Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate stubborn reservoirs of breast and ovarian cancer stem cells (CSCs).

4 Oct 2016

UEF research shows retinal changes may be detected earlier than brain changes

Diseases of the central nervous system (CNS) may manifest as pathological changes in the retina of the eye.

3 Oct 2016

Scientists establish new framework for studying psychiatric pathology

The case-control method, where researchers compare patients with a particular disease to healthy control participants, has increased understanding of disease-related effects at a group level.

30 Sep 2016

Mayo Clinic's biorepository earns CAP accreditation for high-quality operations

The Mayo Clinic Center for Individualized Medicine's biorepository has earned the College of American Pathologists biorepository accreditation, an internationally recognized gold standard of operational excellence.

30 Sep 2016

University of Pennsylvania receives NSF grant to establish Center for Engineering Mechanobiology

The National Science Foundation has awarded the University of Pennsylvania a $24 Million, five-year grant to establish a Science and Technology Center focused on engineering mechanobiology, or the way cells exert and are influenced by the physical forces in their environment.

30 Sep 2016

Abnormal protein in the brain may play important role in development of Alzheimer's disease

A recently-recognized pathologic protein in the brain may play a larger role in the development of clinical Alzheimer's disease dementia than previously recognized, according to a study by researchers at Rush University Medical Center.

30 Sep 2016

HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows

Every 20 minutes, someone in the United States receives a cancer diagnosis related to human papillomavirus. HPV causes cancer of the cervix, anus and throat.

29 Sep 2016

Tumor Paint lights the way for surgeons during brain surgery

In December of last year, Laura Coffman began to notice that something wasn't quite right with her 2-year-old son, Hunter. He was leaning to one side and seemed to lose his balance easily. When he became lethargic and started vomiting a few days later on Dec. 28, she knew it was time to see the pediatrician.

28 Sep 2016

Experimental PET tracer can diagnose concussion-related brain degeneration in living person

An experimental positron emission tomography (PET) tracer can effectively diagnose concussion-related brain degeneration while a person is still alive, according to a proof-of-concept study conducted at the Icahn School of Medicine at Mount Sinai and published September 27 in the journal Translational Psychiatry.

27 Sep 2016

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

A supplemental "boost" of radiation improves local control and provides an incremental benefit in decreasing breast cancer recurrence for patients with Ductal Carcinoma In Situ (DCIS) who receive whole breast radiation therapy radiation (WBRT) following lumpectomy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

27 Sep 2016

Association for Molecular Pathology announces winners of 2016 awards

The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostics professionals, today announced the recipients of the Jeffrey A. Kant Leadership Award and the AMP Meritorious Service Award. Together with the AMP Award for Excellence in Molecular Diagnostics, these awards will be presented at the AMP 2016 Annual Meeting.

27 Sep 2016

Cross-disciplinary concepts may lead to effective, personalised cancer treatments

It is not only tumours and metastases that differ in each type of cancer and each individual sufferer but also receptors in cells.

27 Sep 2016

Specific high-fat diets linked to increased tumor formation in mouse model of intestinal cancer

A high-fat-diet-induced immune reaction causes inflammation leading to intestinal cancer in a mouse model - even among animals that are not obese -- according to a new study from the Perelman School of Medicine at the University of Pennsylvania, Case Western Reserve University, the Pacific Northwest Research Institute, and others.

26 Sep 2016

High levels of dietary zinc increase susceptibility to Clostridium difficile infections

Too much dietary zinc increases susceptibility to infection by Clostridium difficile - "C. diff" - the most common cause of hospital-acquired infections.

26 Sep 2016

Veracyte announces new data suggesting ability of Afirma GEC in thyroid cancer diagnosis

Veracyte, Inc.today announced new data suggesting the potential to enhance the performance of the Afirma Gene Expression Classifier in thyroid cancer diagnosis by combining the test's proven RNA expression-based capabilities with gene variant and fusion information – all on a single, robust RNA sequencing platform.

24 Sep 2016

Yale researchers compare efficacy of four PD-L1 assay tests

In a recent study, a Yale Cancer Center team compared the performance of the four available PD-L1 assay tests.

23 Sep 2016

microDimensions to host two compact digital pathology webinars on 11 October, 2016

microDimensions is hosting two compact digital pathology webinars back to back on Oct 11th.

From microDimensions - Bramlage Scientific GmbH 23 Sep 2016

New study to examine effectiveness of orally administered drug in treating stuttering

Stuttering, an interruption in the flow of speech, affects about three million Americans. It begins most often in childhood, affecting four men for every woman. A precise cause of this complex communicative disorder is not known.

23 Sep 2016

Comprehensive review confirms no-calorie sweetener not linked to cancer

In a society where obesity is increasingly recognized as a risk factor for disease, low- and no-calorie ingredients are logical choices for those wishing to manage their weight.

22 Sep 2016

JAK inhibitors may be first effective treatment for people with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata—an autoimmune disease that causes patchy, and less frequently, total hair loss—had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

22 Sep 2016

Pathology News and Research

Further Reading

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

UEF research shows retinal changes may be detected earlier than brain changes

Scientists establish new framework for studying psychiatric pathology

Mayo Clinic's biorepository earns CAP accreditation for high-quality operations

University of Pennsylvania receives NSF grant to establish Center for Engineering Mechanobiology

Abnormal protein in the brain may play important role in development of Alzheimer's disease

HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows

Tumor Paint lights the way for surgeons during brain surgery

Experimental PET tracer can diagnose concussion-related brain degeneration in living person

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

Association for Molecular Pathology announces winners of 2016 awards

Cross-disciplinary concepts may lead to effective, personalised cancer treatments

Specific high-fat diets linked to increased tumor formation in mouse model of intestinal cancer

High levels of dietary zinc increase susceptibility to Clostridium difficile infections

Veracyte announces new data suggesting ability of Afirma GEC in thyroid cancer diagnosis

Yale researchers compare efficacy of four PD-L1 assay tests

microDimensions to host two compact digital pathology webinars on 11 October, 2016

New study to examine effectiveness of orally administered drug in treating stuttering

Comprehensive review confirms no-calorie sweetener not linked to cancer

JAK inhibitors may be first effective treatment for people with alopecia areata

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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