Induced Pluripotent Stem Cells News and Research

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Alterations in liver metabolism experienced by individuals with Down syndrome

Researchers at the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) have uncovered compelling evidence that individuals with Down syndrome experience significant alterations in liver metabolism, including elevated levels of bile acids in the bloodstream and other biomarkers of liver dysfunction.

22 Jan 2026

UC San Diego project aims to bioprint patient-specific transplantable human livers

Liver failure is one of the most serious and deadly medical conditions, claiming thousands of lives each year as patients in the United States wait for a donor organ.

14 Jan 2026

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors.

8 Jan 2026

First human 'lung-on-chip' model developed using stem cells from a single donor

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

Combining stem cell therapy and BDNF enhancement to manage Parkinson’s disease

Parkinson's disease (PD) is an age-related, progressive, neurodegenerative condition, caused by loss of dopamine-producing neurons.

16 Dec 2025

Study reveals how Ebola and Marburg viruses damage the human gut

Ebola (EBOV) and Marburg virus (MARV) are highly lethal viruses that cause severe disease in infected patients by extensively damaging the body.

11 Dec 2025

UCI MIND secures major funding for new Alzheimer's research facility

With a $50 million lead gift from the Quilter family and approximately $30 million in new commitments, the University of California, Irvine's Institute for Memory Impairments and Neurological Disorders will begin planning to build a state-of-the-art research and care facility to enhance its position as a global leader in Alzheimer's disease and related dementias research and patient care.

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

Automated production of lung organoids could revolutionize the development of treatments

A team of scientists have developed a simple method for automated manufacturing of lung organoids which could revolutionize the development of treatments for lung disease.

1 Dec 2025

Regenerative medicine offers a pathway toward curing type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

26 Nov 2025

Immune system abnormalities identified as core mechanism in major depressive disorder

Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea.

21 Nov 2025

Breakthrough medium transforms canine stem cells into beating cardiomyocytes

In research, induced pluripotent stem (iPS) cells are derived from skin, urine, or blood samples and developed into other cells, like heart tissue, that researchers want to study.

21 Nov 2025

UCI Health launches clinical trial to test investigational cell therapy for lupus

UCI Health has opened a clinical trial to test an investigational cell therapy for lupus with the potential to give patients long-term remission of symptoms.

17 Nov 2025

Scientists invent new method for manufacturing platelet-producing cells from stem cells

Platelets are small, disc-shaped cell fragments in the blood that are essential to stop bleeding and to initiate blood clotting after injury.

13 Nov 2025

SwRI-developed single-use 3D-printed bioreactor harvests induced Pluripotent Stem Cells

Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases.

12 Nov 2025

Mayo Clinic scientists create stem cell patch to heal hearts without surgery

Mayo Clinic researchers have developed a pioneering method to mend damaged hearts without open-heart surgery, an advance that could one day transform the treatment of heart failure.

5 Nov 2025

Flexible drug-delivery patch can promote tissue healing after a heart attack

MIT engineers have developed a flexible drug-delivery patch that can be placed on the heart after a heart attack to help promote healing and regeneration of cardiac tissue.

4 Nov 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

New method yields up to twice as many therapeutic myogenic cells as previous protocols

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

30 Oct 2025

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

A recent review published in Engineering explores the construction and potential applications of spinal cord and peripheral nerve organoids for regenerative medicine in neurotrauma.

24 Oct 2025