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USAMRDC receives FDA marketing approval for severe malaria treatment

The U.S. Army Medical Research and Development Command announced today that the U.S. Food and Drug Administration granted marketing approval for Artesunate for Injection, an initial treatment for severe malaria.

27 May 2020

Molecular pair offers hope for development of new Parkinson's treatment

A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson's disease, a study by Nanyang Technological University, Singapore and Harvard University has found.

27 May 2020

Mouse model mimics clinical course and pathology observed in COVID-19 patients

A mouse model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reproduces features observed in human patients, researchers report May 26 in the journal Cell Host & Microbe.

27 May 2020

Researchers develop promising immunotherapy treatment for glioblastoma

Researchers of McMaster University and the University of Toronto have developed a promising immunotherapy treatment for a deadly form of adult brain cancer called glioblastoma.

27 May 2020

Scientists use microneedle patches to extract the skin’s interstitial fluid

The interstitial fluid is a major component of the liquid environment in the body and fills the spaces between the body's cells.

27 May 2020

Updates on stem cell therapeutics and regenerative medicine

Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come.

27 May 2020

Research could help identify disturbances in the body's copper metabolism

In biology it is well-known that every living organism is triggered by the hereditary material or DNA that encodes various protein molecules, which in turn perform all the necessary biological functions and it might seem that nothing else is needed to sustain the life of an organism.

26 May 2020

'Good' bacteria have a niche in our noses, study suggests

Beneficial strains of bacteria residing in our guts, genital tracts, and skin have been shown to play a role in human health, and now, researchers publishing May 26 in the journal Cell Reports suggest that some of these "good" bacteria also have a niche in our noses.

26 May 2020

New technique for fast, easy optimization of antibodies using chicken cells

Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers refer to their technique as the human ADLib system, short for autonomously diversifying libraries.

26 May 2020

Researchers find a 'skinny' gene

Some people may have trouble losing weight, while others find it hard to gain weight. Now, a team of scientists may have found the answer to why some people remain thin despite eating without restriction.

26 May 2020

New design strategy marks a potential advance in the fight against Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

New study pinpoints ideal antiviral targets within the SARS-CoV-2 viral cycle

A specific biophysical model for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows how potential drugs inhibiting both viral transcription and translation would be particularly effective against coronavirus disease (COVID-19). The model was developed by University of Minnesota researchers and described in their recent publication available on the bioRxiv preprint server.

25 May 2020

Platinum-based chemotherapy may improve outcomes for some metastatic pancreatic cancer patients

Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations.

22 May 2020

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

Two novel biomarkers have been found to correlate with improved outcomes with immunotherapy in metastatic breast cancer and may help to identify the patients most likely to benefit from this treatment, according to exploratory studies reported at the ESMO Breast Cancer Virtual Meeting 2020.

22 May 2020

Genetic discoveries show promise for developing new treatment targets for schizophrenia

In recent years, genome-wide association studies (GWAS) have identified many different genetic variants associated with schizophrenia.

22 May 2020

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory and inflammatory diseases, and Celonic Group, a premium biopharmaceutical CDMO specialized in the development and production of Advance Therapy Medicinal Products (ATMPs) and mammalian cell line-expressed biotherapeutics, today announced a collaboration to produce the novel human recombinant protein AT-100 (rhSP-D) as a therapeutic candidate against COVID-19.

21 May 2020

UBC scientists discover gene that plays a role in resisting weight gain

Why can some people eat as much as they want, and still stay thin?

21 May 2020

Bioinsider launches COVID-19 virtual meeting series

Bioinsider has opened registration and a call for speaker proposals for its four-part virtual meeting series, Together as One COVID-19 Series.

21 May 2020

MIT researchers describe new methods for accelerating drug approvals during pandemics

In response to the COVID-19 pandemic, researchers from the Massachusetts Institute of Technology have published a pair of studies in a COVID-19 special issue of the Harvard Data Science Review, freely available via open access, describing new methods for accelerating drug approvals during pandemics and for providing more accurate measures of the probabilities of success for clinical trials of vaccines and other anti-infective therapies.

20 May 2020

Doctoral candidate receives NIH fellowship to study how adenovirus affects heart function

A dose of adenovirus hits most people like a common cold - a cough, a fever, maybe a sore throat. But for an unfortunate few, the usually benign bug hacks the heart's cellular electrical communication system and sometimes proves fatal.

20 May 2020