Neurodegenerative Diseases News and Research

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Exercise promotes nerve growth at the cellular level

There's no doubt that exercise does a body good. Regular activity not only strengthens muscles but can bolster our bones, blood vessels, and immune system.

12 Nov 2024

Revolutionary AI predicts aging and disease from DNA patterns

Researchers developed CpGPT, a novel foundation model for DNA methylation analysis that captures sequence, positional, and epigenetic context to predict aging and disease risks. This model offers breakthroughs in imputing missing data and improving mortality and morbidity predictions.

11 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

C-Path announces important leadership appointments in neurology and Alzheimer's research

Critical Path Institute (C-Path) today announced key leadership appointments: Diane Stephenson, Ph.D., has been promoted to Vice President of Neurology, and Nadine Tatton, Ph.D., has been welcomed as the new Executive Director of C-Path's Critical Path for Alzheimer's Disease (CPAD) Consortium.

7 Nov 2024

Understanding the role of neuroimmune cells in brain health and disease

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

6 Nov 2024

Saturated fats accelerate neurodegeneration in multiple sclerosis

Targeting ceramide synthase enzymes may reduce multiple sclerosis severity by limiting ceramide C16 synthesis, offering potential neuroprotective strategies.

6 Nov 2024

Mice tails play a key role in preventing falls and improving balance

Why do mice have tails? The answer to this is not as simple as you might think. New research from the Okinawa Institute of Science and Technology (OIST) has shown that there's more to the humble mouse tail than previously assumed.

6 Nov 2024

Ancient herb shows promise in fighting dementia

Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine.

6 Nov 2024

Space-grown stem cells show promise for accelerating biotherapies

Stem cells grown in microgravity aboard the International Space Station (ISS) have unique qualities that could one day help accelerate new biotherapies and heal complex disease, two Mayo Clinic researchers say.

4 Nov 2024

Noninvasive brain stimulation shows promise for enhancing navigation skills in cognitive impairment

A study on deep brain stimulation reveals its impact on spatial navigation, highlighting potential therapeutic avenues for cognitive deficits in aging.

4 Nov 2024

New study identifies potential treatment for tauopathies using carbonic anhydrase inhibitors

Carbonic anhydrase inhibitors show potential in reducing tau protein buildup, offering new therapeutic avenues for neurodegenerative diseases like tauopathies.

4 Nov 2024

Carbonic anhydrase inhibitors clear tau build-up in zebrafish models of tauopathies

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer’s disease.

4 Nov 2024

Researchers link polyphosphate to protective role in neurodegenerative disease fibrils

Research led by the University of Michigan has provided compelling evidence that could solve a fundamental mystery in the makeup of fibrils that play a role in Alzheimer’s, Parkinson’s and other neurodegenerative diseases

3 Nov 2024

Huntington’s disease symptoms reduced by new peptide-polymer therapy

Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the brain.

3 Nov 2024

Research uncovers new mechanism in protein aggregation linked to Parkinson's disease

A team of researchers at Kumamoto University has uncovered a groundbreaking mechanism in the formation of harmful protein aggregates that lead to neurodegenerative diseases such as Parkinson's Disease.

1 Nov 2024

Glaucoma medication may help prevent Alzheimer's-related tau build-up

1 Nov 2024

Research uncovers potential role of polyphosphate in neurodegenerative diseases

Research led by the University of Michigan has provided compelling evidence that could solve a fundamental mystery in the makeup of fibrils that play a role in Alzheimer's, Parkinson's and other neurodegenerative diseases.

1 Nov 2024

Brain actively engages with immune system to maintain health

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue.

1 Nov 2024

Space-based research uncovers key to cancer cell survival

In October, we think pink, and for a good reason - one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis. Biotechnology startup MicroQuin leveraged the International Space Station (ISS) National Laboratory to grow 3D breast and prostate cancer cell cultures to learn more about how these cancers develop and grow.

29 Oct 2024

C. elegans model system accelerates discovery of amyloid inhibitors

An international team led by researchers at the University of Toronto has developed an efficient and robust system, using the C. elegans nematode, to screen for compounds that can stop the growth of amyloid proteins.

28 Oct 2024

Neurodegenerative Diseases News and Research

Exercise promotes nerve growth at the cellular level

Revolutionary AI predicts aging and disease from DNA patterns

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

C-Path announces important leadership appointments in neurology and Alzheimer's research

Understanding the role of neuroimmune cells in brain health and disease

Saturated fats accelerate neurodegeneration in multiple sclerosis

Mice tails play a key role in preventing falls and improving balance

Ancient herb shows promise in fighting dementia

Space-grown stem cells show promise for accelerating biotherapies

Noninvasive brain stimulation shows promise for enhancing navigation skills in cognitive impairment

New study identifies potential treatment for tauopathies using carbonic anhydrase inhibitors

Carbonic anhydrase inhibitors clear tau build-up in zebrafish models of tauopathies

Researchers link polyphosphate to protective role in neurodegenerative disease fibrils

Huntington’s disease symptoms reduced by new peptide-polymer therapy

Research uncovers new mechanism in protein aggregation linked to Parkinson's disease

Glaucoma medication may help prevent Alzheimer's-related tau build-up

Research uncovers potential role of polyphosphate in neurodegenerative diseases

Brain actively engages with immune system to maintain health

Space-based research uncovers key to cancer cell survival

C. elegans model system accelerates discovery of amyloid inhibitors

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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