Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Charles Bonnet syndrome: an interview with Dr. Dominic ffytche

Charles Bonnet syndrome is the name we give to the visual hallucinations associated with eye disease. There are lots of different causes of visual hallucinations. Many different medical problems and medications can cause them, but, when the cause is eye disease, it's referred to as Charles Bonnet Syndrome after Charles Bonnet, who was a natural philosopher in the 18th century.

2 Nov 2015

Penn Medicine's Gordon Baltuch performs 1,000th deep brain stimulation procedure

Deep brain stimulation (DBS) improves many of the motor symptoms of Parkinson's disease (PD) and is a life-alerting surgery for many patients. Penn Medicine's Gordon Baltuch, MD, a professor of Neurosurgery and director of the Penn Center for Functional and Restorative Neurosurgery, is one of the most prolific DBS surgeons in the world, having recently performed his 1,000th procedure, marking an important milestone for Baltuch and Penn Medicine.

31 Oct 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

Routine clinical features may aid BVFTD diagnostic accuracy

Researchers have identified clinical features that can help determine which patients assessed for behavioural variant frontotemporal dementia are most likely to actually have the condition.

30 Oct 2015

FAU, Max Planck ink new agreement to recruit and retain promising scientists

Florida Atlantic University, the Max Planck Florida Institute for Neuroscience and the Max Planck Society based in Germany, have signed an innovative agreement to facilitate a research and education program that will recruit promising scientists to MPFI and FAU.

30 Oct 2015

Transition Therapeutics Ireland signs agreement for investigator-led TT701 Phase 2 clinical study

Transition Therapeutics Inc. announced today that Transition Therapeutics Ireland Limited has entered into an agreement for an investigator-led clinical study of drug candidate, TT701, with Brigham and Women's Hospital.

30 Oct 2015

Older women who complain of memory problems may experience thinking impairment decades later

New research suggests that older women who complain of memory problems may be at higher risk for experiencing diagnosed memory and thinking impairment decades later. The study is published in the October 28, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Oct 2015

Rush awarded $2.45 million grant to support quality care for older Americans

Rush University Medical Center has received a three-year, $2.45 million grant from the U.S. Health Resources and Services Administration to support quality care for older Americans. Rush is one of only 44 health and education institutions in the country that the HRSA chose to become a Geriatrics Workforce Enhancement Program, which supports training and education that leads to better care for older adults.

29 Oct 2015

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Dementia specialists and PET imaging providers can now register to participate in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS) Study at Ideas-Study.org.

29 Oct 2015

Jet lag-like sleep disruptions promote memory problems, chemical alterations in the brain

Chemical changes in brain cells caused by disturbances in the body's day-night cycle may be a key underlying cause of the learning and memory loss associated with Alzheimer's disease, according to a University of California, Irvine study.

29 Oct 2015

Cholinesterase inhibitor delays nursing home admission in late-stage AD

The withdrawal of donepezil from patients with Alzheimer’s disease as they reach the moderate-to-severe stages of the disease doubles their risk of being placed in a nursing home within the first 12 months, secondary analysis of the DOMINO-AD trial indicates.

28 Oct 2015

Changes in lifestyle could reduce Alzheimer's disease risk

Changes in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University's Network Aging Research, who examined the data from two independent epidemiological studies. Carriers of the ApoE4 genetic risk factor for Alzheimer's may be able to reduce their increased risk of cognitive decline by reducing their cholesterol level, especially if they also suffer from cardiovascular disease.

27 Oct 2015

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Massachusetts General Hospital investigators have discovered a mechanism behind the spread of neurofibrillary tangles - one of the two hallmarks of Alzheimer's disease - through the brains of affected individuals.

27 Oct 2015

Lewy Body Composite Risk Score detects LBD and Parkinson's disease dementia in three minutes

Although Lewy Body disease (LBD) is the second-most-common degenerative disease after Alzheimer's disease, it's not exactly a household name. It affects more than 1.3 million Americans, is poorly recognized, and diagnosis is often significantly delayed. Patients with LBD simultaneously experience losses in cognitive function, mobility and behavior.

27 Oct 2015

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

Benzodiazepines and related drugs are initiated frequently in persons with Alzheimer's disease already before the diagnosis, and their use becomes even more common after the diagnosis, shows a recent study from the University of Eastern Finland.

26 Oct 2015

Spatial grid pattern in brain region is altered in young adults with Alzheimer's risk

Young adults with genetically increased Alzheimer's risk have altered activation patterns in a brain region that is crucial for spatial navigation.

23 Oct 2015

New technique helps study protein changes in brain tissue of Alzheimer's patients

Using 10-year-old archival brain tissue from patients with Alzheimer's disease, a research team from NYU Langone Medical Center has developed a novel method to examine the structure and function of proteins at the cell level -- providing greater means to study protein changes found in Alzheimer's disease.

23 Oct 2015

Findings suggest a potential "early warning" detection system for Alzheimer's disease

The findings suggest a potential "early warning" detection system for Alzheimer's disease, even in young and asymptomatic individuals.

23 Oct 2015

New research may have profound impact on future development of anti-depressant medications

Major depression, which afflicts one in six people at some point in their life, is the leading global cause of disability - surpassing cardiovascular and respiratory diseases, cancer and HIV/AIDS combined.

22 Oct 2015

Alzheimer's Disease News and Research

Further Reading

Charles Bonnet syndrome: an interview with Dr. Dominic ffytche

Penn Medicine's Gordon Baltuch performs 1,000th deep brain stimulation procedure

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Routine clinical features may aid BVFTD diagnostic accuracy

FAU, Max Planck ink new agreement to recruit and retain promising scientists

Transition Therapeutics Ireland signs agreement for investigator-led TT701 Phase 2 clinical study

Older women who complain of memory problems may experience thinking impairment decades later

Rush awarded $2.45 million grant to support quality care for older Americans

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Jet lag-like sleep disruptions promote memory problems, chemical alterations in the brain

Cholinesterase inhibitor delays nursing home admission in late-stage AD

Changes in lifestyle could reduce Alzheimer's disease risk

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Lewy Body Composite Risk Score detects LBD and Parkinson's disease dementia in three minutes

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

Spatial grid pattern in brain region is altered in young adults with Alzheimer's risk

New technique helps study protein changes in brain tissue of Alzheimer's patients

Findings suggest a potential "early warning" detection system for Alzheimer's disease

New research may have profound impact on future development of anti-depressant medications

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