Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer's disease, according to a new study published in the September 2, 2015, online version of Neurology, the medical journal of the American Academy of Neurology.

3 Sep 2015

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

Genes are not only important for regular memory performance, but also for the development of Alzheimer's disease. Researchers at the University of Basel now identified a specific group of genes that plays a central role in both processes. This group of molecules controls the concentration of calcium ions inside the cell.

3 Sep 2015

UC Santa Barbara neuroscientists uncover mechanism of Alzheimer's progression

Medical research has yet to discover an Alzheimer's treatment that effectively slows the disease's progression, but neuroscientists at UC Santa Barbara may have uncovered a mechanism by which onset can be delayed by as much as 10 years.

2 Sep 2015

Amgen, Novartis collaborate for Alzheimer's disease and migraine programs

Amgen today announced a neuroscience collaboration with Novartis in the areas of Alzheimer's disease and migraine. The collaboration accelerates Amgen's potential entry into Alzheimer's disease by teaming up with Novartis on a differentiated and genetically validated Alzheimer's disease program directed at genetically predisposed individuals at risk of developing Alzheimer's disease.

2 Sep 2015

Dementia brain imaging is helpful but not definitive, shows new research

MRI scans and other tools to detect and diagnose dementia are helpful but not definitive - according to new research from the University of East Anglia.

2 Sep 2015

Breakthrough discovery provides better understanding of Alzheimer’s disease

Alzheimer's disease is associated with the appearance of characteristic neurotoxic protein aggregates in various regions in the brain.

1 Sep 2015

Newly discovered prion causes Multiple System Atrophy

Multiple System Atrophy (MSA), a neurodegenerative disorder with similarities to Parkinson's disease, is caused by a newly discovered type of prion, akin to the misfolded proteins involved in incurable progressive brain diseases such Creutzfeldt-Jakob Disease (CJD), according to two new research papers led by scientists at UC San Francisco.

1 Sep 2015

Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Resverlogix Corp. is pleased to announce that Dr. Norman Wong, chief scientific officer of Resverlogix Corp. presented new data at the European Society of Cardiology (ESC) Congress 2015 in a poster presentation titled: "RVX-208, an orally active BET inhibitor, lowers CVD risk by activities beyond raising ApoA-I/HDL."

31 Aug 2015

Cholinergic neurons in basal forebrain broadcast message throughout the cerebral cortex

When a large combat unit, widely dispersed in dense jungle, goes to battle, no single soldier knows precisely how his actions are affecting the unit's success or failure. But in modern armies, every soldier is connected via an audio link that can instantly receive broadcasts - reporting both positive and negative surprises - based on new intelligence. The real-time broadcasts enable dispersed troops to learn from these reports and can be critical since no solider has an overview of the entire unit's situation.

28 Aug 2015

Despite increased life expectancy, British people suffer from more medical ailments

People in the UK are living longer but are coping with more medical ailments causing illness or disability in their older years, according to a major new international study published in The Lancet today (Thursday 27 August).

28 Aug 2015

Researchers find fatty acid deposits in brains of Alzheimer's patients

People with Alzheimer's disease have fat deposits in the brain. For the first time since the disease was described 109 years ago, researchers affiliated with the University of Montreal Hospital Research Centre (CRCHUM) have discovered accumulations of fat droplets in the brain of patients who died from the disease and have identified the nature of the fat.

28 Aug 2015

Researchers uncover important cellular functions that help regulate inflammation

Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation -- a discovery that could have important implications for the treatment of allergies, heart disease, and certain forms of cancer.

28 Aug 2015

Brain scans may help predict patients' response to antipsychotic drug treatment

Investigators at The Feinstein Institute for Medical Research have discovered that brain scans can be used to predict patients' response to antipsychotic drug treatment. The findings are published online in the latest issue of The American Journal of Psychiatry.

28 Aug 2015

Brain cells in Parkinson's disease die prematurely, burning out like an overheating motor

The death of brain cells in Parkinson's disease may be caused by a form of cellular energy crisis in neurons that require unusually high quantities of energy to carry out their job of regulating movement, researchers at the University of Montreal reported today.

28 Aug 2015

Alzheimer's Association urges people to participate in ‘Walk to End Alzheimer's’

The Alzheimer's Association® is calling on people to "get in the Purple Zone" and get behind the cause that affects more than 5 million people in the U.S.

28 Aug 2015

Experimental gene therapy may prevent neuronal degeneration in patients with Alzheimer's disease

Degenerating neurons in patients with Alzheimer's disease (AD) measurably responded to an experimental gene therapy in which nerve growth factor (NGF) was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.

28 Aug 2015

Key modifiable Alzheimer’s risk factors pinpointed

A meta-analysis has identified the key modifiable factors associated with an increased or decreased risk of Alzheimer’s disease.

27 Aug 2015

Isolated tauopathy ‘surprisingly common’ in AD dementia

A study shows that about a quarter of people with clinically diagnosed mild or moderate Alzheimer’s disease have only minimal β-amyloid deposition on autopsy.

27 Aug 2015

Dementia sufferers may begin to lose awareness of memory problems 2-3 years before onset

People who will develop dementia may begin to lose awareness of their memory problems two to three years before the actual onset of the disease, according to a new study published in the August 26, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Aug 2015

Common gene mutation may cause brain damage associated with ALS and FTD

Johns Hopkins researchers say they have discovered some of the first steps in how a very common gene mutation causes the brain damage associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

27 Aug 2015

Alzheimer's Disease News and Research

Further Reading

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

UC Santa Barbara neuroscientists uncover mechanism of Alzheimer's progression

Amgen, Novartis collaborate for Alzheimer's disease and migraine programs

Dementia brain imaging is helpful but not definitive, shows new research

Breakthrough discovery provides better understanding of Alzheimer’s disease

Newly discovered prion causes Multiple System Atrophy

Resverlogix presents new data on RVX-208 orally active BET inhibitor at ESC Congress 2015

Cholinergic neurons in basal forebrain broadcast message throughout the cerebral cortex

Despite increased life expectancy, British people suffer from more medical ailments

Researchers find fatty acid deposits in brains of Alzheimer's patients

Researchers uncover important cellular functions that help regulate inflammation

Brain scans may help predict patients' response to antipsychotic drug treatment

Brain cells in Parkinson's disease die prematurely, burning out like an overheating motor

Alzheimer's Association urges people to participate in ‘Walk to End Alzheimer's’

Experimental gene therapy may prevent neuronal degeneration in patients with Alzheimer's disease

Key modifiable Alzheimer’s risk factors pinpointed

Isolated tauopathy ‘surprisingly common’ in AD dementia

Dementia sufferers may begin to lose awareness of memory problems 2-3 years before onset

Common gene mutation may cause brain damage associated with ALS and FTD

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