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New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Study reveals survival benefit from genome-matched cancer treatments in rural Maine

In 2016, The Jackson Laboratory (JAX), a National Cancer Institute-designated Cancer Center and at the forefront of cancer research, launched the Maine Cancer Genomics Initiative (MCGI) to bring the latest progress in cancer care to rural Maine patients.

1 May 2024

Electric pulses boost gene therapy uptake in liver cells

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies.

30 Apr 2024

Study highlights differences in pancreatic cancer cells based on location

A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors that could lead to better targeted treatments.

30 Apr 2024

Disruption of smoking cessation medicine linked to avoidable deaths

The disruption to the supply of a prescription medicine that helps people stop smoking may have led to thousands fewer people quitting each year in England, which will lead to avoidable deaths in future, suggests a new study led by UCL (University College London) researchers.

30 Apr 2024

Perimenopausal women face elevated depression risk, study finds

Women are 40% more likely to experience depression in the perimenopause than those who aren't experiencing any menopausal symptoms, finds a new study led by UCL researchers.

30 Apr 2024

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

Illumina, a global genomics and human health company, has partnered with the Garvan Institute of Medical Research's TenK10K project to help transform the treatment of complex diseases, starting with autoimmune diseases, with a joint investment of $27 million AUD.

30 Apr 2024

New monoclonal antibody vaccine slashes malaria risk in children

A recent study demonstrates that the monoclonal antibody-based vaccine L9LS is safe for children aged 6 to 10 and significantly reduces the risk of malaria infection and clinical symptoms by 70% and 77%, respectively.

30 Apr 2024

Listening to mindfulness audio recordings eases side effects of radiation therapy

Men with prostate cancer who are treated with radiation therapy experience significant side effects such as fatigue, sleep problems, anxiety and depressive symptoms. But listening to mindfulness audio recordings significantly eased those symptoms, a new Northwestern Medicine study has found.

30 Apr 2024

New biomarker predicts immunotherapy response in gastrointestinal cancers

Despite significant progress in treating gastrointestinal (GI) cancers through surgical resection, chemotherapy, radiotherapy, and targeted therapy, the objective response rate (ORR) for immune checkpoint inhibitor (ICI) therapy remains low.

30 Apr 2024

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts.

30 Apr 2024

An Arm and a Leg: The hack

When Change Healthcare, a subsidiary of UnitedHealth Group, got hit by a cyberattack this winter, a big chunk of the nation's doctors, pharmacists, hospitals, and therapists stopped getting paid.

30 Apr 2024

Fentanyl inhalation linked to irreversible brain damage

Inhaling the synthetic opioid fentanyl may cause potentially irreversible brain damage (toxic leukoencephalopathy), warn doctors in the journal BMJ Case Reports, after treating a middle aged man found unresponsive in his hotel room after snorting the drug.

29 Apr 2024

Atrial fibrillation linked to high mortality and hospitalization rates, UQ study shows

Forty-five per cent of patients admitted to hospital for atrial fibrillation (AF) in Australia and New Zealand die within a decade, according to University of Queensland research.

29 Apr 2024

STRONG STAR Consortium awarded $17M for traumatic brain injury and psychological health research

In a recent round of grant awards, the STRONG STAR Consortium based at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) was selected by the U.S. Department of Defense for a total of $17 million in funding to launch eight new research projects focused on traumatic brain injury and psychological health.

29 Apr 2024

Therapy News and Research

New drug candidate reverses obesity in mice by transforming liver metabolism

Study reveals survival benefit from genome-matched cancer treatments in rural Maine

Electric pulses boost gene therapy uptake in liver cells

Study highlights differences in pancreatic cancer cells based on location

Disruption of smoking cessation medicine linked to avoidable deaths

Perimenopausal women face elevated depression risk, study finds

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

New monoclonal antibody vaccine slashes malaria risk in children

Listening to mindfulness audio recordings eases side effects of radiation therapy

New biomarker predicts immunotherapy response in gastrointestinal cancers

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

An Arm and a Leg: The hack

Fentanyl inhalation linked to irreversible brain damage

Atrial fibrillation linked to high mortality and hospitalization rates, UQ study shows

STRONG STAR Consortium awarded $17M for traumatic brain injury and psychological health research

Experimental monoclonal antibody prevents and reverses clinical type 1 diabetes in mice

Benefits and challenges of integrating nursing home residents into clinical trials

SCA4 genetic breakthrough: Unveiling the cause of a devastating neurological disease

What Florida’s new 6-week abortion ban means for the South, and traveling patients

Aspirin's immune-boosting effects in colorectal cancer revealed

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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