Precision Medicine News and Research

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Baylor study sheds light on role of CDKL1 and CDKL2 in neurodevelopmental disorders

CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures.

14 Mar 2025

Bioenergetic age could predict Alzheimer's disease risk

A person's "bioenergetic age"-or how youthfully their cells generate energy-might be a key indicator of whether they're at risk of developing Alzheimer's disease, new research from Weill Cornell Medicine shows.

14 Mar 2025

CityUHK leads groundbreaking project to develop new platform for early cancer detection

Cancer continues to be a leading cause of mortality worldwide, highlighting the urgent need to develop more advanced, efficient, and early detection methods.

13 Mar 2025

Researchers discover race-associated molecular differences in pancreatic tumors

Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic cancer respond to immunotherapies.

12 Mar 2025

Examining skin cancer risk perceptions and reported sunburns among U.S. adults

Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs the U.S. approximately $8.9 billion annually.

12 Mar 2025

Gender gaps in peripheral vascular disease impact diagnosis and treatment

The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

Exploring the use of AI for precision hypertension management in diabetes care

Pennington Biomedical Research Center's Dr. Yun Shen will lead a team to explore the use of AI for precision hypertension management in Type-2 diabetes care.

10 Mar 2025

Breakthrough drug combination targets KRAS mutation in lung cancer

A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib-an FDA-approved drug in the market-and an experimental drug called FGTI-2734, which could make precision medicine more effective for patients with a highly resistant form of lung cancer.

10 Mar 2025

Scientists discover key molecular switch for blood stem cell regeneration

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators.

10 Mar 2025

UF researchers develop AI tool to tackle ancestral bias in precision medicine

University of Florida researchers are addressing a critical gap in medical genetic research - ensuring it better represents and benefits people of all backgrounds.

10 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) representing the most prevalent subtypes of non-small cell lung cancer (NSCLC).

8 Mar 2025

EZH2 inhibition offers hope for fighting treatment-resistant cancers

The critical role of EZH2, an essential epigenetic regulator, in cancer progression and treatment is underscored in this new review article published in Genes & Diseases.

8 Mar 2025

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by regulating hepatic lipid homeostasis and cellular maintenance processes.

6 Mar 2025

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their implications in various diseases.

5 Mar 2025

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that drive tumor development.

5 Mar 2025

Precision Medicine News and Research

Baylor study sheds light on role of CDKL1 and CDKL2 in neurodevelopmental disorders

Bioenergetic age could predict Alzheimer's disease risk

CityUHK leads groundbreaking project to develop new platform for early cancer detection

Researchers discover race-associated molecular differences in pancreatic tumors

Examining skin cancer risk perceptions and reported sunburns among U.S. adults

Gender gaps in peripheral vascular disease impact diagnosis and treatment

Novel regulators in digestive tract disease progression and treatment

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

Study reveals TCM-Based strategies for ferroptosis modulation

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

Exploring the use of AI for precision hypertension management in diabetes care

Breakthrough drug combination targets KRAS mutation in lung cancer

Scientists discover key molecular switch for blood stem cell regeneration

UF researchers develop AI tool to tackle ancestral bias in precision medicine

Understanding the role of LSD1 in cellular processes and disease

Unraveling the genetic differences between LUAD and LUSC in lung cancer

EZH2 inhibition offers hope for fighting treatment-resistant cancers

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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