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Metformin targets the gut instead of the liver to lower glucose

For decades, physicians and scientists thought metformin, the leading Type 2 diabetes medication taken by millions worldwide, mainly targets the liver to suppress glucose production.

8 May 2026

Building large DNA pieces to create custom microbes

A review in Quantitative Biology demonstrates that scientists can now reliably build and combine very large pieces of DNA, making it much easier to redesign microbes such as yeast and bacteria to act as efficient "cell factories."

7 May 2026

Cryo-electron microscopy offers an unprecedented view of gene transcription

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life.

30 Apr 2026

Silencing a cellular stress signal could extend human lifespan

Silencing a major cellular stress signal could be the key to a longer life, according to new University of Sheffield research.

30 Apr 2026

Detailed images reveal DNA repair mechanism in cancer-related proteins

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

28 Apr 2026

Bioengineered chewing gum reduces cancer-linked oral microbes

Researchers led by Henry Daniell of the School of Dental Medicine have shown that extracts from bioengineered chewing gum reduce the levels of three microbes known to be associated with head and neck squamous cell cancer (HNSCC), paving the way for more effective and affordable therapies.

23 Apr 2026

Epigenome proteins shape dynamic gene expression beyond simple on-off

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off.

21 Apr 2026

Study finds no benefit of stronger antibiotics for sinusitis

Acute sinusitis leads to more antibiotic prescriptions for U.S. adults than any other condition, but there is no consensus on which antibiotic is preferred for uncomplicated cases.

20 Apr 2026

Yeast model reveals mechanisms behind premature aging from progerin

A new research paper was published in Volume 18 of Aging-US on April 3, 2026, titled "Modeling premature aging in yeast via the expression of Progerin."

17 Apr 2026

Study explains failure of cellular cleanup in neurodegenerative diseases

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled.

15 Apr 2026

CFHR1 could be a new diagnostic marker for IgA nephropathy

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced extracellular matrix production, and variable infiltration of inflammatory cells.

30 Mar 2026

Do multi-strain probiotics improve long covid symptoms?

Multi-strain probiotics show potential to modulate gut microbiome in long COVID, yet their impact on inflammation and recovery is not statistically significant.

27 Mar 2026

New Legionella testing selective agar plates launched by AnalytiChem

AnalytiChem, manufacturer of specialized laboratory equipment, reagents and consumables, has launched a new addition to its high-quality Redipor® microbiological prepared media portfolio.

From AnalytiChem 24 Mar 2026

Biodegradable sanitary pads made from water hyacinth pass safety and absorbency tests in new study

Researchers developed a biodegradable sanitary pad using water hyacinth fibers and cotton, transforming an invasive aquatic weed into a sustainable absorbent material. Laboratory tests showed strong fluid absorption, safe pH levels, low microbial contamination, and rapid biodegradation.

17 Mar 2026

Study reveals dual role of PFK enzyme in metabolism and cell cycle progression

A metabolic enzyme studied for over seven decades has a hidden second function - it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, according to a new study led by the University of Surrey.

16 Mar 2026

Study reveals how disordered proteins function without stable structure

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

13 Mar 2026

New catalog identifies dozens of plasma membrane repair proteins

In the evolutionary history of life, the ability of a cell to separate its inner world from the external environment was an important turning point.

10 Mar 2026

Transposable elements cause majority of lethal mutations in fruit flies

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

10 Mar 2026

New optovolution technique uses light to guide protein evolution

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

6 Mar 2026

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Scientists developed Evo 2, a large biological foundation model trained on about 9 trillion DNA base pairs that can analyse genomic sequences across bacteria, plants, and humans. The model predicts functional effects of genetic variants and can generate genome-scale DNA sequences, enabling new approaches to studying and designing biological systems.

5 Mar 2026