Induced Pluripotent Stem Cells News and Research

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Review: Pathogenesis, diagnosis, and management of harlequin ichthyosis

Harlequin ichthyosis (HI) is a rare, severe genetic skin disorder caused by ABCA12 mutations, leading to defective lipid transport and loss of skin barrier function.

17 Feb 2026

Senescent astrocytes identified as key drivers of Alzheimer's progression

Researchers from the NeuroAD group (Neuropathology of Alzheimer's Disease) within the Department of Cell Biology, Genetics and Physiology at the University of Málaga, also affiliated with IBIMA-BIONAND Platform and CIBERNED, have made a pioneering breakthrough in the fight against this disease by identifying astrocytes as a promising cellular target for the development of future therapies.

16 Feb 2026

Northwestern scientists develop advanced organoid model for human spinal cord injury

Northwestern University scientists have developed the most advanced organoid model for human spinal cord injury to date.

11 Feb 2026

Chronic brain compression triggers neuron death through multiple pathways

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord.

9 Feb 2026

Stem cell implants aim to restore dopamine in Parkinson’s disease

Parkinson's disease is a progressive neurodegenerative disorder that affects more than one million people in the United States, with approximately 90,000 new cases diagnosed each year.

5 Feb 2026

Advancing brain microphysiological systems for in vitro neurotoxicity and cognitive function testing

Brain microphysiological systems are reshaping in vitro neurotoxicity testing through functional validation and advanced disease modeling.

From Yokogawa Life Science 3 Feb 2026

Gene therapy targeting connexin 43 shows promise across inherited heart diseases

University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse model can dramatically improve heart function and extend survival in several inherited forms of arrhythmogenic cardiomyopathy (ACM)

26 Jan 2026

Alterations in liver metabolism experienced by individuals with Down syndrome

Researchers at the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) have uncovered compelling evidence that individuals with Down syndrome experience significant alterations in liver metabolism, including elevated levels of bile acids in the bloodstream and other biomarkers of liver dysfunction.

22 Jan 2026

UC San Diego project aims to bioprint patient-specific transplantable human livers

Liver failure is one of the most serious and deadly medical conditions, claiming thousands of lives each year as patients in the United States wait for a donor organ.

14 Jan 2026

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors.

8 Jan 2026

First human 'lung-on-chip' model developed using stem cells from a single donor

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

Combining stem cell therapy and BDNF enhancement to manage Parkinson’s disease

Parkinson's disease (PD) is an age-related, progressive, neurodegenerative condition, caused by loss of dopamine-producing neurons.

16 Dec 2025

Study reveals how Ebola and Marburg viruses damage the human gut

Ebola (EBOV) and Marburg virus (MARV) are highly lethal viruses that cause severe disease in infected patients by extensively damaging the body.

11 Dec 2025

UCI MIND secures major funding for new Alzheimer's research facility

With a $50 million lead gift from the Quilter family and approximately $30 million in new commitments, the University of California, Irvine's Institute for Memory Impairments and Neurological Disorders will begin planning to build a state-of-the-art research and care facility to enhance its position as a global leader in Alzheimer's disease and related dementias research and patient care.

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

Induced Pluripotent Stem Cells News and Research

Review: Pathogenesis, diagnosis, and management of harlequin ichthyosis

Senescent astrocytes identified as key drivers of Alzheimer's progression

Northwestern scientists develop advanced organoid model for human spinal cord injury

Chronic brain compression triggers neuron death through multiple pathways

Stem cell implants aim to restore dopamine in Parkinson’s disease

Advancing brain microphysiological systems for in vitro neurotoxicity and cognitive function testing

Gene therapy targeting connexin 43 shows promise across inherited heart diseases

Alterations in liver metabolism experienced by individuals with Down syndrome

UC San Diego project aims to bioprint patient-specific transplantable human livers

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

First human 'lung-on-chip' model developed using stem cells from a single donor

Combining stem cell therapy and BDNF enhancement to manage Parkinson’s disease

Study reveals how Ebola and Marburg viruses damage the human gut

UCI MIND secures major funding for new Alzheimer's research facility

JAX wins $30 million contract to create computational "digital twins" of the human heart

Automated production of lung organoids could revolutionize the development of treatments

Regenerative medicine offers a pathway toward curing type 1 diabetes

Immune system abnormalities identified as core mechanism in major depressive disorder

Breakthrough medium transforms canine stem cells into beating cardiomyocytes

UCI Health launches clinical trial to test investigational cell therapy for lupus

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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