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Aptamer announces new data at ASGCT

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, presented new data on its Optimer therapeutic delivery vehicle for liver fibrosis at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting in New Orleans, LA (13-17 May 2025).

From Aptamer Group 16 May 2025

New candidate compounds show promise for Alzheimer's and pain treatment

A study published in the Journal of Medicinal Chemistry presents a new family of candidate compounds for the treatment of Alzheimer's disease and pain, which have shown promising effects in animal models.

14 May 2025

New glycopeptide antibiotic discovered to combat resistant bacteria

An international team of researchers, led by the University of Vienna and the Helmholtz Institute for Pharmaceutical Research Saarland, has discovered saarvienin A, a new type of glycopeptide antibiotic.

14 May 2025

BSO drug mimics anti-obesity effects of difficult sulfur amino acid restricted diet

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 7, 2025, titled "Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet."

13 May 2025

New study identifies wedelolactone as a potent topical treatment for psoriasis

Announcing a new publication for Acta Materia Medica journal. Psoriasis is a chronic inflammatory disorder for which phosphodiesterase-4 (PDE4) inhibitors have emerged as promising therapeutic agents due to an ability to regulate inflammatory signaling pathways.

13 May 2025

Collagen protein bars show promise for safe and effective weight loss

Research being presented at this year's European Congress on Obesity (ECO 2025) and published in the journal Nutrients indicates that collagen could be a safe and effective weight-loss supplement.

12 May 2025

Mice study sheds light on the mechanisms underlying sex differences in psychiatric conditions

Conditions such as Tourette syndrome (TS), schizophrenia, and Attention-Deficit/Hyperactivity Disorder (ADHD) have sex differences with unknown mechanisms.

12 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Unlocking the mechanism behind marine bacterium’s ability to clean up oil spills

The marine bacterium Alcanivorax borkumensis feeds on oil, multiplying rapidly in the wake of oil spills, and thereby accelerating the elimination of the pollution, in many cases.

10 May 2025

Most of today’s children could endure historic heatwaves as planet warms

A Nature study projects that millions born after 1960 will face unprecedented lifetime exposure (ULE) to climate extremes, such as heatwaves, droughts, and floods. The risks grow with global warming and disproportionately impact socioeconomically vulnerable populations.

8 May 2025

New AI approach speeds up antiviral discovery for human enterovirus 71

Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.

6 May 2025

Natural compound fisetin protects blood vessels from hardening

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 2, 2025, titled "Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK inhibition."

6 May 2025

Cannabis use during pregnancy linked to higher risk of infant complications

An updated systematic review finds that consuming cannabis while pregnant appears to increase the odds of preterm birth, low birth weight and infant death.

5 May 2025

NAD+ restoration improves mitochondrial function in Werner syndrome cells

A new research paper was published in Aging (Aging-US) on April 2, 2025, as the cover of Volume 17, Issue 4, titled "Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation."

2 May 2025

Sapio Sciences introduces Biorepository Management solution in Sapio Release 25.4

Sapio Sciences, the science-aware™ lab informatics platform, today announced Sapio Release 25.4, introducing a new Biorepository Management solution, enhanced sample management capabilities, and platform-wide enhancements designed to streamline lab operations and support high-throughput research environments.

From Sapio Sciences 2 May 2025

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

Researchers explore the medicinal role of curcumin in the treatment and prevention of neuroinflammation and metabolic disorders.

30 Apr 2025

New antiviral compounds show broad protection against COVID-19 variants

Novel Mpro inhibitors exhibit broad activity against SARS-CoV-2 and other coronaviruses.

30 Apr 2025

Machine learning uncovers promising drug leads against human enterovirus 71

Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.

29 Apr 2025

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Metrion Biosciences ("Metrion"), the specialist preclinical contract research organization (CRO) and a global leader in ion channel services, today announced the launch of its validated, high-throughput NaV1.9 screening assay to advance discovery and development of novel pain therapeutics.

28 Apr 2025

Anti-inflammatory drug can prevent and alleviate periodontal tissue damage

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage.

28 Apr 2025