offer a safe preventive strategy.

27 Jun 2025

Study: HIV is a flexible cellular hijacker

University of Michigan researchers have uncovered new details of the process that HIV uses to hijack cells’ transportation systems for its own survival.

19 Jun 2025

New electrochemical device advances point-of-care HIV diagnostics

Accurate monitoring of CD4+ T cell counts is vital for evaluating immune health and guiding treatment in people living with Human Immunodeficiency Virus (HIV).

30 May 2025