Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

More research needed before recommending antidepressants, Alzheimer's disease drugs for stroke recovery: Study

Evidence is mounting that drugs used to treat depression and Alzheimer's disease also can help patients recover from strokes. But there are conflicting findings from studies of these and other drugs given to recovering stroke patients.

22 Oct 2015

Plaques impair memory formation in Alzheimer’s disease during sleep

Alzheimer’s patients frequently suffer from sleep disorders, mostly even before they become forgetful. Furthermore, it is known that sleep plays a very important role in memory formation.

22 Oct 2015

Novel method provides greater means to study protein changes in Alzheimer's disease

Using 10-year-old archival brain tissue from patients with Alzheimer's disease, a research team from NYU Langone Medical Center has developed a novel method to examine the structure and function of proteins at the cell level--providing greater means to study protein changes found in Alzheimer's disease.

22 Oct 2015

Restoring memory in aging mice

A new study, led by scientists at The Scripps Research Institute (TSRI), the Veterans Affairs San Diego Healthcare System (VA) and University of California (UC) San Diego School of Medicine shows that increasing a crucial cholesterol-binding membrane protein in nerve cells (neurons) within the brain can improve learning and memory in aged mice.

22 Oct 2015

Celiac patients at no increased risk for dementia, study finds

A new and comprehensive study by investigators at the Celiac Disease Center at Columbia University Medical Center has found that celiac patients are at no increased risk for dementia before or after their diagnosis of celiac disease.

20 Oct 2015

NAM announces election of three new members from UC San Diego School of Medicine

The National Academy of Medicine announced today the election of three new members from University of California, San Diego School of Medicine: Napoleone Ferrara, MD; Christopher K. Glass, MD, PhD; and Roberto Malinow, MD, PhD. Election to NAM is considered among the highest honors in the fields of health and medicine.

20 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

OSU discovery sheds new light on how proteins fold

Biochemists at Oregon State University have made a fundamental discovery about protein structure that sheds new light on how proteins fold, which is one of the most basic processes of life.

19 Oct 2015

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

19 Oct 2015

OHSU designs new iPhone app to advance melanoma research

Oregon Health & Science University today released an iPhone app designed to advance melanoma research by giving users the ability to accurately measure and monitor moles, and contribute photos of how their potential trouble spots evolve over time.

16 Oct 2015

Researchers uncover how small heat shock protein interacts with other proteins

In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich and the Helmholtz Zentrum Muenchen have now uncovered how the protein interacts with other proteins.

15 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

UTHealth biochemists expose structures of IP3R calcium channels

Calcium is a crucial element in the body that controls thought, movement and other bodily functions. These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments. For years, scientists have been unsure how calcium ion channels function.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

Antipsychotic drugs more frequently used in Alzheimer's disease patients, new study finds

Antipsychotic drugs are initiated in patients with Alzheimer's disease (AD) more frequently than in the general population - already 2-3 years before the Alzheimer's diagnosis, according to a new study from the University of Eastern Finland.

14 Oct 2015

Antipsychotics initiated frequently and used for long term in Alzheimer's patients

Antipsychotic drugs are initiated in patients with Alzheimer's disease (AD) more frequently than in the general population – already 2–3 years before the Alzheimer's diagnosis, according to a new study from the University of Eastern Finland. Most commonly, antipsychotics were initiated during the six months following the Alzheimer's diagnosis; however, the incidence of new antipsychotic users was high also later on. The results were published in British Journal of Psychiatry.

14 Oct 2015

Brain areas linked to social behaviors underdeveloped in youths with high functioning ASD

A team of UCLA scientists has found that brain areas linked to social behaviors are both underdeveloped and insufficiently networked in youths with high functioning autism spectrum disorder (ASD) compared to study participants without ASD.

14 Oct 2015

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Researchers at the University of Washington have used a noninvasive light-based imaging technology to literally see inside the living brain, providing a new tool to study how diseases like dementia, Alzheimer's, and brain tumors change brain tissue over time.

13 Oct 2015

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

Today, GENALICE is setting a new standard for ultra-fast and highly reliable detection of all DNA changes in large patient cohorts. In a one-hour online event, the complete genomes of 800 Alzheimer Disease (AD) patients were processed, and by ingeniously using the aggregate information from the complete group, detection of DNA changes, or variants, in individual patients was enhanced.

13 Oct 2015

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

13 Oct 2015

Alzheimer's Disease News and Research

Further Reading

More research needed before recommending antidepressants, Alzheimer's disease drugs for stroke recovery: Study

Plaques impair memory formation in Alzheimer’s disease during sleep

Novel method provides greater means to study protein changes in Alzheimer's disease

Restoring memory in aging mice

Celiac patients at no increased risk for dementia, study finds

NAM announces election of three new members from UC San Diego School of Medicine

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

OSU discovery sheds new light on how proteins fold

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

OHSU designs new iPhone app to advance melanoma research

Researchers uncover how small heat shock protein interacts with other proteins

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

UTHealth biochemists expose structures of IP3R calcium channels

Having a high stress job may increase risk of stroke

Antipsychotic drugs more frequently used in Alzheimer's disease patients, new study finds

Antipsychotics initiated frequently and used for long term in Alzheimer's patients

Brain areas linked to social behaviors underdeveloped in youths with high functioning ASD

UW researchers use noninvasive light-based imaging technology to see inside the living brain

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

GENALICE’s Population Calling analysis module improves diagnosis, treatment of complex DNA diseases

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