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New grant funds AI search for genetic targets to treat Alzheimer's

With a new $6.2 million, five-year grant from the National Institute on Aging, researchers at Case Western Reserve University will use artificial intelligence (AI) and machine learning to identify possible genetic targets to treat Alzheimer's disease.

15 Apr 2026

Loneliness is linked to higher risk of degenerative heart valve disease

Adults who reported feeling lonely had a higher risk of developing degenerative heart valve disease, even after accounting for traditional heart disease risk factors and genetics, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

15 Apr 2026

Metabolic syndrome doubles worldwide over two decades

A global study reveals a sharp rise in metabolic syndrome prevalence from 2000 to 2023, highlighting urgent public health challenges and regional disparities.

15 Apr 2026

Feeling lonely impacts memory without accelerating mental decline

Loneliness affects the memory of older adults but does not speed up mental decline over time, suggests data from a major European study tracking more than 10,000 people over seven years.

14 Apr 2026

Common osteoporosis drugs could slow or halt aneurysm progression

Aortic aneurysms are characterized by abnormal enlargement of the aorta, the primary artery responsible for carrying blood from the heart. Rupture often leads to sudden death, and currently, no effective drug therapies are available to halt disease progression.

14 Apr 2026

Microplastics lab studies may fail to reflect real-world exposure

Microplastics pose health risks, but lab studies often fail to reflect real-world exposure, highlighting critical gaps in toxicological research methodologies.

14 Apr 2026

Alzheimer's risk gene APOE4 impacts bone health in females

Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered that APOE4, the most common genetic risk factor for Alzheimer's disease, causes bone quality deficits specifically in female mice, through a mechanism that is invisible to standard imaging and can emerge as early as midlife.

13 Apr 2026

Supportive neighborhoods linked to slower cognitive decline in older immigrants

Older Chinese immigrants living in neighborhoods with greater access to community amenities, services and supportive infrastructure experienced slower cognitive decline over time, according to Rutgers Health researchers.

13 Apr 2026

Targeted therapy treats mixed histiocytosis following multiple skull relapses

Mixed histiocytosis (Langerhans cell histiocytosis [LCH] / Erdheim-Chester disease [ECD]) developing after treatment for initial skull LCH is not well recognized.

13 Apr 2026

Hepatologists effectively deliver palliative care to patients with liver disease

Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality of life.

13 Apr 2026

Moving more, sitting less, and sleeping well may lower dementia risk

Findings suggest that regular physical activity and adequate sleep may lower dementia risk, emphasizing the need for evidence-based lifestyle guidelines.

13 Apr 2026

Damon Runyon supports young scientists driving cancer research innovation

The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

11 Apr 2026

Study reveals immune aging differs significantly between men and women

Statistics show clear differences in the population's immune system according to sex: men are more susceptible to infections and cancers, while women have stronger immune responses, which translate, for example, into better responses to vaccines.

11 Apr 2026

Lung tumors shift identity making treatment more difficult

A new study co-led by the Institute for Systems Biology (ISB) shows that some lung cancers can change identity as they evolve, shifting from one cancer type to another in ways that may make them more aggressive and harder to treat.

10 Apr 2026

New collaboration targets muscle loss treatments for space missions

The Center for Myokine Convergence Research at Korea University College of Medicine (Director: Professor Hyeon Soo Kim, Department of Anatomy, Korea University College of Medicine) has signed a memorandum of understanding (MOU) with MFC to jointly develop therapeutics for muscle loss in astronauts.

10 Apr 2026

For many patients leaving the ICU, the struggle has only just begun

The accident happened in Pittsburgh on Nov. 16. Joseph Masterson, a lawyer who was just days from retiring at age 63, suffered cardiac arrest while driving, plowed into a guardrail, and lost consciousness.

10 Apr 2026

Large US study finds never-married adults face higher risk for most major cancers

A large US population-based study found that never-married adults had higher cancer incidence than ever-married adults across most cancer types, with the largest disparities seen in older adults and in Black men. The pattern was especially strong for HPV-related, tobacco-related, and several reproductive cancers, suggesting marital status may act as an important social marker of cancer risk.

9 Apr 2026

Higher optimism may lower dementia risk in older adults

Higher optimism in adults aged 70 and older was associated with a lower risk of developing dementia over up to 14 years of follow-up in the Health and Retirement Study. The association remained after adjustment for demographic factors, depression, health conditions, smoking, and physical activity, although the study was observational and cannot prove causation.

9 Apr 2026

Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

9 Apr 2026

High-quality plant-based diets linked to lower dementia risk

Eating a higher quality plant-based diet is associated with a lower risk of Alzheimer's disease and other related dementias compared to eating a lower quality plant-based diet, according to a study published April 8, 2026, in Neurology, the medical journal of the American Academy of Neurology.

8 Apr 2026