Therapeutics News and Research

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Integrin-binding peptide ATN-161: Potential COVID-19 treatment

Now, a new study by researchers at Tulane University and published on the preprint server bioRxiv* in June 2020 reports the potential role of an integrin inhibitor ATN-161 to prevent ACE2-S protein binding.

17 Jun 2020

Penn’s CEET receives $8 million grant for environmental health research

The Center of Excellence in Environmental Toxicology at the University of Pennsylvania received an $8 million grant, to be distributed over the next five years, from the National Institute of Environmental Health Sciences, a renewal of its P30 Environmental Health Sciences Core Center grant.

17 Jun 2020

UConn researchers tackle a vexing problem in the development of vaccines

Researchers at UConn's Center of Excellence in Vaccine Research have made a breakthrough in vaccine development for a common and difficult to treat pneumonia-causing pathogen. Their research was recently published in the Nature Partner Journal - Vaccines.

17 Jun 2020

New test could guide and improve treatment options for women with deadly ovarian cancer

University of British Columbia researchers have led an international team in developing a new test to better diagnose different types of ovarian cancer, a tool that could one day guide and improve treatment options for women diagnosed with the most common and deadliest form of the disease.

17 Jun 2020

USC researchers unlock fatal vulnerability in many cancer cells

Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth.

17 Jun 2020

'Microbial dark matter' can affect cholesterol levels in humans

In the darkest parts of the world where light fails to block out the unfathomable bounty of the stars, look up. There are still fewer specks illuminating the universe than there are bacteria in the world, hidden from sight, a whole universe inside just one human gut.

17 Jun 2020

Two clinical trials use low-dose X-rays to treat COVID-19 pneumonia

Previous studies have shown that low-dose, whole lung radiation in the form of X-rays can effectively treat severe pneumonia, with minimal side effects.

17 Jun 2020

Nanosponges could attack and neutralize SARS-COV-2 virus

Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.

17 Jun 2020

BIA Separations launches novel PrimaS ligand technology to facilitate development of advanced therapies

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of its novel PrimaS ligand technology.

17 Jun 2020

How antibodies neutralize SARS-CoV-2 in convalescent patients

A new study by researchers from the United Kingdom and Taiwan and published on the preprint server bioRxiv in June 2020 describes the structural basis for the neutralizing effect of the SARS-CoV-2 antibody on the virus. This also indicates a possible therapeutic molecule by identifying its binding epitope as possibly a major neutralizing site.

16 Jun 2020

Two potent small molecules appear to suppress tumor growth in multiple cancers

City of Hope scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple cancers even when other treatments cease to work, possibly due to the development of drug resistance.

16 Jun 2020

Common cholesterol drugs could slow breast cancer metastasis to the brain

A new study from the University of Notre Dame shows drugs used to treat high cholesterol could interfere with the way breast cancer cells adapt to the microenvironment in the brain, preventing the cancer from taking hold.

16 Jun 2020

Researchers receive federal funding to rapidly repurpose FDA-approved drugs for COVID-19

Researchers at the University of Maryland School of Medicine will be partnering on an agreement funded by the federal government's Defense Advanced Research Projects Agency (DARPA) to rapidly test hundreds of drugs, approved and marketed for other conditions, to see whether any can be repurposed to prevent or treat COVID-19.

16 Jun 2020

Novel antisense drug shows promise to improve health of people with NAFLD

Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San Diego School of Medicine reports that inhibition of a key enzyme safely and effectively improved the health of persons with non-alcoholic fatty liver disease, a chronic metabolic disorder that affects hundreds of millions of people worldwide.

16 Jun 2020

First National Preclinical Imaging Centre established in Ireland to enhance medical research

A new National Preclinical Imaging Centre which will provide enhanced research data to inform new clinical trials that aim to improve patient outcomes, has been awarded funding of €3.4 million under the Science Foundation Ireland Research Infrastructure Programme.

16 Jun 2020

New wearable patch may provide improved treatment experience for melanoma patients

Conventional melanoma therapies, including chemotherapy and radiotherapy, suffer from the toxicity and side effects of repeated treatments due to the aggressive and recurrent nature of melanoma cells.

16 Jun 2020

Cascade Chemistry selected to help speed clinical testing of promising investigational drug for COVID-19

Cascade Chemistry, a leading contract research and manufacturing organization serving the pharmaceutical, materials, and chemical industries, today announced that it has been selected to produce the active pharmaceutical ingredient for clinical trial supplies of RBT-9, an investigational therapy entering a Phase 2 trial for the treatment of COVID-19 patients who are at high risk of deteriorating health due to age or comorbid conditions such as kidney or cardiovascular disease.

16 Jun 2020

Micro-dystrophin gene therapy can improve outcomes in children with Duchenne muscular dystrophy

Researchers from Nationwide Children's Hospital have published in JAMA Neurology results from the first four patients treated in the first clinical trial of systemic delivery of micro-dystrophin gene therapy in children with Duchenne muscular dystrophy (DMD) - and initial findings suggest that the therapy can provide functional improvement that is greater than that observed under the standard of care.

16 Jun 2020

Antisense Therapeutics: Poster presentation on the Muscular Dystrophy Association Virtual Conference 2020 website

Antisense Therapeutics, an Australian biopharmaceutical company developing and commercializing antisense pharmaceuticals for unmet need in rare diseases announces a virtual poster presentation on the Muscular Dystrophy Association Virtual 2020 Conference website.

15 Jun 2020

Glycans "lock and load" the SARS-CoV-2 spike protein for infection

A new study by scientists from the University of California San Diego, USA and Maynooth University, Ireland and published on the preprint server bioRxiv* in June 2020 reports preliminary results showing that the spike protein of the SARS-CoV-2, as well as its glycan coat, has “hitherto unseen functional and structural” properties. These may be useful in designing novel therapeutics to target this molecule.

14 Jun 2020

Therapeutics News and Research

Integrin-binding peptide ATN-161: Potential COVID-19 treatment

Penn’s CEET receives $8 million grant for environmental health research

UConn researchers tackle a vexing problem in the development of vaccines

New test could guide and improve treatment options for women with deadly ovarian cancer

USC researchers unlock fatal vulnerability in many cancer cells

'Microbial dark matter' can affect cholesterol levels in humans

Two clinical trials use low-dose X-rays to treat COVID-19 pneumonia

Nanosponges could attack and neutralize SARS-COV-2 virus

BIA Separations launches novel PrimaS ligand technology to facilitate development of advanced therapies

How antibodies neutralize SARS-CoV-2 in convalescent patients

Two potent small molecules appear to suppress tumor growth in multiple cancers

Common cholesterol drugs could slow breast cancer metastasis to the brain

Researchers receive federal funding to rapidly repurpose FDA-approved drugs for COVID-19

Novel antisense drug shows promise to improve health of people with NAFLD

First National Preclinical Imaging Centre established in Ireland to enhance medical research

New wearable patch may provide improved treatment experience for melanoma patients

Cascade Chemistry selected to help speed clinical testing of promising investigational drug for COVID-19

Micro-dystrophin gene therapy can improve outcomes in children with Duchenne muscular dystrophy

Antisense Therapeutics: Poster presentation on the Muscular Dystrophy Association Virtual Conference 2020 website

Glycans "lock and load" the SARS-CoV-2 spike protein for infection

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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