Triple Negative Breast Cancer News and Research

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OneTouch-PAT system detects breast cancer in under a minute without compression

A breast scan for detecting cancer takes less than a minute using an experimental system that combines photoacoustic and ultrasound imaging, according to a study in IEEE Transactions on Medical Imaging.

12 Jul 2025

ALKBH3 regulates glycolysis and doxorubicin resistance in triple negative breast cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how ALKBH3-regulated m1A of ALDOA potentiates glycolysis and doxorubicin resistance of triple negative breast cancer cells.

12 Jul 2025

High-intensity focused ultrasound induces ferroptosis for tumor immune activation

This new article publication from Acta Pharmaceutica Sinica B, discusses high intensity forced ultrasound-driven ferroptosis as a strategy for anti-tumor immune priming.

12 Jul 2025

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer

A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms."

10 Jul 2025

Evolutionary mutation weakens human immune response to solid tumors

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to non-human primates.

3 Jul 2025

Rarely studied RNA linked to triple-negative breast cancer

Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable.

1 Jul 2025

Targeting mitochondrial dynamics to combat breast cancer metastasis

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and limited therapeutic targets.

27 Jun 2025

New AI tool characterizes the diversity of individual cells within tumors

A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI tool to better characterize the diversity of individual cells within tumors, opening doors for more targeted therapies for patients.

24 Jun 2025

Researchers identify cellular hotspots that trigger ferroptosis

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered how a unique interaction between two cellular compartments, namely the endoplasmic reticulum (ER) and mitochondria, can act as a central ignition point for ferroptosis, a form of cell death driven by lipid oxidation and iron.

14 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

Myeloid cells shape tumor microenvironments and influence cancer progression

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments (TME), influencing tumor progression, immune evasion, and therapeutic resistance.

3 Jun 2025

Redlining continues to impact breast cancer survival in America

In neighborhoods across America, women face a daunting threat from a federal practice that, although it was outlawed decades ago, continues to negatively impact their health today.

10 May 2025

Breast cancer deaths decline in young women across all racial and subtype groups

From 2010 to 2020, breast cancer deaths among women ages 20-49 declined significantly across all breast cancer subtypes and racial/ethnic groups, with marked declines starting after 2016, according to an analysis of data from the Surveillance, Epidemiology, and End Results (SEER) registry presented at the American Association for Cancer Research (AACR) Annual Meeting 2025, held April 25-30.

29 Apr 2025

Surgery may not be necessary for some early-stage breast cancer patients

Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant (pre-surgical) chemotherapy and standard radiation treatment, according to new data from researchers at The University of Texas MD Anderson Cancer Center.

24 Apr 2025

Lipid metabolism as a driver of therapy resistance in triple negative breast cancer

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).

20 Apr 2025

High-fat diet linked to increased breast cancer metastasis risk

Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs – metastasize –. But the causes of this association are still not well understood.

2 Apr 2025

Study links linoleic acid to triple-negative breast cancer growth

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat "triple negative" breast cancer subtype, according to a preclinical study led by Weill Cornell Medicine investigators.

1 Apr 2025