Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Targeted breast cancer therapy shows 'encouraging' results

Researchers have developed a targeted therapy that may significantly increase the survival of pre-menopausal women with advanced breast cancer

3 Jun 2019

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Neoadjuvant, or pre-surgical, treatment with nivolumab plus ipilimumab resulted in an overall major pathologic response rate of 33 percent of treated patients with early-stage, resectable non-small cell lung cancers, meaning these patients had less than or equal to 10 percent viable tumor remaining at surgery.

3 Jun 2019

International clinical study of new drug to treat advanced prostate cancers yields promising results

Today the New England Journal of Medicine published the first results of a phase III international clinical study called TITAN (National Clinical Trials Number 02489318), which evaluated the effectiveness and safety of a new drug, apalutamide, to treat advanced prostate cancers.

3 Jun 2019

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years - and 25% of patients whose tumor cells had a specific protein lived at least that long.

3 Jun 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

Drug therapy may delay onset of myeloma symptoms, finds study

The largest randomized trial involving smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of myeloma symptoms, according to Mayo Clinic researchers.

3 Jun 2019

Only few prostate cancer patients choosing active surveillance follow monitoring guidelines

Preliminary results from a University of North Carolina Lineberger Comprehensive Cancer Center study found that just 15 percent of a group of men in North Carolina with early-stage prostate cancer who choose active surveillance instead of treatment followed the recommended monitoring guidelines.

3 Jun 2019

A new approach to predict complications after surgery for patients with larynx cancer

A technique that illuminates blood flow during surgery predicted which head and neck cancer patients were likely to have issues with wound healing. It could enable surgeons to make adjustments during surgery or recovery to improve outcomes.

31 May 2019

NCCN and AstraZeneca collaborate to improve care processes for lung cancer patients

The National Comprehensive Cancer Network Oncology Research Program and AstraZeneca, a global, science-led biopharmaceutical company, are collaborating to seek proposals for improving care processes for patients with unresectable stage III and stage IV non-small cell lung cancer.

31 May 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

Study highlights the need to educate oncologists about molecular profiling

A questionnaire aimed at assessing how well community oncologists understand "molecular profiling" results from tumor specimens found that 69 percent of participants either said they don't know the answers, or they responded incorrectly.

31 May 2019

Women in low- and middle-income countries need radiotherapy to treat their cervical cancer

A first of its kind study is reporting that millions of women in low- and middle-income countries will need life-saving radiotherapy to treat their cervical cancer, despite the growth of essential human papilloma virus vaccination prevention programs.

29 May 2019

Surgery can be beneficial for one type of primary central nervous system lymphoma

Through a systematic review of published studies going back 50 years, Johns Hopkins Medicine researchers say they have identified a distinct subtype of primary central nervous system lymphoma that should be considered for surgical removal, suggesting a major shift in how this type of tumor is evaluated and managed.

From Johns Hopkins Medicine 29 May 2019

Researchers develop new artificial intelligence tools to find cell’s true identity

Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes.

From Johns Hopkins Medicine 29 May 2019

New laboratory test has potential to accurately predict spread of breast cancer

Researchers at The Johns Hopkins University and other institutions report that a new laboratory test that induces cancer cells to squeeze through narrow spaces has the potential to accurately predict which breast cancers and other solid tumors are likely to spread, or metastasize, to other sites.

From Johns Hopkins Medicine 29 May 2019

Oncology News and Research

Further Reading

Targeted breast cancer therapy shows 'encouraging' results

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

International clinical study of new drug to treat advanced prostate cancers yields promising results

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Drug therapy may delay onset of myeloma symptoms, finds study

Only few prostate cancer patients choosing active surveillance follow monitoring guidelines

A new approach to predict complications after surgery for patients with larynx cancer

NCCN and AstraZeneca collaborate to improve care processes for lung cancer patients

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

Study highlights the need to educate oncologists about molecular profiling

Women in low- and middle-income countries need radiotherapy to treat their cervical cancer

Surgery can be beneficial for one type of primary central nervous system lymphoma

Researchers develop new artificial intelligence tools to find cell’s true identity

New laboratory test has potential to accurately predict spread of breast cancer

Epigenetic research provides new approaches to cancer combination therapies

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Study: One-third of pancreatic cancer patients miss out on treatment that may extend survival

Cancer stem cells adapt to environmental conditions and undergo reversible transformations

Your guide to microplate readers for cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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