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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Researchers at Icahn School of Medicine at Mount Sinai in New York have provided evidence suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was infecting people in New York City (NYC) at least one month before the first case was officially documented in the city.

14 Feb 2021

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

SARS-CoV-2 genome is three times larger than influenza genome. Both consist of NRA molecules that mutate when replicate.

13 Feb 2021

Scientists characterize genomic profile of 84 pediatric therapy-related myeloid neoplasms

Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis.

13 Feb 2021

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Researchers at the Southern Illinois University, U.S.A. have presented a comprehensive and well-validated set of working protocols for sequencing high-quality SARS-CoV-2 genomes in high throughput from patient samples.

12 Feb 2021

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.

12 Feb 2021

Portable suitcase lab for rapid detection of SARS-CoV-2

The PCR test is the most accurate tool to identify SARS-CoV-2. However, valid results are often available only after days.

12 Feb 2021

New SARS-CoV-2 variant found in newborn child with seizures in the United States

Researchers at a hospital in Washington D.C. found a new mutant strain of the virus in a neonatal patient with high viral loads. According to the authors, this strain could be spreading in the United States mid-Atlantic population and needs monitoring.

11 Feb 2021

Genomic test may help guide treatment decisions for patients with recurrent prostate cancer

A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers.

11 Feb 2021

Brain pericytes serve as a potential hub for SARS-CoV-2 infection

A team of scientists from the United States has recently conducted a study using pericyte-like cell-containing brain cortical organoids as an experimental model to investigate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the central nervous system.

11 Feb 2021

New study shares preliminary data on Pfizer vaccine’s effectiveness in Israel

Researchers have shown that by mid-January, the number of COVID-19 cases and hospitalizations in Israel began to decline with a larger and earlier decrease among older people.

11 Feb 2021

Researchers find a way to measure key characteristics of proteins that bind to RNA

A team of Case Western Reserve University researchers has found a way to measure key characteristics of proteins that bind to RNA in cells--a discovery that could improve our understanding of how gene function is disturbed in cancer, neurodegenerative disorders or infections.

11 Feb 2021

Cell-selective nanotherapy can help treat atherosclerotic plaques

Percutaneous coronary intervention (PCI), commonly known as angioplasty with a stent, opens clogged arteries and saves lives. Despite its benefit in treating atherosclerosis that causes coronary artery disease, this common minimally-invasive procedure still poses severe complications for some patients.

11 Feb 2021

Researchers identify top-performing COVID-19 POC tests

After screening more than 1,100 independently assessed, point-of-care COVID-19 tests, researchers at NSF International and Novateur Ventures have identified 5 direct (antigen/RNA) tests for detection of acute infection and 6 indirect (antibody) tests for detection of prior infection that meet the recently published World Health Organization (WHO) "desirable" Target Product Profile (TPP) criteria.

10 Feb 2021

Could a SARS-CoV-2 accessory protein be responsible for certain COVID-19 symptoms?

Researchers highlight the potential causes of some COVID-19 symptoms. Early in the pandemic, the hallmark symptoms of COVID-19 include cough, fever, and shortness of breath. As the pandemic has evolved, more symptoms have emerged, such as loss of smell and taste, headache, intestinal issues, and abdominal pains.

10 Feb 2021

Researchers develop self-assembling nanoparticle SARS-CoV-2 vaccines

Researchers in China have developed three SARS-CoV-2 nanoparticle vaccines, containing receptor-binding domain (RBD) trimer, S1 trimer, and ectodomain (ECD) trimer, respectively. To do this, they have used Ferritin nanoparticle self-assembly technology.

9 Feb 2021

COVID-19 vaccination associated with 3- to 5-fold reduction in viral load

Researchers in Israel report a reduction in viral load in vaccinated individuals.

9 Feb 2021

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

A new study provides direct evidence that the oligosaccharides attached to the viral surface spike protein are essential for viral infection, offering new approaches to preventive and therapeutic drugs.

9 Feb 2021

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

Researchers report the association of subgenomic RNA (sgRNA) production, the structural differences between sgRNA variants, and clinical severity in 81 clinical specimens obtained from both asymptomatic and symptomatic individuals with SARS-CoV-2 infection.

9 Feb 2021

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

Study explores how membraneless organelles form and organize themselves

In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA.

9 Feb 2021

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Further Reading

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

New tool enables study of SARS-CoV-2 mutant spectrum by ultrasequencing

Scientists characterize genomic profile of 84 pediatric therapy-related myeloid neoplasms

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

Portable suitcase lab for rapid detection of SARS-CoV-2

New SARS-CoV-2 variant found in newborn child with seizures in the United States

Genomic test may help guide treatment decisions for patients with recurrent prostate cancer

Brain pericytes serve as a potential hub for SARS-CoV-2 infection

New study shares preliminary data on Pfizer vaccine’s effectiveness in Israel

Researchers find a way to measure key characteristics of proteins that bind to RNA

Cell-selective nanotherapy can help treat atherosclerotic plaques

Researchers identify top-performing COVID-19 POC tests

Could a SARS-CoV-2 accessory protein be responsible for certain COVID-19 symptoms?

Researchers develop self-assembling nanoparticle SARS-CoV-2 vaccines

COVID-19 vaccination associated with 3- to 5-fold reduction in viral load

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

A precursor to remdesivir shows therapeutic potential for COVID-19

Study explores how membraneless organelles form and organize themselves

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