Lentivirus News and Research

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Lentivirus is a genus of slow viruses of the Retroviridae family, characterized by a long incubation period.

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

Celebrating the Alderley Park Grand Opening

HQ Plasmid Center of Excellence based at UK life science hotspot now open for business.

From Charles Rivers Laboratories Cell and Gene Therapy 24 Oct 2022

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

A pseudovirus system based on deep mutational scanning determines how SARS-CoV-2 mutations can affect its ability to escape neutralization.

18 Oct 2022

Astrea Bioseparations introduces Nereus LentiHERO, a fit-for-purpose solution for lentiviral vector purification

Astrea Bioseparations (“Astrea Bio”), a leading provider of novel purification and separation tools supporting the development of next-generation therapeutics, has announced today the commercial launch of its Nereus LentiHERO™ lentiviral vector (LVV) purification technology.

29 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

In a recent study published in the journal eBioMedicine, researchers in Denmark and Sweden administered a cationic liposome-adjuvanted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit vaccine as a subcutaneous (s.c.) prime-intranasal (i.n.) boost strategy to elicit mucosal immune responses among SARS-CoV-2-infected Syrian hamsters.

14 Sep 2022

The neutralizing antibody escape of BA.2.75 in mRNA-vaccinated and BA.1-infected individuals

Investigators analyzed the neutralization escape of the SARS-CoV-2 Omicron BA.2.75 variant.

17 Aug 2022

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

In a new study, researchers developed nanocomposite coatings to prevent surface contamination by a human coronavirus (HCoV).

4 Aug 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

The neutralizing antibody response in mRNA vaccinated and boosted healthcare workers against major circulating SARS-CoV-2 Omicron subvariants

Researchers assessed the duration of the neutralizing antibody responses after SARS-CoV-2 mRNA booster vaccination.

27 Jul 2022

Lentivirus News and Research

Further Reading

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

MIT researchers develop new technique for genome-wide studies of the liver

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

Celebrating the Alderley Park Grand Opening

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

Astrea Bioseparations introduces Nereus LentiHERO, a fit-for-purpose solution for lentiviral vector purification

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

The neutralizing antibody escape of BA.2.75 in mRNA-vaccinated and BA.1-infected individuals

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

The neutralizing antibody response in mRNA vaccinated and boosted healthcare workers against major circulating SARS-CoV-2 Omicron subvariants

Why Omicron is more infectious than other SARS-CoV-2 variants

Safety and immunogenicity of Moderna vaccines containing mRNA encoding the spike protein of different SARS-CoV-2 strains

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

L452R mutation a key player in the evolution of SARS-CoV-2

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Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics