Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Spatial intelligence platform supports health policy decisions aimed at ending HIV

INCLIVA Healthcare Research Institute-University Clinical Hospital of Valencia, the Universitat Politècnica de València - through its VRAIN Institute, the Valencia Anti-AIDS Committee and the Centre for Epidemiological Studies on Sexually Transmitted Infections and AIDS in Catalonia (CEEISCAT) have joined forces to develop a spatial intelligence platform to support health policy decisions aimed at optimizing the prevention of human immunodeficiency virus (HIV) and accelerating its early diagnosis.

5 Mar 2026

New HIV-seq tool advances understanding of persistent viral reservoirs

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission.

3 Mar 2026

Obesity sharply increases hospitalisation risk from infections, global analysis shows

Adult obesity is associated with a substantially higher risk of severe hospital-treated or fatal infections across multiple pathogens, with risk increasing as obesity severity rises. Global modelling suggests roughly one in ten infection-related deaths worldwide may be attributable to adult obesity, although causality cannot be confirmed.

15 Feb 2026

A pill that confirms you actually swallowed your medicine

SAFARI capsule technology offers a novel solution for medication adherence, using a dissolvable Faraday cage to verify ingestion without batteries or waste.

12 Jan 2026

New federal guidelines shift cervical cancer screening to HPV testing

New cervical cancer screening guidelines emphasize self-collection and hrHPV testing, aiming to increase screening rates and improve women's health outcomes.

8 Jan 2026

To knock down health-system hurdles between you and HIV prevention, try these 6 things

A couple of years ago, Matthew Hurley got the kind of text people fear.

5 Jan 2026

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

New AI investment aims to accelerate the search for an effective HIV vaccine

As of 2024, over 40 million people in the world are diagnosed with human immunodeficiency virus (HIV)-a chronic, life-threatening infection that remains one of the leading global causes of death.

18 Nov 2025

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Fondazione Telethon announces the positive opinion issued by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending marketing authorization in the European Union for Waskyra, an ex vivo gene therapy for Wiskott-Aldrich Syndrome (WAS), a rare and life-threatening primary immunodeficiency.

14 Nov 2025

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients through a collaboration with Boston Children's Hospital.

7 Nov 2025

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025

Plant-based diets could curb climate change and infectious diseases, experts say

A new review in Open Forum Infectious Diseases links animal agriculture to climate change, antimicrobial resistance, and infectious disease spread. The authors urge healthcare providers to promote plant-based diets as a practical step to protect planetary and public health.

28 Oct 2025

Newly discovered perineural pathway enables HIV virus to redistribute throughout the body

Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, researchers have now identified a perineural pathway through which the HIV virus can redistribute throughout the body.

28 Oct 2025

Experimental gene therapy restores immune system function in children with genetic immune disorder

An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.

15 Oct 2025

Gene therapy shows long-term success in children with rare immune disorder

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the long-term safety and efficacy of the curative treatment, in a study led by a UCL researcher.

15 Oct 2025

Researchers develop AI system to decode the human immune system

Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved.

9 Oct 2025

Newborn genomic screening may detect hundreds of additional childhood conditions

Adding genomic sequencing to newborn blood screening would detect hundreds of additional childhood conditions, providing much earlier diagnosis and treatment, according to a new study. A baby's genome, which stays with them for life, could also be re-examined if a health issue arises during their lifetime.

9 Oct 2025

New survey reveals Americans' perception of the growing need for plasma-derived medicines

International Plasma Awareness Week (IPAW) takes place globally from October 6-10. The week encourages communities around the world to recognize the vital role of plasma in creating lifesaving medicines and honors those who donate.

6 Oct 2025

New guidelines improve care for respiratory infections in leukemia patients

People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections.

28 Aug 2025