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Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

Researchers emphasize that an effective vaccine should induce mucosal immunity and prevent the nasal entry of SARS-CoV-2.

27 Oct 2021

A study on the SARS-CoV-2 B.1.620 lineage

In a recently published Nature Communications study, the authors describe the B.1.620 lineage discovered in Lithuania.

27 Oct 2021

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that is not intentionally targeted by any available therapeutics but is widely expressed in human melanoma.

27 Oct 2021

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

The heterologous ChAd/BNT combination confers better protection against SARS-CoV-2 infection than the homologous BNT/BNT combination in a real-world observational study of healthcare workers.

27 Oct 2021

Study of SARS-CoV-2 antibody seroprevalence among domestic cats

Researchers from the University of Veterinary Medicine Hannover have been investigating the spread of the disease in domestic cats in Europe.

27 Oct 2021

Model for the simulation of SARS-CoV-2 community transmission in congregate facilities

Researchers have examined the factors that caused the most significant outbreaks in congregate settings such as care homes and prisons.

27 Oct 2021

New study explains why Delta is so easily transmitted and infects people quickly

The Delta variant of SARS-CoV-2 has swept the globe, becoming the dominant variant within just a few months. A new study from Boston Children's Hospital, published today in Science, explains why Delta is so easily spread and infects people so quickly, and suggests a more targeted strategy for developing future COVID-19 vaccines and treatments.

27 Oct 2021

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Researchers in the United States have conducted a study showing that Moderna’s coronavirus disease 2019 (COVID-19) vaccine provided durable protection against the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques.

26 Oct 2021

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

In the worldwide effort to battle SARS-CoV-2, the virus that causes COVID-19, researchers have often turned to medications used as therapies for other conditions in the hopes of finding ones that either kill the coronavirus or lessen the impacts from its infection.

26 Oct 2021

A high-throughput pipeline for identifying nanobodies that target and neutralize SARS-CoV-2

Researchers in the United States have developed a cost-effective, high-throughput pipeline for identifying effective nanobodies that target and neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

26 Oct 2021

Hyperimmune antibody produced in horses may be an efficient approach to combat covid-19

A study conducted by a consortium of Brazilian researchers has demonstrated that a hyperimmune serum consisting of purified antibody fragments produced in horses may be an efficient approach to combat covid-19.

26 Oct 2021

Lung cancer-associated fibroblasts could guide the design of personalized treatments

Three subtypes of cancer-associated fibroblasts (CAF) could guide the design of personalized treatment for lung cancer patients, according to a new study in Cancer Cell led by researchers at Massachusetts General Hospital.

26 Oct 2021

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Israeli researchers evaluate the antibody response in ICPs to assess antibody-mediated immunity following vaccination with the Pfizer-BioNTech vaccine.

26 Oct 2021

Study finds SARS-CoV-2 infection is proportional to cell surface ACE2 levels

Researchers from Oregon State University have developed a system to assess the ability of SARS-CoV-2 to bind to ACE2 orthologs.

26 Oct 2021

Study identifies how cancer cells transform macrophages into supporters of their growth

A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival.

26 Oct 2021

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

In a paper recently published in the journal Science Translational Medicine by Bordt et al. (October 19th, 2021), maternal SARS-CoV-2 infections are studied with particular regard to maternal-fetal antibody transfer and virus-induced placental interferon responses, finding a sexually dimorphic response that results in lesser antibody transfer to the male fetus.

26 Oct 2021

Immune response to mRNA COVID vaccines delayed in pregnant women

Researchers in the United States have conducted comprehensive profiling of humoral immune responses in pregnant, lactating, and non-pregnant women following coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination to probe differences in vaccine-induced immunity.

25 Oct 2021

N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections

A study in the Philadelphia area found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants evolve to become more contagious and resistant to COVID-19 vaccines. In addition, depending on the sublineage, SARS-CoV-2 variants such as the Delta variant led to a three-fold increased risk for vaccine breakthrough cases.

25 Oct 2021

A new vaccine approach that could prevent future pandemics

News-Medical speaks to Professor Tomohiro Kurosaki about how he has developed a new vaccine approach that could prevent future pandemics.

25 Oct 2021

Are non-human primates at risk of SARS-CoV-2 exposure through wastewater contact?

Researchers have been investigating the potential for SARS-CoV-2 to spread to NHP through wastewater.

25 Oct 2021

Receptor News and Research

Study shows efficacy of a heterologous vaccine regimen to induce mucosal protection against COVID-19

A study on the SARS-CoV-2 B.1.620 lineage

Prostate cancer drugs could be effectively repurposed to inhibit melanoma in men

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination amongst healthcare workers

Study of SARS-CoV-2 antibody seroprevalence among domestic cats

Model for the simulation of SARS-CoV-2 community transmission in congregate facilities

New study explains why Delta is so easily transmitted and infects people quickly

Moderna’s COVID-19 vaccine provides durable protection against SARS-CoV-2 delta in macaques

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

A high-throughput pipeline for identifying nanobodies that target and neutralize SARS-CoV-2

Hyperimmune antibody produced in horses may be an efficient approach to combat covid-19

Lung cancer-associated fibroblasts could guide the design of personalized treatments

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Study finds SARS-CoV-2 infection is proportional to cell surface ACE2 levels

Study identifies how cancer cells transform macrophages into supporters of their growth

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

Immune response to mRNA COVID vaccines delayed in pregnant women

N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections

A new vaccine approach that could prevent future pandemics

Are non-human primates at risk of SARS-CoV-2 exposure through wastewater contact?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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